RUNX2 binds tyrosine phosphorylated YAP1

Stable Identifier
R-HSA-8937864
Type
Reaction
Species
Homo sapiens
Compartment
nucleoplasm
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RUNX2 binds tyrosine phosphorylated YAP1
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Based on studies in rat, RUNX2, presumably associated with CBFB, binds YAP1, phosphorylated on an unknown tyrosine residue by SRC and/or YES1. The interaction involves the PY motif of RUNX2 (Zaidi et al. 2004).

Literature References
PubMed ID Title Journal Year
14765127 Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription

Zaidi, SK, Sullivan, AJ, Medina, R, Ito, Y, van Wijnen, AJ, Stein, JL, Lian, JB, Stein, GS

EMBO J. 2004
Participants
Input
Output
Participant Of
hasEvent
Inferred From
Runx2 binds p-Y-Yap1 (Rattus norvegicus)
Authored
Orlic-Milacic, M  (2016-09-07)
Reviewed
Ducy, P  (2017-08-04)
Created
Orlic-Milacic, M  (2016-09-07)