Reactome | RIN1 [cytosol]

RIN1 [cytosol]

Stable Identifier

R-HSA-8875287

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Ras and Rab interactor 1, RIN1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q13671 RIN1

Gene Names

RIN1

Chain

chain:1-783

Reference Genes

BioGPS Gene:9610 RIN1

COSMIC (genes):RIN1 RIN1

CTD Gene:9610 RIN1

dbSNP Gene:9610 RIN1

ENSEMBL:ENSG00000174791 RIN1

HGNC:18749 RIN1

Monarch:9610 RIN1

NCBI Gene:9610 RIN1

OMIM:605965 RIN1

UCSC:Q13671 RIN1

Reference Transcript

RefSeq:NM_004292.2 RIN1

Other Identifiers

11725895_a_at

11725896_x_at

11745059_a_at

11745060_x_at

11750946_x_at

11761664_x_at

11763334_at

16740728

1777_at

1778_g_at

205211_PM_s_at

205211_s_at

3378192

3378193

3378194

3378195

3378196

3378197

3378198

3378199

3378200

3378201

3378202

3378203

3378204

3378205

3378206

3378207

3378208

3378209

39532_at

7949592

9610

A_23_P64102

A_33_P3266010

GE58330

GO:0005085

GO:0005096

GO:0005515

GO:0005737

GO:0005829

GO:0005856

GO:0005886

GO:0006897

GO:0007165

GO:0016020

GO:0016192

GO:0030139

GO:0031267

GO:0031410

GO:0043226

GO:0098772

HMNXSV003024088

ILMN_1660858

L36463_at

PH_hs_0000133

TC11001963.hg

g4759039_3p_at

g4759039_3p_x_at

Participates

as a member of

RAB5 GEFs [cytosol] (Homo sapiens)

Inferred To

vps901 [cytosol] (Schizosaccharomyces pombe)

rin-1 [cytosol] (Caenorhabditis elegans)

Homologues of RIN1 [cytosol] (Dictyostelium discoideum)

Homologues of RIN1 [cytosol] (Plasmodium falciparum)

Homologues of RIN1 [cytosol] (Saccharomyces cerevisiae)

Homologues of RIN1 [cytosol] (Schizosaccharomyces pombe)

MUK1 [cytosol] (Saccharomyces cerevisiae)

BRMS1 [cytosol] (Bos taurus)

spri [cytosol] (Drosophila melanogaster)

vps902 [cytosol] (Schizosaccharomyces pombe)

RIN1 [cytosol] (Canis familiaris)

RIN1 [cytosol] (Dictyostelium discoideum)

RIN1 [cytosol] (Plasmodium falciparum)

Rin1 [cytosol] (Mus musculus)

Rin1 [cytosol] (Rattus norvegicus)

VPS9 [cytosol] (Saccharomyces cerevisiae)

Cross References

ENSEMBL

ENST00000311320, ENSP00000310406

OpenTargets

ENSG00000174791

HPA

ENSG00000174791-RIN1

PRO

Q13671

Pharos - Targets

Q13671

HMDB Protein

HMDBP08556

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00519 ABL1	6	p-S456-ABL1 [nucleoplasm] (R-HSA-5686576) ABL1 [nucleoplasm] (R-HSA-5686579) p-Y226,Y393-ABL1 [cytosol] (R-HSA-8942610) ABL1 [cytosol] (R-HSA-375987) p-Y226,Y393-ABL1 [nucleoplasm] (R-HSA-8985251) p-Y393-ABL1 [cytosol] (R-HSA-9865161)	0.786	6
UniProt:P42684 ABL2	1	ABL2 [cytosol] (R-HSA-375998)	0.748	6
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.738	4
UniProt:Q86TI0 TBC1D1	2	TBC1D1 [cytoplasmic vesicle membrane] (R-HSA-1454718) p-S237-TBC1D1 [cytosol] (R-HSA-1454673)	0.556	3
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [plasma membrane] (R-HSA-416989) PICK1 [endocytic vesicle membrane] (R-HSA-417017)	0.556	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.556	3
UniProt:O96006 ZBED1	1	ZBED1 [nucleoplasm] (R-HSA-8956376)	0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199)	0.556	3
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.527	2
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.463	3

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