Reactome | METTL21A [nucleoplasm]

METTL21A [nucleoplasm]

Stable Identifier

R-HSA-8876682

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Protein N-lysine methyltransferase METTL21A ecNumber2.1.1.-/ecNumber, MT21A_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q8WXE1 ATRIP

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External Reference Information

External Reference

UniProt:Q8WXB1 METTL21A

Gene Names

METTL21A, FAM119A, HCA557B

Chain

chain:1-218

Reference Genes

BioGPS Gene:151194 METTL21A

COSMIC (genes):METTL21A METTL21A

CTD Gene:151194 METTL21A

dbSNP Gene:151194 METTL21A

ENSEMBL:ENSG00000144401 METTL21A

HGNC:30476 METTL21A

Monarch:151194 METTL21A

NCBI Gene:151194 METTL21A

OMIM:615257 METTL21A

UCSC:Q8WXB1 METTL21A

Reference Transcript

Other Identifiers

11758563_at

151194

1553743_PM_at

1553743_at

16907672

235177_PM_at

235177_at

235931_PM_at

235931_at

2402941

2596690

2596691

2596692

2596693

2596694

2596703

2596704

2596705

2596706

2596710

2596711

2596712

2596713

2596714

2596715

2596716

2596717

2596718

2596719

2596720

2596721

2596722

2854785

3622687

3856987

80579_at

8058486

81885_at

83606_at

A_23_P209337

A_24_P162929

A_24_P854913

GE79455

GO:0003824

GO:0005515

GO:0005654

GO:0005737

GO:0005829

GO:0006325

GO:0006338

GO:0006479

GO:0008168

GO:0008276

GO:0016279

GO:0016740

GO:0018022

GO:0030544

GO:0031072

GO:0032259

GO:0032991

GO:0042054

GO:0051117

GO:0140096

HMNXSV003049566

Hs.125757.0.A1_3p_at

Hs.149596.0.A1_3p_at

Hs2.352294.1.S1_3p_at

ILMN_1762888

ILMN_2049364

PH_hs_0017058

Inferred To

METTL21A [nucleoplasm] (Bos taurus)

METTL21A [nucleoplasm] (Canis familiaris)

METTL21A [nucleoplasm] (Danio rerio)

METTL21A [nucleoplasm] (Dictyostelium discoideum)

METTL21A [nucleoplasm] (Gallus gallus)

METTL21A [nucleoplasm] (Mus musculus)

METTL21A [nucleoplasm] (Saccharomyces cerevisiae)

METTL21A [nucleoplasm] (Schizosaccharomyces pombe)

METTL21A [nucleoplasm] (Sus scrofa)

METTL21A [nucleoplasm] (Xenopus tropicalis)

Mettl21a [nucleoplasm] (Rattus norvegicus)

Cross References

OpenTargets

ENSG00000144401

ENSEMBL

ENSP00000400730, ENSP00000389684, ENSP00000403317, ENSP00000385481, ENSP00000392062, ENSP00000407622, ENST00000411432, ENST00000406927, ENST00000458426, ENSP00000415115, ENST00000448007, ENST00000426075, ENST00000442521, ENST00000425132

HPA

ENSG00000144401-METTL21A

PRO

Q8WXB1

Pharos - Targets

Q8WXB1

PDB

4LEC

Interactors (16)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8IZ13 F200C			0.742	8
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.666	4
UniProt:Q8IXL7-2 MSRB3			0.556	3
UniProt:Q9UGI0 ZRANB1	1	ZRANB1 [cytosol] (R-HSA-6781939)	0.556	3
UniProt:Q8WXE1 ATRIP	1	ATRIP [nucleoplasm] (R-HSA-176231)	0.556	3
UniProt:Q8N720 ZNF655	1	ZNF655 [nucleoplasm] (R-HSA-2127575)	0.556	3
UniProt:A8MW99 MEI4			0.556	3
UniProt:Q6ZNG0 ZNF620	1	ZNF620 [nucleoplasm] (R-HSA-2127603)	0.556	3
UniProt:Q99471 PFDN5	1	PFDN5 [cytosol] (R-HSA-379548)	0.556	3
UniProt:Q6FHY5 Q6FHY5			0.556	3
UniProt:P59998 ARPC4	1	ARPC4 [cytosol] (R-HSA-200813)	0.556	3
UniProt:Q9Y250 LZTS1			0.556	3
UniProt:O95817 BAG3	1	BAG3 [cytosol] (R-HSA-5255451)	0.527	3
UniProt:P34932 HSPA4	2	HSPA4 [cytosol] (R-HSA-5251946) HSPA4 [nucleoplasm] (R-HSA-5251998)	0.527	3
UniProt:Q9NZL4 HPBP1			0.527	2
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.527	3

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