Reuptake of GABA

Stable Identifier
R-HSA-888593
Type
Pathway
Species
Homo sapiens
Compartment
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General
SVG |   | PPTX  | SBGN
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Reuptake of GABA from the synapse terminates the action of GABA thus regulating GABA action. GABA taken up from the synapse into the neurons is reused for synaptic loading. GABA taken up by astrocytes is degraded into C02 and glutamine. Glutamine is transported into the neurons for glutamate and GABA synthesis.

Literature References
PubMed ID Title Journal Year
19924586 Effects of the GABA-reuptake inhibitor tiagabine on panic and anxiety in patients with panic disorder

Zwanzger, P, Eser, D, Nothdurfter, C, Baghai, TC, Möller, HJ, Padberg, F, Rupprecht, R

Pharmacopsychiatry 2009
Participants
Participant Of
Orthologous Events
Cross References
BioModels Database
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Created