PTPN11 binds p-7Y-RUNX1

Stable Identifier
R-HSA-8937744
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Based on mouse studies, tyrosine phosphorylated RUNX1 forms a complex with PTPN11 (SHP2) protein tyrosine phosphatase in the nucleus (Huang et al. 2012).

Literature References
PubMed ID Title Journal Year
22759635 A Src family kinase-Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation

Huang, H, Woo, AJ, Waldon, Z, Schindler, Y, Moran, TB, Zhu, HH, Feng, GS, Steen, H, Cantor, AB

Genes Dev. 2012
Participants
Participant Of
Orthologous Events
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Created