TFAP2C homodimer binds the EGFR gene promoter

Stable Identifier
R-HSA-8874789
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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TFAP2C (AP-2 gamma) homodimer binds the promoter region of the EGFR gene (Park et al. 2015, De Andrade et al. 2016).

Literature References
PubMed ID Title Journal Year
25772240 The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis

Park, JM, Wu, T, Cyr, AR, Woodfield, GW, De Andrade, JP, Spanheimer, PM, Li, T, Sugg, SL, Lal, G, Domann, FE, Zhang, W, Weigel, RJ

Oncogene 2015
26832794 EGFR Is Regulated by TFAP2C in Luminal Breast Cancer and Is a Target for Vandetanib

De Andrade, JP, Park, JM, Gu, VW, Woodfield, GW, Kulak, MV, Lorenzen, AW, Wu, VT, Van Dorin, SE, Spanheimer, PM, Weigel, RJ

Mol. Cancer Ther. 2016
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