RUNX3 binds ZFHX3

Stable Identifier
R-HSA-8878117
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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In response to TGF-beta (TGFB1) signaling, RUNX3 binds to the homeobox transcription factor and tumor suppressor ZFHX3 (ATBF1). The exact mechanism and regulation of RUNX3 and ATBF1 binding is not known (Mabuchi et al. 2010).

Literature References
PubMed ID Title Journal Year
20599712 Tumor suppressor, AT motif binding factor 1 (ATBF1), translocates to the nucleus with runt domain transcription factor 3 (RUNX3) in response to TGF-beta signal transduction

Mabuchi, M, Kataoka, H, Miura, Y, Kim, TS, Kawaguchi, M, Ebi, M, Tanaka, M, Mori, Y, Kubota, E, Mizushima, T, Shimura, T, Mizoshita, T, Tanida, S, Kamiya, T, Asai, K, Joh, T

Biochem. Biophys. Res. Commun. 2010
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