Reactome: A Curated Pathway Database

APP gene expression

Stable Identifier
R-HSA-8870710
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Transcription of the APP gene is increased by FOXO3, downstream of FOXO3 phosphorylation by aberrantly activated CDK5 (Shi et al. 2016).

Literature References
Participants
Participant Of
This entity is regulated by:
Disease
Diseases
Name Identifier Synonyms
Alzheimer's disease 10652 AD, Alzheimers dementia, Alzheimer disease