Reactome | AHR:TCDD binds ARNT

AHR:TCDD binds ARNT

Stable Identifier

R-HSA-8937177

Type

Reaction

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

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Summation

Ligand-bound aryl hydrocarbon receptor (AHR:TCDD) disassociates from the chaperone subunits to then dimerise with the aryl hydrocarbon receptor nuclear translocator (ARNT) (Lees & Whitelaw 1999).

Literature References

PubMed ID	Title	Journal	Year
10409767	Multiple roles of ligand in transforming the dioxin receptor to an active basic helix-loop-helix/PAS transcription factor complex with the nuclear protein Arnt Lees, MJ, Whitelaw, ML	Mol. Cell. Biol.	1999

Participants

Input

Output

AHR:TCDD:ARNT [nucleoplasm] (Homo sapiens)

Participant Of

hasEvent

Aryl hydrocarbon receptor signalling

Orthologous Events

AHR:TCDD binds ARNT (Bos taurus)

AHR:TCDD binds ARNT (Caenorhabditis elegans)

AHR:TCDD binds ARNT (Canis familiaris)

AHR:TCDD binds ARNT (Danio rerio)

AHR:TCDD binds ARNT (Drosophila melanogaster)

AHR:TCDD binds ARNT (Gallus gallus)

AHR:TCDD binds ARNT (Mus musculus)

AHR:TCDD binds ARNT (Rattus norvegicus)

AHR:TCDD binds ARNT (Sus scrofa)

AHR:TCDD binds ARNT (Taeniopygia guttata)

AHR:TCDD binds ARNT (Xenopus tropicalis)

Authored

Jassal, B (2016-08-30)

Reviewed

D'Eustachio, P (2016-10-11)