RNF152 binds RRAGA:GDP and Ubiquitin:UBE2D3

Stable Identifier
R-HSA-8938829
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

The ubiquitin E3 ligase RNF152 located in the lysosomal membrane (Zhang et al. 2010) binds GDP-bound RRAGA and the E2-ubiquitin conjugate UBE2N:Ubiquitin prior to ubiquitinating RRAGA (Deng et al. 2015), RNF152, like many E3 ligases, can also autoubiquitinate (Zhang et al. 2010).

Participants
Participant Of
Orthologous Events