METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8

Stable Identifier
R-HSA-8932221
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
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Protein N-lysine methyltransferase METTL21A trimethylates lysine-561 of Heat shock cognate 71 kDa protein (HSPA8) and corresponding lysine residues in other Hsp70 isoforms (Jakobsson et al. 2013, Cloutier et al. 2013).

Literature References
PubMed ID Title Journal Year
23349634 A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity

Cloutier, P, Lavallée-Adam, M, Faubert, D, Blanchette, M, Coulombe, B

PLoS Genet. 2013
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein-lysine N-methyltransferase activity of METTL21A [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created