METTL22 transfers 3xCH3 from 3xAdoMet to KIN

Stable Identifier
R-HSA-8932275
Type
Reaction
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
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Summation

METTL22 trimethylates lysine-135 of DNA/RNA-binding protein KIN17 (KIN) (Cloutier et al. 2013)

Literature References
PubMed ID Title Journal Year
23349634 A newly uncovered group of distantly related lysine methyltransferases preferentially interact with molecular chaperones to regulate their activity

Cloutier, P, Lavallée-Adam, M, Faubert, D, Blanchette, M, Coulombe, B

PLoS Genet. 2013
Participants
Input
Output
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
protein-lysine N-methyltransferase activity of METTL22 [nucleoplasm]
Physical Entity
METTL22 [nucleoplasm]
Activity
protein-lysine N-methyltransferase activity (0016279)
Orthologous Events
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Arabidopsis thaliana)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Bos taurus)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Canis familiaris)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Danio rerio)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Drosophila melanogaster)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Gallus gallus)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Mus musculus)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Oryza sativa)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Rattus norvegicus)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Sus scrofa)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Taeniopygia guttata)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Xenopus tropicalis)
Authored
Jupe, S  (2016-06-16)
Reviewed
Falnes, PØ  (2016-10-10)