Activated ESR1 binds the RUNX2 gene promoter

Stable Identifier
R-HSA-8939904
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Activated ESR1 binds the RUNX2 gene promoter
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Activated estrogen receptor alpha (ESR1) binds estrogen response elements in the proximal P2 promoter of the RUNX2 gene (Kammerer et al. 2013).
Literature References
PubMed ID Title Journal Year
23403054 Estrogen Receptor α (ERα) and Estrogen Related Receptor α (ERRα) are both transcriptional regulators of the Runx2-I isoform

Gutzwiller, S, Kammerer, M, Fournier, B, Stauffer, D, Delhon, I, Seltenmeyer, Y

Mol. Cell. Endocrinol. 2013
Participants
Input
Output
Participates
as an event of
Authored
Orlic-Milacic, M  (2016-09-21)
Reviewed
Ducy, P  (2017-08-04)
Created
Orlic-Milacic, M  (2016-09-21)
Cite Us!