YAP1 binds TEAD2

Stable Identifier
R-HSA-8871260
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
YAP1 binds TEAD2
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The YAP1 transcriptional coactivator can bind any one of the four TEAD transcription factors to form a complex. The stoichiometry of this complex is unknown (Chan et al. 2009).
Literature References
PubMed ID Title Journal Year
19324876 TEADs mediate nuclear retention of TAZ to promote oncogenic transformation

Lim, CJ, Hong, W, Loo, LS, Huang, C, Chan, SW, Chong, YF

J Biol Chem 2009
Participants
Input
Output
Participates
as an event of
Orthologous Events
YAP1 binds TEAD2 (Bos taurus)
YAP1 binds TEAD2 (Caenorhabditis elegans)
YAP1 binds TEAD2 (Canis familiaris)
YAP1 binds TEAD2 (Mus musculus)
YAP1 binds TEAD2 (Rattus norvegicus)
YAP1 binds TEAD2 (Sus scrofa)
YAP1 binds TEAD2 (Xenopus tropicalis)
Authored
D'Eustachio, P  (2012-02-03)
Reviewed
Sudol, M  (2012-02-03)
Created
Jupe, S  (2016-05-13)
Cite Us!