PML binds RUNX1

Stable Identifier
R-HSA-8938887
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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RUNX1 interacts with PML, and the interaction involves the C-terminus of PML and the C-terminus of RUNX1. PML targets RUNX1 to nuclear bodies, which may be important for activation of some RUNX1 target genes, such as CSF2 (GM-CSF) (Nguyen et al. 2005).

Literature References
PubMed ID Title Journal Year
15331439 Physical and functional link of the leukemia-associated factors AML1 and PML

Nguyen, LA, Pandolfi, PP, Aikawa, Y, Tagata, Y, Ohki, M, Kitabayashi, I

Blood 2005
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created