Reactome | GGA3 [recycling endosome membrane]

GGA3 [recycling endosome membrane]

Stable Identifier

R-HSA-8875655

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

recycling endosome membrane

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NZ52 GGA3

Gene Names

GGA3, KIAA0154

Chain

chain:1-723

Reference Genes

BioGPS Gene:23163 GGA3

COSMIC (genes):GGA3 GGA3

CTD Gene:23163 GGA3

dbSNP Gene:23163 GGA3

ENSEMBL:ENSG00000125447 GGA3

HGNC:17079 GGA3

KEGG:hsa:23163 GGA3

Monarch:23163 GGA3

NCBI Gene:23163 GGA3

OMIM:606006 GGA3

UCSC:Q9NZ52 GGA3

Reference Transcript

Other Identifiers

11734365_a_at

11739388_a_at

11746601_a_at

11746602_a_at

11749714_a_at

11761151_a_at

16848761

209411_PM_s_at

209411_s_at

211815_PM_s_at

211815_s_at

23163

3770660

3770662

3770664

3770665

3770666

3770667

3770668

3770669

3770670

3770671

3770672

3770673

3770674

3770675

3770676

3770677

3770678

3770679

3770680

3770681

3770682

3770683

3770684

3770685

3770688

3770689

3770691

3770697

3770698

37959_at

8018324

A_23_P38181

D63876_at

GE57281

GO:0005215

GO:0005515

GO:0005764

GO:0005768

GO:0005773

GO:0005794

GO:0005802

GO:0006622

GO:0006886

GO:0006893

GO:0008289

GO:0010008

GO:0015031

GO:0016020

GO:0016192

GO:0030163

GO:0031267

GO:0031410

GO:0031647

GO:0031648

GO:0031901

GO:0032991

GO:0034394

GO:0035091

GO:0043001

GO:0043130

GO:0043226

GO:0044877

GO:0045732

GO:0055038

GO:0061462

GO:0072659

GO:0097708

GO:0140318

GO:1902430

GO:1905167

HMNXSV003022368

HMNXSV003058392

Hs.87726.0.S2_3p_a_at

ILMN_1675982

ILMN_1751135

ILMN_2402972

PH_hs_0004921

TC17001874.hg

TC17002786.hg

g7229485_3p_a_at

Participates

as a component of

HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL:GGA3:ARF6:GTP [recycling endosome membrane] (Homo sapiens)

Other forms of this molecule

GGA3 [endosome membrane]

GGA3 [early endosome membrane]

Inferred To

apt-9 [recycling endosome membrane] (Caenorhabditis elegans)

GGA3 [recycling endosome membrane] (Bos taurus)

GGA3 [recycling endosome membrane] (Canis familiaris)

GGA3 [recycling endosome membrane] (Gallus gallus)

GGA3 [recycling endosome membrane] (Sus scrofa)

Gga3 [recycling endosome membrane] (Mus musculus)

Gga3 [recycling endosome membrane] (Rattus norvegicus)

gga3 [recycling endosome membrane] (Xenopus tropicalis)

Cross References

OpenTargets

ENSG00000125447

ENSEMBL

ENSP00000438085, ENST00000649398, ENST00000537686, ENSP00000446421, ENST00000538886, ENST00000578348, ENSP00000463288, ENSP00000462081, ENSP00000496890, ENST00000582717

HPA

ENSG00000125447-GGA3

PRO

Q9NZ52

Pharos - Targets

Q9NZ52

GlyGen

Q9NZ52

PDB

1WR6, 1JPL, 1JUQ, 1LF8, 1YD8, 1P4U

HMDB Protein

HMDBP08422

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P11717 IGF2R	7	IGF2R [secretory granule membrane] (R-HSA-6803320) IGF2R [plasma membrane] (R-HSA-6806532) IGF2R [trans-Golgi network membrane] (R-HSA-6814608) IGF2R [transport vesicle] (R-HSA-6814609) IGF2R [cytoplasmic vesicle membrane] (R-HSA-434213) IGF2R [Golgi membrane] (R-HSA-434345) IGF2R [clathrin-coated endocytic vesicle membrane] (R-HSA-8869091)	0.761	8
UniProt:Q15276 RABEP1	1	RABEP1 [early endosome membrane] (R-HSA-2029004)	0.698	12
UniProt:P84080	2	ARF1 [cytosol] (R-BTA-200826) ARF1 [Golgi membrane] (R-BTA-199971)	0.646	3
UniProt:Q13258 PTGDR	1	PTGDR [plasma membrane] (R-HSA-391830)	0.61	5
UniProt:P62330 ARF6	2	ARF6 [recycling endosome membrane] (R-HSA-2029049) ARF6 [cytosol] (R-HSA-8871121)	0.589	3
UniProt:P20645 M6PR	6	M6PR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869100) M6PR [plasma membrane] (R-HSA-8864564) M6PR [Golgi membrane] (R-HSA-429824) M6PR [lysosomal membrane] (R-HSA-432696) M6PR [trans-Golgi network membrane] (R-HSA-6814611) M6PR [transport vesicle] (R-HSA-6814613)	0.573	2
UniProt:P56817 BACE1	8	BACE1 [endoplasmic reticulum lumen] (R-HSA-6783326) 7K-BACE1 [endoplasmic reticulum lumen] (R-HSA-5693006) BACE1(22-45) [Golgi-associated vesicle lumen] (R-HSA-5693069) 7K-BACE1 [Golgi-associated vesicle lumen] (R-HSA-5693095) 7K-BACE1(46-501) [Golgi-associated vesicle lumen] (R-HSA-5693106) BACE1(46-501) [Golgi-associated vesicle lumen] (R-HSA-5693105) BACE1(46-501) [plasma membrane] (R-HSA-5692933) BACE1 [endosome membrane] (R-HSA-5692942)	0.544	2
UniProt:Q6VY07 PACS1	1	PACS1 [cytosol] (R-HSA-167634)	0.544	5
UniProt:P18272 NCAP			0.524	2
UniProt:P0CG47 UBB	20	UBB(77-152) [endocytic vesicle membrane] (R-HSA-939253) UBB(1-76) [endocytic vesicle membrane] (R-HSA-939231) UBB(153-228) [endocytic vesicle membrane] (R-HSA-939171) Ub-33-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783023) Ub-109-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783008) Ub-185-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783046) Ub-215-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783002) Ub-63-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783148) Ub-139-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783012) Ub-158-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783162) Ub-6-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783014) Ub-82-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783015) Ub-163-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783025) Ub-87-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6782998) Ub-11-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783109) Ub-124-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783131) Ub-200-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783100) Ub-48-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783165) Ub-181-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783160) Ub-29-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783070)	0.508	2
UniProt:Q9UJY5 GGA1	2	GGA1 [early endosome membrane] (R-HSA-8854136) GGA1 [endosome membrane] (R-HSA-5692930)	0.508	4
UniProt:Q9UJY4 GGA2	2	GGA2 [early endosome membrane] (R-HSA-8854140) GGA2 [endosome membrane] (R-HSA-5692937)	0.508	3

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