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MLLT1 [nucleoplasm]
Stable Identifier
R-HSA-8932918
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Protein ENL, ENL_HUMAN
Locations in the PathwayBrowser for interactor UniProt:P04608%20tat
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
RNA Polymerase II Pre-transcription Events (Homo sapiens)
Elongating transcript encounters a lesion in the template (Homo sapiens)
MLLT1 [nucleoplasm] (Homo sapiens)
RNA Polymerase II Transcription Elongation (Homo sapiens)
Formation of RNA Pol II elongation complex (Homo sapiens)
Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex (Homo sapiens)
MLLT1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q03111 MLLT1
Gene Names
MLLT1, ENL, LTG19, YEATS1
Chain
chain:1-559
Reference Genes
BioGPS Gene:4298 MLLT1
COSMIC (genes):MLLT1 MLLT1
CTD Gene:4298 MLLT1
dbSNP Gene:4298 MLLT1
ENSEMBL:ENSG00000130382 MLLT1
ENSEMBL_homo_sapiens_GENE:ENSG00000130382.9 MLLT1
HGNC:7134 MLLT1
KEGG Gene (Homo sapiens):4298 MLLT1
Monarch:4298 MLLT1
NCBI Gene:4298 MLLT1
OMIM:159556 MLLT1
UCSC:Q03111 MLLT1
Reference Transcript
RefSeq:NM_005934.3 MLLT1
Other Identifiers
11725398_at
11725399_s_at
11763620_a_at
11763626_a_at
16867635
214477_PM_at
214477_at
224993_PM_at
224993_at
32400_at
3847704
3847705
3847706
3847707
3847708
3847709
3847710
3847711
3847712
3847713
3847714
3847715
3847716
3847718
3847721
3847724
3847725
3847726
3847727
3847732
3847735
3847747
3847750
3847753
4298
55750_at
58879_at
8033118
A_23_P153827
A_24_P151295
A_24_P418126
A_33_P3282394
A_33_P3289541
GE63359
GE722971
GO:0001650
GO:0003682
GO:0005515
GO:0005634
GO:0005654
GO:0005730
GO:0005829
GO:0006351
GO:0006355
GO:0008023
GO:0042393
GO:0043226
GO:0043229
GO:0045893
GO:0070577
HMNXSV003021201
Hs.10095.0.S1_3p_at
Hs.10095.0.S1_3p_x_at
Hs.234774.0.S1_3p_at
Hs.234774.0.S1_3p_x_at
ILMN_1706590
PH_hs_0001041
PH_hs_0030983
TC19001091.hg
Participates
as an output of
Elongating transcript encounters a lesion in the template (Homo sapiens)
as a component of
Aborted elongation complex after arrest [nucleoplasm] (Homo sapiens)
Paused processive elongation complex [nucleoplasm] (Homo sapiens)
Arrested processive elongation complex [nucleoplasm] (Homo sapiens)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Homo sapiens)
Elongation complex prior to separation [nucleoplasm] (Homo sapiens)
Processive elongation complex [nucleoplasm] (Homo sapiens)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Homo sapiens)
as an input of
Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex (Homo sapiens)
Inferred To
MLLT1 [nucleoplasm]
(Bos taurus)
MLLT1 [nucleoplasm]
(Canis familiaris)
MLLT1 [nucleoplasm]
(Gallus gallus)
MLLT1 [nucleoplasm]
(Sus scrofa)
mllt1 [nucleoplasm]
(Xenopus tropicalis)
Ghost homologue of MLLT1 [nucleoplasm]
(Caenorhabditis elegans)
Ghost homologue of MLLT1 [nucleoplasm]
(Dictyostelium discoideum)
Ghost homologue of MLLT1 [nucleoplasm]
(Drosophila melanogaster)
Ghost homologue of MLLT1 [nucleoplasm]
(Saccharomyces cerevisiae)
Ghost homologue of MLLT1 [nucleoplasm]
(Schizosaccharomyces pombe)
Mllt1 [nucleoplasm]
(Mus musculus)
Mllt1 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_005925.2
Guide to Pharmacology - Targets
3183
OpenTargets
ENSG00000130382
GeneCards
Q03111
HPA
ENSG00000130382-MLLT1
Ensembl
ENSG00000130382
,
ENST00000252674
,
ENSP00000252674
PRO
Q03111
Pharos - Targets
Q03111
PDB
6HQ0
,
7X8G
,
5J9S
,
6T1I
,
6T1O
,
6HPW
,
6HPX
,
7X88
,
6T1J
,
6HPY
,
7E74
,
7B10
,
7X8B
,
7X8F
,
6T1N
,
7E7C
,
7B0T
,
6T1L
,
6HT0
,
7E7A
,
6HPZ
,
6HT1
,
6T1M
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P50750 CDK9
1
CDK9 [nucleoplasm]
(R-HSA-51801)
0.725
5
UniProt:Q9UHB7 AFF4
1
AFF4 [nucleoplasm]
(R-HSA-8932788)
0.691
8
UniProt:Q8TEK3 DOT1L
1
DOT1L [nucleoplasm]
(R-HSA-3239030)
0.677
8
UniProt:O95070 YIF1A
1
YIF1A [endoplasmic reticulum membrane]
(R-HSA-535599)
0.556
3
UniProt:O00472 ELL2
1
ELL2 [nucleoplasm]
(R-HSA-6807506)
0.527
2
UniProt:P42568 MLLT3
1
MLLT3 [nucleoplasm]
(R-HSA-8932789)
0.527
2
UniProt:P51825 AFF1
0.462
6
UniProt:P04608 tat
1
Tat (P04608) [nucleoplasm]
(R-HIV-175856)
0.462
2
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