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UCN(83-122) [extracellular region]
Stable Identifier
R-HSA-8931580
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Urocortin, UCN1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Peptide hormone metabolism (Homo sapiens)
Synthesis, secretion, and deacylation of Ghrelin (Homo sapiens)
Expression of Preproghrelin (Homo sapiens)
CRHR2:UCN(83-122) [plasma membrane] (Homo sapiens)
UCN(83-122) [extracellular region] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class B/2 (Secretin family receptors) (Homo sapiens)
CRHR1,CRHR2-1 binds CRH,UCN (Homo sapiens)
CRH,UCN [extracellular region] (Homo sapiens)
UCN(83-122) [extracellular region] (Homo sapiens)
CRHR1,CRHR2-1:CRH,UCN [plasma membrane] (Homo sapiens)
CRH,UCN [extracellular region] (Homo sapiens)
UCN(83-122) [extracellular region] (Homo sapiens)
CRHR2-2 binds CRH,UCN,UCN2,UCN3 (Homo sapiens)
CRH,UCN,UCN2,UCN3 [extracellular region] (Homo sapiens)
UCN(83-122) [extracellular region] (Homo sapiens)
CRHR2-2:CRH,UCN,UCN2,UCN3 [plasma membrane] (Homo sapiens)
CRH,UCN,UCN2,UCN3 [extracellular region] (Homo sapiens)
UCN(83-122) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P55089 UCN
Gene Names
UCN
Chain
signal peptide:1-25, propeptide:26-82, peptide:83-122
Reference Genes
BioGPS Gene:7349 UCN
COSMIC (genes):UCN UCN
CTD Gene:7349 UCN
dbSNP Gene:7349 UCN
ENSEMBL:ENSG00000163794 UCN
ENSEMBL_homo_sapiens_GENE:ENSG00000163794.6 UCN
HGNC:12516 UCN
KEGG Gene (Homo sapiens):7349 UCN
Monarch:7349 UCN
NCBI Gene:7349 UCN
OMIM:600945 UCN
UCSC:P55089 UCN
Reference Transcript
RefSeq:NM_003353.3 UCN
Other Identifiers
11715234_s_at
11759524_at
16895739
206072_PM_at
206072_at
2545646
2545647
2545648
2545649
2545650
2545652
37853_at
7349
8051061
A_24_P62883
A_33_P3353030
GE81267
GE85501
GO:0001664
GO:0001934
GO:0001964
GO:0003012
GO:0003013
GO:0005179
GO:0005184
GO:0005515
GO:0005576
GO:0006091
GO:0006260
GO:0006351
GO:0006355
GO:0006979
GO:0007186
GO:0007218
GO:0007565
GO:0007605
GO:0007611
GO:0007631
GO:0008306
GO:0009060
GO:0010628
GO:0010629
GO:0010996
GO:0012501
GO:0022414
GO:0023052
GO:0030154
GO:0030307
GO:0030424
GO:0030425
GO:0031175
GO:0032099
GO:0032355
GO:0032755
GO:0032967
GO:0033138
GO:0035176
GO:0036211
GO:0042311
GO:0042756
GO:0043025
GO:0043066
GO:0043117
GO:0043196
GO:0043204
GO:0043524
GO:0043679
GO:0043950
GO:0045727
GO:0045740
GO:0045776
GO:0045792
GO:0045944
GO:0046811
GO:0046888
GO:0048018
GO:0048265
GO:0048856
GO:0050877
GO:0050886
GO:0051384
GO:0051430
GO:0051431
GO:0051461
GO:0051966
GO:0060452
GO:0090280
GO:0098772
GO:2000252
GO:2000987
HMNXSV003046166
ILMN_1707258
ILMN_2084073
PH_hs_0008132
TC02001680.hg
U43177_at
g12056477_3p_at
Participates
as a member of
CRH,UCN,UCN2,UCN3 [extracellular region] (Homo sapiens)
CRH,UCN [extracellular region] (Homo sapiens)
as a component of
CRHR2:UCN(83-122) [plasma membrane] (Homo sapiens)
Inferred To
Ucn [extracellular region]
(Mus musculus)
Ucn [extracellular region]
(Rattus norvegicus)
UCN [extracellular region]
(Canis familiaris)
UCN [extracellular region]
(Sus scrofa)
LOC121110414 [extracellular region]
(Gallus gallus)
Cross References
RefSeq
NP_003344.1
OpenTargets
ENSG00000163794
GeneCards
P55089
HPA
ENSG00000163794-UCN
Ensembl
ENST00000296099
,
ENSG00000163794
,
ENSP00000296099
PRO
P55089
Pharos - Targets
P55089
PDB
3N96
,
6PB0
,
6PB1
,
2RMF
,
7TS0
,
7TRY
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P06850 CRH
1
CRH [extracellular region]
(R-HSA-420146)
0.544
2
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