Reactome | CREB3L1(1-426) [Golgi membrane]

CREB3L1(1-426) [Golgi membrane]

Stable Identifier

R-HSA-8874153

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Synonyms

Cyclic AMP-responsive element-binding protein 3-like protein 1, CR3L1_HUMAN, OASIS

Locations in the PathwayBrowser for interactor UniProt:Q6PI25 CNIH2

Expand all

Literature References

PubMed ID	Title	Journal	Year
16417584	Cleavage of the membrane-bound transcription factor OASIS in response to endoplasmic reticulum stress Murakami, T, Kondo, S, Ogata, M, Kanemoto, S, Saito, A, Wanaka, A, Imaizumi, K	J. Neurochem.	2006

External Reference Information

External Reference

UniProt:Q96BA8 CREB3L1

Gene Names

CREB3L1, OASIS, PSEC0238

Chain

chain:1-519, chain:1-

Reference Genes

BioGPS Gene:90993 CREB3L1

COSMIC (genes):CREB3L1 CREB3L1

CTD Gene:90993 CREB3L1

dbSNP Gene:90993 CREB3L1

ENSEMBL:ENSG00000157613 CREB3L1

HGNC:18856 CREB3L1

KEGG Gene (Homo sapiens):90993 CREB3L1

Monarch:90993 CREB3L1

NCBI Gene:90993 CREB3L1

OMIM:616215 CREB3L1

UCSC:Q96BA8 CREB3L1

Reference Transcript

RefSeq:NM_052854.3 CREB3L1

Other Identifiers

0003710397

11720678_a_at

11749509_a_at

16724269

213059_at

213498_at

24069

26151

3329207

3329208

3329220

3329223

3329225

3329226

3329227

3329228

3329229

3329230

3329233

3329234

3329236

3329238

3329239

3329240

3329241

41867_at

46115_at

7939642

90993

A_14_P124912

A_23_P150407

AAH14097

AAH15781

AB063321

AK075538

BAC01278

BAC11681

BC014097

BC015781

CAB026151

CCDS53620

CREB3L1

CREB3L1-206

E9PK33

ENSG00000157613

ENSP00000481956

ENST00000621158

ENST00000621158.4

EntrezGene:90993

EntrezGene:CREB3L1

GE54511

GO:0000122

GO:0000228

GO:0000790

GO:0000981

GO:0001227

GO:0001228

GO:0001649

GO:0003674

GO:0003677

GO:0003682

GO:0003700

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005694

GO:0005737

GO:0005783

GO:0005789

GO:0006355

GO:0006810

GO:0006950

GO:0006986

GO:0007165

GO:0007275

GO:0008150

GO:0008219

GO:0009058

GO:0010629

GO:0016020

GO:0016021

GO:0030154

GO:0030198

GO:0030968

GO:0032967

GO:0034641

GO:0035497

GO:0040037

GO:0043226

GO:0044212

GO:0045892

GO:0045944

GO:0046332

GO:0048646

GO:0048856

GO:0070278

GO:1902236

GO:1903671

GO:1990440

H0YEU7

HGNC:18856

HPA024069

Hs.13456.0.S1_3p_at

Hs.13456.1.S1_3p_at

ILMN_1749032

IPR001630

IPR004827

IPR029805

MIM:616215

MIM:616229

NM_052854

NP_443086

PF00170

PH_hs_0019227

PR00041

SM00338

TC11000394.hg

UPI000004ABFF

XM_006718380

XP_006718443

Participant Of

input

MBTPS2 (S2P) cleaves CREB3L1

output

MBTPS1 (S1P) cleaves CREB3L1

Other forms of this molecule

CREB3L1 [Golgi membrane]

CREB3L1(427-519) [Golgi membrane]

CREB3L1 [endoplasmic reticulum membrane]

CREB3L1(1-375) [cytosol]

CREB3L1(376-426) [Golgi membrane]

CREB3L1(1-375) [nucleoplasm]

Cross References

RefSeq

NP_443086.1

OpenTargets

ENSG00000157613

GeneCards

Q96BA8

PRO

Q96BA8

Orphanet

18653

HMDB Protein

HMDBP08119

Interactors (226)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P60201-2 PLP1			0.795	11
UniProt:Q8IWU4 SLC30A8	1	SLC30A8 [secretory granule membrane] (R-HSA-437106)	0.795	8
UniProt:O00155 GPR25	1	GPR25 [plasma membrane] (R-HSA-6805220)	0.764	6
UniProt:P30536 TSPO	1	TSPO [mitochondrial outer membrane] (R-HSA-2980957)	0.764	6
UniProt:Q9BVK8 TM147			0.764	6
UniProt:Q6N075 MFSD5			0.696	5
UniProt:Q969S0 SLC35B4	1	SLC35B4 [Golgi membrane] (R-HSA-742365)	0.696	5
UniProt:A2RU14 TM218			0.696	5
UniProt:Q9H0Q3 FXYD6	1	FXYD6 [plasma membrane] (R-HSA-2752104)	0.696	5
UniProt:Q9UHJ9-5 PGAP2			0.696	5
UniProt:Q9BXR6 CFHR5	1	CFHR5 [extracellular region] (R-HSA-8851419)	0.696	5
UniProt:Q92520 FAM3C	2	FAM3C [platelet dense granule lumen] (R-HSA-8848884) FAM3C [extracellular region] (R-HSA-8848922)	0.666	4
UniProt:O43741 PRKAB2	3	PRKAB2 [nucleoplasm] (R-HSA-164096) PRKAB2 [cytosol] (R-HSA-200413) PRKAB2 [cytosol] (R-HSA-200411)	0.666	4
UniProt:P17152 TMEM11	1	TMEM11 [mitochondrial inner membrane] (R-HSA-8949578)	0.621	3
UniProt:P40107 GMT1			0.61	4
UniProt:P46956 PHO86			0.61	4
UniProt:P40471 AYR1			0.556	3
UniProt:Q03697 YMD8			0.556	3
UniProt:P38842 YHU0			0.556	3
UniProt:Q8N5M9 JAGN1			0.556	3
UniProt:A0A0S2Z5R8 A0A0S2Z5R8			0.556	3
UniProt:Q8IXM6 NRM			0.556	3
UniProt:P47088 GPI14			0.556	3
UniProt:E9PRZ2 E9PRZ2			0.556	3
UniProt:P60201 MYPR			0.556	3
UniProt:P53906 YNO6			0.556	3
IntAct:EBI-11522518 OST2			0.556	3
UniProt:P40152 YNV7			0.556	3
UniProt:Q8TGQ7 YP159			0.556	3
UniProt:P50076 DIE2	1	DIE2 [endoplasmic reticulum membrane] (R-SCE-449658)	0.556	3
UniProt:Q12006	1	ZDHHC21 [Golgi membrane] (R-SCE-203757-5)	0.556	3
UniProt:Q12382 DGK1			0.556	3
UniProt:P47111 VPS55			0.556	3
UniProt:Q06144	3	ORMDL3 [plasma membrane] (R-SCE-6806293-2) ORMDL3 [secretory granule membrane] (R-SCE-6800882-2) ORMDL3 [specific granule membrane] (R-SCE-6799643-2)	0.556	3
UniProt:Q06455-4 RUNX1T1			0.556	3
UniProt:Q8WY98 TM234			0.556	3
UniProt:Q04969 SPC2			0.556	3
UniProt:P40260 MEP1			0.556	3
UniProt:P40074	5	SLC38A3 [plasma membrane] (R-SCE-352171-2) SLC38A5 [plasma membrane] (R-SCE-352167-2) SLC38A4 [plasma membrane] (R-SCE-352134-2) SLC38A2 [plasma membrane] (R-SCE-352093-2) SLC38A1 [plasma membrane] (R-SCE-212663-2)	0.556	3
UniProt:Q12207 NCE2			0.556	3
UniProt:Q02774 SHR3			0.556	3
UniProt:Q6IB11 Q6IB11			0.556	3
UniProt:P47155 ILM1			0.556	3
UniProt:P26678 PLN	2	PLN [sarcoplasmic reticulum membrane] (R-HSA-5490319) p-S16-PLN [sarcoplasmic reticulum membrane] (R-HSA-5578813)	0.556	3
UniProt:P23968	3	ATP6V0B [phagocytic vesicle membrane] (R-SCE-1222695) ATP6V0B [lysosomal membrane] (R-SCE-9640187) ATP6V0B [endosome membrane] (R-SCE-912584)	0.556	3
UniProt:P38894 FLO5			0.556	3
UniProt:P38775 YHK5			0.556	3
UniProt:P47124 HOC1			0.556	3
UniProt:P40857	2	PTPLA [endoplasmic reticulum membrane] (R-SCE-5676076) PTPLB [endoplasmic reticulum membrane] (R-SCE-5676075)	0.556	3
UniProt:P40501	5	SLC38A3 [plasma membrane] (R-SCE-352171-3) SLC38A5 [plasma membrane] (R-SCE-352167-3) SLC38A4 [plasma membrane] (R-SCE-352134-3) SLC38A2 [plasma membrane] (R-SCE-352093-3) SLC38A1 [plasma membrane] (R-SCE-212663-3)	0.556	3
UniProt:P47190 PMT3			0.556	3
UniProt:P38374	1	SERP1 [cytosol] (R-SCE-5250574)	0.556	3
UniProt:P40533 TED1			0.556	3
UniProt:P38695 HXT5			0.556	3
UniProt:Q12746 PGA3			0.556	3
UniProt:Q03362 YD476			0.556	3
UniProt:Q9UHJ9 PGAP2			0.556	3
UniProt:P25619 HSP30			0.556	3
UniProt:P42836	1	ZDHHC21 [Golgi membrane] (R-SCE-203757)	0.556	3
UniProt:Q12078 SMF3			0.556	3
UniProt:P53173	2	CNIH2 [endoplasmic reticulum membrane] (R-SCE-5689442-2) CNIH1 [endoplasmic reticulum membrane] (R-SCE-5689439-2)	0.556	3
UniProt:P53053 COS12			0.556	3
UniProt:P01031 C5	7	C5a [extracellular region] (R-HSA-173677) C5(965-1676) [extracellular region] (R-HSA-8852713) C5 beta chain [extracellular region] (R-HSA-173675) C5 alpha chain [extracellular region] (R-HSA-173673) C5b alpha' [extracellular region] (R-HSA-173672) C5a-desArg [extracellular region] (R-HSA-8852798) C5aT [extracellular region] (R-HSA-8852711)	0.556	3
UniProt:P52870 SBH1	2	SBH1 [cytosol] (R-SCE-9628663) SBH1 [endoplasmic reticulum membrane] (R-SCE-9628639)	0.556	3
UniProt:P05375	1	PEMT [endoplasmic reticulum membrane] (R-SCE-1498767)	0.556	3
UniProt:P38736	1	GOSR1 [Golgi membrane] (R-SCE-6807753)	0.556	3
UniProt:Q13021 MALL			0.488	2
UniProt:Q96MV8 ZDH15			0.488	2
UniProt:Q8WVX3-2 C4ORF3			0.488	2
UniProt:P57105 SYJ2B			0.488	2
UniProt:O00180 KCNK1	1	KCNK1 [plasma membrane] (R-HSA-1296345)	0.488	2
UniProt:O43451 MGAM	3	MGAM [plasma membrane] (R-HSA-189014) MGAM [tertiary granule membrane] (R-HSA-6801070) MGAM [ficolin-1-rich granule membrane] (R-HSA-6801081)	0.488	2
UniProt:P55061 BI1			0.488	2
UniProt:Q8NH19 OR10AG1	1	OR10AG1 [plasma membrane] (R-HSA-378675)	0.488	2
UniProt:Q9H2S6-2 TNMD			0.488	2
UniProt:Q6PI25 CNIH2	3	CNIH2 [endoplasmic reticulum membrane] (R-HSA-5689442) CNIH2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5689781) CNIH2 [ER to Golgi transport vesicle membrane] (R-HSA-5689780)	0.488	2
UniProt:O95214 LERL1			0.488	2
UniProt:Q9NTN9-2 SEMA4G			0.488	2
UniProt:Q9NRZ5 AGPAT4	1	AGPAT4 [endoplasmic reticulum membrane] (R-HSA-61809)	0.488	2
UniProt:P21145 MAL			0.488	2
UniProt:Q9NRZ7 AGPAT3	2	AGPAT3 [Golgi membrane] (R-HSA-8849239) AGPAT3 [endoplasmic reticulum membrane] (R-HSA-61807)	0.488	2
UniProt:Q96MX0 CKLF3			0.488	2
UniProt:O14569 C56D2			0.488	2
UniProt:Q96FZ5 CKLF7			0.488	2
UniProt:Q9NUM3 S39A9			0.488	2
UniProt:Q92982 NINJ1			0.488	2
UniProt:Q9P0N8 MARH2			0.488	2
UniProt:O15400 STX7			0.488	2
UniProt:O14798 TNFRSF10C	1	TNFRSF10C [plasma membrane] (R-HSA-5628831)	0.488	2
UniProt:Q8TDV0 GP151			0.488	2
UniProt:P78383 S35B1			0.488	2
UniProt:P07306 ASGR1	1	PALM-C36-ASGR1 [plasma membrane] (R-HSA-8855714)	0.488	2
UniProt:O43759-2 SYNGR1			0.488	2
IntAct:EBI-11954883 TMIE			0.488	2
UniProt:P60059 SEC61G	3	SEC61G [endoplasmic reticulum membrane] (R-HSA-265003) SEC61G [cytosol] (R-HSA-5250558) SEC61G [phagocytic vesicle membrane] (R-HSA-1236798)	0.488	2
UniProt:P02786 TFRC	5	TFRC(1-760) [endosome membrane] (R-HSA-8961829) TFRC(1-760) [plasma membrane] (R-HSA-917983) TFRC(1-760) [cytoplasmic vesicle membrane] (R-HSA-434196) TFRC(1-760) [Golgi membrane] (R-HSA-434330) TFRC(1-760) [clathrin-coated endocytic vesicle membrane] (R-HSA-8869124)	0.488	2
UniProt:Q9UNK0 STX8			0.488	2
UniProt:P21964 COMT	2	COMT [plasma membrane] (R-HSA-379386) COMT [cytosol] (R-HSA-175974)	0.488	2
UniProt:Q8NBD8 T229B			0.488	2
UniProt:Q16873 LTC4S	2	LTC4S [nuclear envelope] (R-HSA-266025) LTC4S [endoplasmic reticulum membrane] (R-HSA-2142692)	0.488	2
UniProt:Q9UGM5 FETUB			0.488	2
UniProt:Q9NZG7 NINJ2			0.488	2
UniProt:Q7RTY0 MOT13			0.488	2
UniProt:Q99519 NEU1	8	NEU1 W29* [lysosomal lumen] (R-HSA-5674174) NEU1 W23* [lysosomal lumen] (R-HSA-5674155) NEU1 E377* [lysosomal lumen] (R-HSA-5674181) NEU1 R225P [lysosomal lumen] (R-HSA-5674167) NEU1 L303P [lysosomal lumen] (R-HSA-5674182) NEU1 [extracellular region] (R-HSA-6806158) NEU1 [specific granule lumen] (R-HSA-6806148) NEU1 [lysosomal lumen] (R-HSA-1605788)	0.488	2
UniProt:P23763-3 VAMP1			0.488	2
UniProt:Q9NWW5 CLN6			0.488	2
UniProt:Q14802-3 FXYD3			0.488	2
UniProt:P11836 CD20			0.488	2
UniProt:Q4LDR2 CTXN3			0.488	2
UniProt:Q9UBY5 LPAR3	1	LPAR3 [plasma membrane] (R-HSA-419379)	0.488	2
UniProt:Q8WW34-2 TMEM239			0.488	2
UniProt:Q5GAN6 RNS10			0.488	2
UniProt:Q5TGU0 TSPO2			0.488	2
UniProt:Q9NWF4 SLC52A1	1	SLC52A1 [plasma membrane] (R-HSA-5216118)	0.488	2
UniProt:Q969S6 TM203			0.488	2
UniProt:Q08AM2 Q08AM2			0.488	2
UniProt:Q6PL45-2 BRICD5			0.488	2
UniProt:Q8TAF8 LHPL5			0.488	2
UniProt:O00767 SCD	1	SCD [endoplasmic reticulum membrane] (R-HSA-400117)	0.488	2
UniProt:Q9NP94 SLC39A2	1	SLC39A2 [plasma membrane] (R-HSA-442395)	0.488	2
UniProt:Q9UHE5 NAT8	1	NAT8 [endoplasmic reticulum membrane] (R-HSA-5692986)	0.488	2
UniProt:P01350 GAST	1	GAST(76-92) [extracellular region] (R-HSA-870266)	0.488	2
UniProt:O14925 TIMM23	2	TIMM23 [mitochondrial inner membrane] (R-HSA-1252126) TIMM23 [mitochondrial intermembrane space] (R-HSA-1299436)	0.488	2
UniProt:Q16853 AOC3	1	AOC3 [plasma membrane] (R-HSA-5696151)	0.488	2
UniProt:A0PK00 T120B			0.488	2
UniProt:Q99735 MGST2	1	MGST2 [endoplasmic reticulum membrane] (R-HSA-176058)	0.488	2
UniProt:Q53FV1 ORMDL2	1	ORMDL2 [endoplasmic reticulum membrane] (R-HSA-8865591)	0.488	2
UniProt:Q01453 PMP22			0.488	2
UniProt:Q9NQQ7-3 Q9NQQ73			0.488	2
UniProt:Q4VAQ0 Q4VAQ0			0.488	2
UniProt:Q9P0S9 TM14C			0.488	2
UniProt:Q96GM1 PLPPR2	1	LPPR2 [plasma membrane] (R-HSA-6797629)	0.488	2
UniProt:Q8N609 TR1L1			0.488	2
UniProt:Q9P0S3 ORMDL1	1	ORMDL1 [endoplasmic reticulum membrane] (R-HSA-8865584)	0.488	2
UniProt:Q8N966 ZDH22			0.488	2
UniProt:Q8TB61 SLC35B2	1	SLC35B2 [Golgi membrane] (R-HSA-741454)	0.488	2
UniProt:Q9NZ01 TECR	1	TECR [endoplasmic reticulum membrane] (R-HSA-548663)	0.488	2
UniProt:Q9Y6I9 TEX264	2	TEX264 [platelet alpha granule lumen] (R-HSA-8863000) TEX264 [extracellular region] (R-HSA-8863002)	0.488	2
UniProt:O60636 TSN2			0.488	2
UniProt:Q08629 TICN1			0.488	2
UniProt:Q04941 PLP2			0.488	2
UniProt:Q9NRQ5 SMCO4			0.488	2
UniProt:Q9H115 NAPB	1	NAPB [cytosol] (R-HSA-5688553)	0.488	2
UniProt:B2RUZ4 SMIM1			0.488	2
UniProt:Q5J8X5 M4A13			0.488	2
UniProt:Q9H2C2 ARV1	1	ARV1 [endoplasmic reticulum membrane] (R-HSA-5216144)	0.488	2
UniProt:P78329 CYP4F2	1	CYP4F2 [endoplasmic reticulum membrane] (R-HSA-211016)	0.488	2
UniProt:Q96IW7 SEC22A	3	SEC22A [endoplasmic reticulum membrane] (R-HSA-5216111) SEC22A [ER to Golgi transport vesicle membrane] (R-HSA-5688560) SEC22A [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688562)	0.488	2
UniProt:Q14508 WFDC2			0.488	2
UniProt:Q9BQB6 VKORC1	1	VKORC1 [endoplasmic reticulum membrane] (R-HSA-159746)	0.488	2
UniProt:Q96F05 CK024			0.488	2
UniProt:Q96F15 GIMA5			0.488	2
UniProt:Q01638-2 IL1RL1	1	IL1RL1-2 [extracellular region] (R-HSA-8981971)	0.488	2
UniProt:Q8TEB9 RHBL4			0.488	2
IntAct:EBI-12896319 VEZT			0.488	2
UniProt:Q9H5X1 CIA2A			0.488	2
UniProt:Q59EV6 Q59EV6			0.488	2
UniProt:Q8NHW4 CCL4L1	1	CCL4L1 [extracellular region] (R-HSA-8865389)	0.488	2
UniProt:Q9Y6G1 TM14A			0.488	2
UniProt:O95968 SG1D1			0.488	2
IntAct:EBI-13365626 FUNDC2P2			0.488	2
UniProt:Q9Y5U4 INSIG2	1	INSIG2 [endoplasmic reticulum membrane] (R-HSA-1655736)	0.488	2
UniProt:I3L0A0 I3L0A0			0.488	2
UniProt:Q5VZY2 PLPP4	1	PPAPDC1A [plasma membrane] (R-HSA-2029082)	0.488	2
UniProt:Q96PS8 AQP10	1	AQP10 [plasma membrane] (R-HSA-431709)	0.488	2
UniProt:O95393 BMP10	2	BMP10 [extracellular region] (R-HSA-8858374) BMP10(22-424) [extracellular region] (R-HSA-2396409)	0.488	2
UniProt:Q9BTX3 TM208			0.488	2
UniProt:Q96GQ5 RUS1			0.488	2
UniProt:O95159 ZFPL1			0.488	2
UniProt:Q96IV6 FXDC2			0.488	2
UniProt:O60883 GPR37L1	1	GPR37L1 [plasma membrane] (R-HSA-5336178)	0.488	2
UniProt:Q8N2M4 TM86A			0.488	2
UniProt:Q86W74-2 ANKRD46			0.488	2
UniProt:Q8IY49-2 MMD2			0.488	2
UniProt:P42857 NSG1			0.488	2
IntAct:EBI-12058603 CXCL16			0.488	2
UniProt:Q96HH6 TMM19			0.488	2
UniProt:Q9Y2E5 MAN2B2	1	MAN2B2 [lysosomal lumen] (R-HSA-6799575)	0.488	2
UniProt:Q6TCH4 PAQR6			0.488	2
UniProt:O75355-2 ENTPD3			0.488	2
UniProt:Q9UKR5 ERG28			0.488	2
UniProt:Q8WWP7 GIMA1			0.488	2
UniProt:Q96EC8 YIPF6	2	YIPF6 [cytoplasmic vesicle membrane] (R-HSA-434199) YIPF6 [Golgi membrane] (R-HSA-434346)	0.488	2
UniProt:Q14162 SCARF1	2	SCARF1 [plasma membrane] (R-HSA-2197636) SCARF1 [endocytic vesicle membrane] (R-HSA-2239453)	0.488	2
UniProt:Q7Z2K6 ERMP1			0.488	2
UniProt:O14880 MGST3	1	MGST3 [endoplasmic reticulum membrane] (R-HSA-176053)	0.488	2
UniProt:Q96CP7 TLCD1			0.488	2
UniProt:Q96G79 S35A4			0.488	2
UniProt:P19397 CD53	3	CD53 [plasma membrane] (R-HSA-6804817) CD53 [tertiary granule membrane] (R-HSA-6804799) CD53 [specific granule membrane] (R-HSA-6804793)	0.488	2
UniProt:Q969L2 MAL2			0.488	2
UniProt:Q9H0R3 TM222			0.488	2
UniProt:Q6UX06 OLFM4	3	OLFM4 [extracellular region] (R-HSA-6799672) OLFM4 [specific granule lumen] (R-HSA-6799634) OLFM4 [tertiary granule lumen] (R-HSA-6800893)	0.488	2
UniProt:Q9Y3E0 GOT1B			0.488	2
UniProt:P11215 ITGAM	3	ITGAM [specific granule membrane] (R-HSA-6799647) ITGAM [tertiary granule membrane] (R-HSA-6800979) ITGAM [plasma membrane] (R-HSA-202757)	0.488	2
UniProt:P41181 AQP2	3	p-S256-AQP2 [transport vesicle membrane] (R-HSA-432222) AQP2 [transport vesicle membrane] (R-HSA-432215) p-S256-AQP2 [plasma membrane] (R-HSA-432231)	0.488	2
UniProt:Q9H1C4 UNC93B1	4	UNC93B1 [endoplasmic reticulum membrane] (R-HSA-1678930) UNC93B1 [Golgi membrane] (R-HSA-1679064) UNC93B1 P345fs* [endoplasmic reticulum membrane] (R-HSA-9628866) UNC93B1 G261fs* [endoplasmic reticulum membrane] (R-HSA-9628869)	0.488	2
UniProt:P56557 TM50B			0.488	2
UniProt:Q02161-2 Q021612			0.488	2
UniProt:Q13277 STX3	1	STX3 [plasma membrane] (R-HSA-449131)	0.488	2
UniProt:Q9NUH8 TM14B			0.488	2
UniProt:Q12983 BNIP3			0.488	2
UniProt:P43378 PTPN9	1	PTPN9 [nucleoplasm] (R-HSA-9008907)	0.488	2
UniProt:P11169 SLC2A3	5	SLC2A3 [tertiary granule membrane] (R-HSA-6800180) SLC2A3 [secretory granule membrane] (R-HSA-6800892) SLC2A3 [ficolin-1-rich granule membrane] (R-HSA-6801040) SLC2A3 [specific granule membrane] (R-HSA-6800184) SLC2A3 [plasma membrane] (R-HSA-70407)	0.488	2
UniProt:O14653 GOSR2	4	GOSR2 [endoplasmic reticulum membrane] (R-HSA-5689451) GOSR2 [ER to Golgi transport vesicle membrane] (R-HSA-5689800) GOSR2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-535472) GOSR2 [Golgi membrane] (R-HSA-6807755)	0.488	2
UniProt:Q13183 SLC13A2	1	SLC13A2 [plasma membrane] (R-HSA-433093)	0.488	2
UniProt:Q9NPL8 TIMMDC1	1	TIMMDC1 [mitochondrial inner membrane] (R-HSA-5689720)	0.488	2
UniProt:Q14534 SQLE	1	SQLE [endoplasmic reticulum membrane] (R-HSA-191395)	0.488	2
UniProt:P05090 APOD	1	APOD [extracellular region] (R-HSA-5216199)	0.488	2
UniProt:Q7L5A8 FA2H	1	FA2H [endoplasmic reticulum membrane] (R-HSA-5693771)	0.488	2
UniProt:Q15848 ADIPOQ	1	ADIPOQ [extracellular region] (R-HSA-1183052)	0.488	2
UniProt:Q9NUQ2 AGPAT5	2	AGPAT5 [endoplasmic reticulum membrane] (R-HSA-61811) AGPAT5 [mitochondrial outer membrane] (R-HSA-1500585)	0.488	2
UniProt:P63027 VAMP2	23	VAMP2 [plasma membrane] (R-HSA-210516) VAMP2 [clathrin-sculpted monoamine transport vesicle membrane] (R-HSA-379363) VAMP2 [clathrin-sculpted glutamate transport vesicle membrane] (R-HSA-210365) VAMP2 [clathrin-sculpted glutamate transport vesicle membrane] (R-HSA-372517) VAMP2 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-917738) VAMP2 [synaptic vesicle membrane] (R-HSA-181517) VAMP2(59-116) [synaptic vesicle membrane] (R-HSA-5250891) VAMP2(2-58) [cytosol] (R-HSA-194815) VAMP2(2-76) [cytosol] (R-HSA-194802) VAMP2(77-116) [synaptic vesicle membrane] (R-HSA-5228355) VAMP2(60-116) [synaptic vesicle membrane] (R-HSA-5250615) VAMP2(2-59) [cytosol] (R-HSA-194797) VAMP2(82-116) [synaptic vesicle membrane] (R-HSA-5250961) VAMP2(2-81) [cytosol] (R-HSA-5250970) VAMP2 [secretory granule membrane] (R-HSA-265198) VAMP2 [cytosol] (R-HSA-9609882) VAMP2 [endoplasmic reticulum membrane] (R-HSA-9609886) VAMP2 [cytoplasmic vesicle membrane] (R-HSA-1449630) VAMP2 [lysosomal membrane] (R-HSA-432703) VAMP2 [Golgi membrane] (R-HSA-375425) VAMP2 [cytoplasmic vesicle membrane] (R-HSA-375436) VAMP2 [secretory granule membrane] (R-HSA-376363) VAMP2 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869129)	0.488	2
UniProt:O15155 BET1	3	BET1 [transport vesicle] (R-HSA-6808719) BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688142) BET1 [Golgi membrane] (R-HSA-6807743)	0.488	2
UniProt:Q9Y5Y5 PEX16	2	PEX16 [peroxisomal membrane] (R-HSA-9603805) PEX16 [cytosol] (R-HSA-9603790)	0.488	2
UniProt:P01375 TNF	5	TNF(1-34) [plasma membrane] (R-HSA-8863367) TNF(52-76) [extracellular region] (R-HSA-8863375) TNF(1-76) [plasma membrane] (R-HSA-8863120) TNF(77-233) [extracellular region] (R-HSA-976821) TNF(1-233) [plasma membrane] (R-HSA-66220)	0.488	2
UniProt:Q8WWT9 SLC13A3	1	SLC13A3 [plasma membrane] (R-HSA-433095)	0.488	2
UniProt:Q9UPQ8 DOLK	6	DOLK W304C [endoplasmic reticulum membrane] (R-HSA-4755557) DOLK Y441S [endoplasmic reticulum membrane] (R-HSA-4755590) DOLK C99S [endoplasmic reticulum membrane] (R-HSA-4755602) DOLK H408D [endoplasmic reticulum membrane] (R-HSA-4755548) DOLK M1I [endoplasmic reticulum membrane] (R-HSA-4755593) DOLK [endoplasmic reticulum membrane] (R-HSA-449274)	0.488	2
UniProt:Q15125 EBP	1	EBP [endoplasmic reticulum membrane] (R-HSA-195697)	0.488	2
UniProt:Q96AA3 RFT1	2	RFT1 [endoplasmic reticulum membrane] (R-HSA-449255) RFT1 R67C [endoplasmic reticulum membrane] (R-HSA-4570578)	0.488	2
UniProt:O75396 SEC22B	6	SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.488	2
UniProt:P21854 CD72	1	CD72 [plasma membrane] (R-HSA-198121)	0.488	2
UniProt:Q8IY26 PLPP6	1	PLPP6 [plasma membrane] (R-HSA-8952144)	0.488	2
UniProt:Q9BVK2 ALG8	5	ALG8 T47P [endoplasmic reticulum membrane] (R-HSA-4724334) ALG8 G275D [endoplasmic reticulum membrane] (R-HSA-4724304) ALG8 V133Sfs3 [endoplasmic reticulum membrane] (R-HSA-4724313) ALG8 T138Kfs19 [endoplasmic reticulum membrane] (R-HSA-4724312) ALG8 [endoplasmic reticulum membrane] (R-HSA-449640)	0.488	2
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.488	2
UniProt:Q9NTJ5 SACM1L	2	SACM1L [endoplasmic reticulum membrane] (R-HSA-1604637) SACM1L [Golgi membrane] (R-HSA-1806242)	0.488	2
UniProt:Q9Y5Z9 UBIAD1	1	UBIAD1 [endoplasmic reticulum membrane] (R-HSA-2980965)	0.488	2