CREBRF binds CREB3

Stable Identifier
R-HSA-8874849
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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CREBRF (Luman recruitment factor, LRF) binds CREB3 in the nucleus and recruits CREB3 into nuclear foci (Audas et al. 2008). CREBRF destabilizes CREB3 and reduces the transcription activation activity of CREB3 during endoplasmic reticulum stress.

Literature References
PubMed ID Title Journal Year
18391022 A novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein response

Audas, TE, Li, Y, Liang, G, Lu, R

Mol. Cell. Biol. 2008
Participants
Participant Of
Orthologous Events
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Created