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ALS2 [cytosol]
Stable Identifier
R-HSA-8875298
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Alsin, ALS2_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 GEFs activate RAC1 (Homo sapiens)
RAC1 GEFs [cytosol] (Homo sapiens)
ALS2 [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
RAB5 GEFs exchange GTP for GDP on RAB5 (Homo sapiens)
RAB5 GEFs [cytosol] (Homo sapiens)
ALS2 dimer [cytosol] (Homo sapiens)
ALS2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96Q42 ALS2
Gene Names
ALS2, ALS2CR6, KIAA1563
Chain
chain:1-1657
Reference Genes
BioGPS Gene:57679 ALS2
COSMIC (genes):ALS2 ALS2
CTD Gene:57679 ALS2
dbSNP Gene:57679 ALS2
ENSEMBL:ENSG00000003393 ALS2
ENSEMBL_homo_sapiens_GENE:ENSG00000003393.16 ALS2
HGNC:443 ALS2
KEGG Gene (Homo sapiens):57679 ALS2
Monarch:57679 ALS2
NCBI Gene:57679 ALS2
OMIM:606352 ALS2
UCSC:Q96Q42 ALS2
Reference Transcript
RefSeq:NM_020919.3 ALS2
RefSeq:XM_006712654.2 ALS2
RefSeq:NM_001135745.1 ALS2
Other Identifiers
11719649_at
11730691_s_at
11750622_a_at
16907353
226291_PM_at
226291_at
232184_PM_at
232184_at
2595039
2595041
2595043
2595044
2595045
2595047
2595048
2595049
2595050
2595052
2595053
2595055
2595056
2595058
2595059
2595062
2595063
2595064
2595065
2595066
2595067
2595068
2595069
2595070
2595072
2595073
2595075
2595079
2595083
2595084
2595087
2595088
2595090
2595091
2595092
2595093
2595094
2595095
2595096
2595097
2595098
2595103
2595104
2595116
2595117
2595118
2595119
2595120
2595124
46359_at
51167_at
57679
80552_at
8058295
A_23_P209430
A_23_P377664
A_24_P222410
A_33_P3415345
GE541424
GE79204
GO:0001662
GO:0001726
GO:0001881
GO:0005085
GO:0005096
GO:0005515
GO:0005634
GO:0005737
GO:0005768
GO:0005769
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0006979
GO:0007032
GO:0007041
GO:0007528
GO:0007626
GO:0008104
GO:0014069
GO:0016050
GO:0016192
GO:0016197
GO:0023052
GO:0030027
GO:0030154
GO:0030425
GO:0030426
GO:0031267
GO:0031410
GO:0031982
GO:0032991
GO:0034330
GO:0035022
GO:0035249
GO:0036211
GO:0042802
GO:0042803
GO:0043197
GO:0043226
GO:0043231
GO:0043539
GO:0043547
GO:0045860
GO:0048812
GO:0048856
GO:0051036
GO:0051260
GO:0065003
GO:0098772
GO:0110165
HMNXSV003046024
HMNXSV003050323
Hs.149391.0.S1_3p_at
Hs.27669.0.S1_3p_at
ILMN_1750256
PH_hs_0002446
TC02002678.hg
Participates
as a component of
ALS2 dimer [cytosol] (Homo sapiens)
as a candidate of
RAC1 GEFs [cytosol] (Homo sapiens)
Inferred To
ALS2 [cytosol]
(Bos taurus)
ALS2 [cytosol]
(Canis familiaris)
ALS2 [cytosol]
(Gallus gallus)
ALS2 [cytosol]
(Sus scrofa)
Als2 [cytosol]
(Drosophila melanogaster)
Als2 [cytosol]
(Mus musculus)
Als2 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
XP_006712717.1
,
NP_001129217.1
,
NP_065970.2
OpenTargets
ENSG00000003393
GeneCards
Q96Q42
HPA
ENSG00000003393-ALS2
Ensembl
ENSP00000264276
,
ENSG00000003393
,
ENST00000467448
,
ENST00000680861
,
ENSP00000505187
,
ENST00000680163
,
ENSP00000386384
,
ENST00000264276
,
ENSP00000429223
,
ENST00000680188
,
ENST00000679516
,
ENST00000409632
,
ENSP00000505218
,
ENSP00000505968
,
ENSP00000505043
,
ENSP00000505665
,
ENST00000679435
,
ENSP00000505092
,
ENST00000679503
PRO
Q96Q42
Pharos - Targets
Q96Q42
Orphanet
15505
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.688
3
UniProt:P63104 YWHAZ
2
YWHAZ [nucleoplasm]
(R-HSA-450469)
YWHAZ [cytosol]
(R-HSA-206099)
0.527
2
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