Reactome | NR4A3 [nucleoplasm]

NR4A3 [nucleoplasm]

Stable Identifier

R-HSA-8938004

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Nuclear receptor subfamily 4 group A member 3, NR4A3_HUMAN, CHN, CSMF, MINOR, NOR1, TEC, Nuclear hormone receptor NOR-1, Neuron-derived orphan receptor 1, Mitogen-induced nuclear orphan receptor

Locations in the PathwayBrowser

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Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional regulation by RUNX1 (Homo sapiens)
      - RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Homo sapiens)
        
        NR4A3 gene expression is stimulated by RUNX1:CBFB (Homo sapiens)
        
        NR4A3 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q92570 NR4A3

Gene Names

NR4A3, CHN, CSMF, MINOR, NOR1, TEC

Chain

chain:1-626

Reference Genes

COSMIC (genes):NR4A3 NR4A3

COSMIC (genes):TEC NR4A3

dbSNP Gene:8013 NR4A3

ENSEMBL:ENSG00000119508 NR4A3

Participates

as an output of

NR4A3 gene expression is stimulated by RUNX1:CBFB (Homo sapiens)

Interactors (39)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q3LI67 KRTAP6-3	1	KRTAP6-3 [cytosol] (R-HSA-6810281)	0.556	3
UniProt:Q9H4F8-2 SMOC1			0.556	3
UniProt:Q05086-3 UBE3A			0.556	3
UniProt:P26371 KRTAP5-9	1	KRTAP5-9 [cytosol] (R-HSA-6810265)	0.556	3
UniProt:Q5TA82 LCE2D	1	LCE2D [cytosol] (R-HSA-6814300)	0.556	3
UniProt:Q5T749 KPRP	1	KPRP [cytosol] (R-HSA-9839614)	0.556	3
UniProt:Q6EMK4 VASN			0.556	3
UniProt:Q6P9E2 Q6P9E2			0.556	3
UniProt:Q9BYR3 KRTAP4-4	1	KRTAP4-4 [cytosol] (R-HSA-6809966)	0.556	3
UniProt:Q08AG9 Q08AG9			0.556	3
UniProt:Q12805 EFEMP1	1	EFEMP1 [extracellular region] (R-HSA-2161393)	0.556	3
UniProt:Q92824-2 PCSK5			0.556	3
UniProt:O14633 LCE2B	1	LCE2B [cytosol] (R-HSA-6814295)	0.556	3
UniProt:Q9BYR5 KRTAP4-2	1	KRTAP4-2 [cytosol] (R-HSA-6809948)	0.556	3
UniProt:Q92692-2 NECTIN2			0.556	3
UniProt:Q9Y3S2 ZN330			0.556	3
UniProt:P60328 KRTAP12-3	1	KRTAP12-3 [cytosol] (R-HSA-6810284)	0.556	3
UniProt:P60329 KRTAP12-4	1	KRTAP12-4 [cytosol] (R-HSA-6810278)	0.556	3
UniProt:Q9H2X0 CHRD			0.556	3
UniProt:O14817 TSN4			0.556	3
UniProt:P05187 ALPP	1	ALPP [transport vesicle] (R-HSA-8847823)	0.556	3
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.556	3
UniProt:Q6L8G9 KRTAP5-6	1	KRTAP5-6 [cytosol] (R-HSA-6810276)	0.556	3
UniProt:B2RUY7 VWC2L			0.556	3
UniProt:Q6L8G4 KRTAP5-11	1	KRTAP5-11 [cytosol] (R-HSA-6810303)	0.556	3
UniProt:P60370 KRTAP10-5	1	KRTAP10-5 [cytosol] (R-HSA-6810260)	0.556	5
IntAct:EBI-16436789 CCSB ORF ID			0.556	3
UniProt:Q6L8H2 KRTAP5-3	1	KRTAP5-3 [cytosol] (R-HSA-6810259)	0.556	3
UniProt:Q13526 PIN1	2	PIN1 [nucleoplasm] (R-HSA-936016) PIN1 [cytosol] (R-HSA-9626823)	0.556	3
UniProt:Q9BYQ0 KRTAP9-8	1	KRTAP9-8 [cytosol] (R-HSA-6809953)	0.556	3
UniProt:Q6UY14-3 ADAMTSL4			0.556	3
UniProt:Q9BYQ6 KRTAP4-11	1	KRTAP4-11 [cytosol] (R-HSA-6809960)	0.556	3
UniProt:Q8N5G2 MACO1	1	MACO1 [endoplasmic reticulum membrane] (R-HSA-9714351)	0.556	3
UniProt:Q9BYQ3 KRTAP9-3	1	KRTAP9-3 [cytosol] (R-HSA-6809954)	0.556	3
UniProt:Q9BYQ4 KRTAP9-2	1	KRTAP9-2 [cytosol] (R-HSA-6809965)	0.556	3
UniProt:A8MQ03 CRTP1			0.556	3
UniProt:P55273 CDKN2D	1	CDKN2D [cytosol] (R-HSA-182580)	0.556	3
UniProt:Q9H2F3 HSD3B7	1	HSD3B7 [endoplasmic reticulum membrane] (R-HSA-193441)	0.556	3
UniProt:O95343 SIX3			0.508	3

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