RUNX1 binds PAX5 (BSAP)

Stable Identifier
R-HSA-8938951
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The RUNX1:CBFB complex binds to PAX5, also known as BSAP (B-cell specific activating protein). The interaction involves the runt domain of RUNX1 and the paired DNA-binding domain of PAX5 (Libermann et al. 1999).

Literature References
PubMed ID Title Journal Year
10455134 AML1 (CBFalpha2) cooperates with B cell-specific activating protein (BSAP/PAX5) in activation of the B cell-specific BLK gene promoter

Libermann, TA, Pan, Z, Akbarali, Y, Hetherington, CJ, Boltax, J, Yergeau, DA, Zhang, DE

J. Biol. Chem. 1999
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