ESR1 binds the AXIN1 gene

Stable Identifier
R-HSA-8932070
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Estrogen receptor alpha (ESR1) binds to estrogen response elements in the second intron of the AXIN1 gene (Chimge et al. 2016).

Literature References
PubMed ID Title Journal Year
26916619 RUNX1 prevents oestrogen-mediated AXIN1 suppression and β-catenin activation in ER-positive breast cancer

Chimge, NO, Little, GH, Baniwal, SK, Adisetiyo, H, Xie, Y, Zhang, T, O'Laughlin, A, Liu, ZY, Ulrich, P, Martin, A, Mhawech-Fauceglia, P, Ellis, MJ, Tripathy, D, Groshen, S, Liang, C, Li, Z, Schones, DE, Frenkel, B

Nat Commun 2016
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