VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP

Stable Identifier
R-HSA-8932276
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP
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Protein N-lysine methyltransferase METTL21D (VCPKMT) trimethylates lysine-315 of VCP (Kernstock et al. 2012, Cloutier et al. 2013).
Literature References
PubMed ID Title Journal Year
16118227 Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase

Sun, XJ, Wei, J, Wu, XY, Hu, M, Wang, L, Wang, HH, Zhang, QH, Chen, SJ, Huang, QH, Chen, Z

J. Biol. Chem. 2005
Participants
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Output
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as an event of
Catalyst Activity

protein-lysine N-methyltransferase activity of VCPKMT [cytosol]

Physical Entity
VCPKMT [cytosol] (Homo sapiens)
Activity
protein-lysine N-methyltransferase activity (GO:0016279)
Orthologous Events
VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Canis familiaris)
VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Danio rerio)
VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Dictyostelium discoideum)
VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Gallus gallus)
VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Mus musculus)
VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Saccharomyces cerevisiae)
VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Schizosaccharomyces pombe)
VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Sus scrofa)
VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Xenopus tropicalis)
Authored
Jupe, S  (2016-06-16)
Reviewed
Falnes, PØ  (2016-10-10)
Created
Jupe, S  (2016-07-22)
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