Reactome | CREB3L3 [Golgi membrane]

CREB3L3 [Golgi membrane]

Stable Identifier

R-HSA-8874144

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Cyclic AMP-responsive element-binding protein 3-like protein 3, CR3L3_HUMAN, CREB-H

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q68CJ9 CREB3L3

Gene Names

CREB3L3, CREBH, HYST1481

Chain

chain:1-461, chain:1-

Reference Genes

BioGPS Gene:84699 CREB3L3

COSMIC (genes):CREB3L3 CREB3L3

CTD Gene:84699 CREB3L3

dbSNP Gene:84699 CREB3L3

ENSEMBL:ENSG00000060566 CREB3L3

HGNC:18855 CREB3L3

KEGG Gene (Homo sapiens):84699 CREB3L3

Monarch:84699 CREB3L3

NCBI Gene:84699 CREB3L3

OMIM:611998 CREB3L3

UCSC:Q68CJ9 CREB3L3

Reference Transcript

Other Identifiers

0007000072

11735734_a_at

11735735_x_at

11735736_a_at

16857093

234361_at

3817318

3817319

3817320

3817321

3817322

3817323

3817324

3817325

3817326

3817327

3817329

3817330

3817331

3817332

3817333

8024754

84699

A_23_P108082

A_24_P57207

GE83454

GO:0000139

GO:0000228

GO:0000790

GO:0000976

GO:0000977

GO:0000981

GO:0001228

GO:0002675

GO:0003674

GO:0003677

GO:0003700

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005783

GO:0005789

GO:0005794

GO:0005829

GO:0006355

GO:0006950

GO:0006986

GO:0007165

GO:0008150

GO:0009058

GO:0016020

GO:0016021

GO:0030968

GO:0034641

GO:0035497

GO:0042803

GO:0043226

GO:0045944

GO:0046982

GO:1990440

Hs.247744.0.S1_3p_at

ILMN_1779524

PH_hs_0013107

TC19000081.hg

Participant Of

input

MBTPS1 (S1P) cleaves CREB3L3

output

CREB3L3 translocates from the endoplasmic reticulum membrane to the Golgi membrane

Other forms of this molecule

CREB3L3(1-?) [nucleoplasm]

CREB3L3(1-?) [cytosol]

CREB3L3 [endoplasmic reticulum membrane]

CREB3L3(?-461) [endoplasmic reticulum membrane]

CREB3L3(365-461) [Golgi membrane]

CREB3L3(1-364) [Golgi membrane]

CREB3L3(1-323) [cytosol]

CREB3L3(1-323) [nucleoplasm]

CREB3L3(324-364) [Golgi membrane]

Inferred To

Creb3l3 [Golgi membrane] (Mus musculus)

Creb3l3 [Golgi membrane] (Rattus norvegicus)

creb3l3b [Golgi membrane] (Danio rerio)

let-607 [Golgi membrane] (Caenorhabditis elegans)

CREB3L3 [Golgi membrane] (Canis familiaris)

CREB3L3 [Golgi membrane] (Gallus gallus)

CREB3L3 [Golgi membrane] (Sus scrofa)

Cross References

RefSeq

NP_115996.1, NP_001258926.1, NP_001258925.1, NP_001258924.1

OpenTargets

ENSG00000060566

HPA

ENSG00000060566-CREB3L3

GeneCards

Q68CJ9

Ensembl

ENST00000595923, ENSP00000469355, ENSP00000472399, ENSG00000060566, ENSP00000078445, ENST00000602257, ENSP00000470119, ENST00000602147, ENST00000078445

PRO

Q68CJ9

Orphanet

21607

HMDB Protein

HMDBP08121

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NUM3 S39A9			0.556	3
UniProt:Q96EC8 YIPF6	2	YIPF6 [cytoplasmic vesicle membrane] (R-HSA-434199) YIPF6 [Golgi membrane] (R-HSA-434346)	0.556	3
UniProt:O00155 GPR25	1	GPR25 [plasma membrane] (R-HSA-6805220)	0.556	3
UniProt:Q96LK0 CEP19			0.556	3
UniProt:Q96GQ5 RUSF1			0.556	3
UniProt:Q8NBI2 CYAC3			0.556	3
UniProt:Q9C005 DPY30	1	DPY30 [nucleoplasm] (R-HSA-5669104)	0.556	3
UniProt:Q5J8X5 M4A13			0.556	3
UniProt:O43765 SGTA	1	SGTA [cytosol] (R-HSA-5423595)	0.556	3
UniProt:Q8WW34-2 TMEM239			0.556	3
UniProt:Q96EQ0 SGTB			0.556	3
UniProt:Q969F0 FATE1			0.556	3
UniProt:Q96EZ8 MCRS1	1	MCRS1 [nucleoplasm] (R-HSA-3321849)	0.556	3
UniProt:Q9Y228 T3JAM			0.556	3
UniProt:Q02094 RHAG	7	RHAG G280R [plasma membrane] (R-HSA-5623021) RHAG G380V [plasma membrane] (R-HSA-5623035) RHAG S79N [plasma membrane] (R-HSA-5623026) RHAG V270I [plasma membrane] (R-HSA-5623024) RHAG A363Lfs15 [plasma membrane] (R-HSA-5623025) RHAG P52Dfs57 [plasma membrane] (R-HSA-5623046) RHAG [plasma membrane] (R-HSA-444408)	0.556	3
UniProt:Q8N8B7-2 TCEANC			0.556	3
UniProt:Q9NVC3 S38A7			0.556	3
UniProt:Q13190 STX5	5	STX5 [endoplasmic reticulum membrane] (R-HSA-5689474) STX5 [Golgi membrane] (R-HSA-6807771) STX5 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688157) STX5 [ER to Golgi transport vesicle membrane] (R-HSA-5689838) STX5 [cytosol] (R-HSA-9613991)	0.556	3
UniProt:P18850 ATF6	7	ATF6(420-670) [Golgi membrane] (R-HSA-420814) ATF6 [endoplasmic reticulum membrane] (R-HSA-381222) ATF6 [Golgi membrane] (R-HSA-381000) ATF6(380-419) [Golgi membrane] (R-HSA-420817) ATF6(1-419) [Golgi membrane] (R-HSA-420815) ATF6(1-380) [nucleoplasm] (R-HSA-381211) ATF6(1-380) [cytosol] (R-HSA-381075)	0.524	2

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