Reactome | WDR61 [cytosol]

WDR61 [cytosol]

Stable Identifier

R-HSA-8931534

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

WD repeat-containing protein 61, WDR61_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9GZS3 WDR61

Gene Names

WDR61

Chain

initiator methionine:1, chain:1-305, chain:2-305

Reference Genes

BioGPS Gene:80349 WDR61

COSMIC (genes):WDR61 WDR61

CTD Gene:80349 WDR61

dbSNP Gene:80349 WDR61

ENSEMBL:ENSG00000140395 WDR61

HGNC:30300 WDR61

KEGG Gene (Homo sapiens):80349 WDR61

Monarch:80349 WDR61

NCBI Gene:80349 WDR61

OMIM:609540 WDR61

UCSC:Q9GZS3 WDR61

Reference Transcript

Other Identifiers

0001240592

11757639_a_at

16812142

221531_at

221532_s_at

232075_at

3634595

3634596

3634597

3634599

3634602

3634604

3634606

3634607

3634608

3634612

3634613

3634616

3634619

3634621

3634622

3634625

3634626

7990700

80349

90320_at

GE56402

GE79470

GO:0002376

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0006366

GO:0006368

GO:0006464

GO:0007165

GO:0007267

GO:0008150

GO:0009056

GO:0009058

GO:0016055

GO:0016567

GO:0016593

GO:0030154

GO:0032991

GO:0034641

GO:0034655

GO:0035327

GO:0043226

GO:0043928

GO:0045638

GO:0048856

GO:0051276

GO:0051571

GO:0055087

GO:0080182

GO:2001162

Hs.306765.0.S1_3p_at

ILMN_1665887

PH_hs_0022380

TC15001703.hg

g11139241_3p_s_at

Participant Of

hasComponent

SKI complex [cytosol]

Other forms of this molecule

WDR61 [nucleoplasm]

Inferred To

Wdr61 [cytosol] (Mus musculus)

Wdr61 [cytosol] (Rattus norvegicus)

SKI8 [cytosol] (Saccharomyces cerevisiae)

WDR61 [cytosol] (Caenorhabditis elegans)

WDR61 [cytosol] (Canis familiaris)

WDR61 [cytosol] (Gallus gallus)

WDR61 [cytosol] (Sus scrofa)

Dmel\CG3909 [cytosol] (Drosophila melanogaster)

wdr61 [cytosol] (Danio rerio)

wdr61 [cytosol] (Dictyostelium discoideum)

wdr61 [cytosol] (Xenopus tropicalis)

rec14 [cytosol] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_001290177.1, XP_011520396.1, NP_079510.1, NP_001290176.1

OpenTargets

ENSG00000140395

HPA

ENSG00000140395-WDR61

GeneCards

Q9GZS3

Ensembl

ENSG00000140395, ENST00000558311, ENST00000267973, ENSP00000453801, ENSP00000267973

PRO

Q9GZS3

Orphanet

28708

PDB

6TED, 3OW8, 6GMH

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6P1J9 CDC73	1	CDC73 [nucleoplasm] (R-HSA-3322360)	0.864	11
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.666	22
UniProt:Q8WVC0 LEO1	1	LEO1 [nucleoplasm] (R-HSA-3322361)	0.643	5
UniProt:P14136 GFAP	3	GFAP [lysosomal membrane] (R-HSA-9625195) p-GFAP [lysosomal membrane] (R-HSA-9626054) GFAP [cytosol] (R-HSA-1253311)	0.556	3
UniProt:P05067 APP	20	APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3
UniProt:P51149 RAB7A	7	GGC-RAB7A [cytosol] (R-HSA-8870438) GGC-RAB7A [lysosomal membrane] (R-HSA-8877454) RAB7A [lysosomal membrane] (R-HSA-2213231) RAB7A [phagocytic vesicle membrane] (R-HSA-9636586) RAB7A [cytosol] (R-HSA-8870415) RAB7A [plasma membrane] (R-HSA-6804990) RAB7A [secretory granule membrane] (R-HSA-6804969)	0.556	3
UniProt:Q99497 PARK7	7	PARK7 [nucleoplasm] (R-HSA-3900141) SUMO1-K130-PARK7 [nucleoplasm] (R-HSA-4085351) PolyUb-Misfolded PARK7 [late endosome lumen] (R-HSA-9660005) Misfolded PARK7 [cytosol] (R-HSA-9641100) Ub-Misfolded PARK7 [cytosol] (R-HSA-9641123) PolyUb-Misfolded PARK7 [cytosol] (R-HSA-9641128) PolyUb-Misfolded PARK7 [lysosomal lumen] (R-HSA-9659997)	0.556	3
UniProt:Q16143 SNCB	1	SNCB [cytosol] (R-HSA-5660390)	0.556	3
UniProt:P29474 NOS3	7	MyrG-NOS3 [Golgi membrane] (R-HSA-534995) 2xPalmC-MyrG-NOS3 [endocytic vesicle membrane] (R-HSA-535007) MyrG-NOS3 [cytosol] (R-HSA-203687) 2xPalmC-MyrG-NOS3 [Golgi membrane] (R-HSA-203769) 2xPalmC-MyrG-NOS3 [plasma membrane] (R-HSA-534993) 2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (R-HSA-202139) NOS3 [cytosol] (R-HSA-202114)	0.556	3
UniProt:P00441 SOD1	5	2xHC-SOD1 [mitochondrial intermembrane space] (R-HSA-3777108) SOD1 [extracellular region] (R-HSA-350705) SOD1 [mitochondrial intermembrane space] (R-HSA-3777082) SOD1 [cytosol] (R-HSA-350697) 2xHC-SOD1 [cytosol] (R-HSA-3299726)	0.556	3
UniProt:P02545-2 LMNA	5	p-S22, S395-LMNA-2 [nucleoplasm] (R-HSA-5229019) LMNA-2 [nuclear envelope] (R-HSA-912378) p-S395-LMNA-2 [nucleoplasm] (R-HSA-5228740) Lamin C [nucleoplasm] (R-HSA-264872) LMNA-2 [cytosol] (R-HSA-2995387)	0.556	3
UniProt:P19404 NDUFV2	1	NDUFV2 [mitochondrial inner membrane] (R-HSA-163939)	0.556	3
UniProt:Q53GS7 GLE1	1	GLE1 [nucleoplasm] (R-HSA-8932905)	0.556	3
UniProt:P37840 SNCA	4	SNCA [extracellular region] (R-HSA-976954) SNCA A30P [cytosol] (R-HSA-5658569) SNCA [cytosol] (R-HSA-5658500) Ub-SNCA [cytosol] (R-HSA-5660754)	0.556	3

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