InlB-activated MET phosphorylates CBL

Stable Identifier
R-HSA-8876246
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Listeria monocytogenes
Compartment
ReviewStatus
5/5
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Binding of InlB to MET receptor induces CBL phosphorylation on tyrosine residue(s). Based on the analogy with HGF-induced MET signaling, MET receptor activated by binding of the Listeria monocytogenes protein InlB phosphorylates CBL, promoting stronger interaction of CBL with MET (Peschard et al. 2001, Petrelli et al. 2002).
Participants
Participates
Catalyst Activity

protein tyrosine kinase activity of InlB:p-4Y-MET dimer:GRB2-1:CBL [plasma membrane]

Inferred From
Disease
Name Identifier Synonyms
listeriosis DOID:11573 Infection by Listeria monocytogenes, Infection due to Listeria monocytogenes, Listeria infection, Listeriosis
Authored
Reviewed
Created
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