miR-27a binds RUNX1 mRNA

Stable Identifier
R-HSA-8937134
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

MicroRNA miR-27a binds the 3'UTR of the RUNX1 mRNA. As miR-27a inhibits translation of the RUNX1 mRNA without affecting the RUNX1 mRNA stability, miR-27a is assumed to function within the nonendonucleolytic RISC (Ben-Ami et al. 2009).

Literature References
PubMed ID Title Journal Year
19114653 A regulatory interplay between miR-27a and Runx1 during megakaryopoiesis

Ben-Ami, O, Pencovich, N, Lotem, J, Levanon, D, Groner, Y

Proc. Natl. Acad. Sci. U.S.A. 2009
Participants
Participant Of
Authored
Reviewed
Created