PRKCB gene expression is stimulated by RUNX1

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R-HSA-8939066
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Reaction [omitted]
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Homo sapiens
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Binding of the RUNX1:CBFB complex to the promoter of the PRKCB gene, encoding Protein kinase C-beta, stimulates PRKCB transcription. RUNX1-mediated upregulation of PRKCB expression may contribute to apoptosis of myeloid cells (Hug et al. 2004).

Literature References
PubMed ID Title Journal Year
14561740 A chromatin immunoprecipitation screen reveals protein kinase Cbeta as a direct RUNX1 target gene

Hug, BA, Ahmed, N, Robbins, JA, Lazar, MA

J. Biol. Chem. 2004
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