AHRR binds ARNT

Stable Identifier
R-HSA-8936851
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The aryl hydrocarbon receptor repressor (AHRR) is predominantly localised in the nucleus of cells (Kanno et al. 2007) and can bind AHR nuclear translocator (ARNT). The resultant AHRR:ARNT complex can compete with AHR:ARNT for binding to the xenobiotic response element (XRE) on target genes such CYP1A1 (Evans et al. 2008, Hahn et al. 2009).

Participants
Participant Of
Orthologous Events