Expression of PERM1

Stable Identifier
R-HSA-8940309
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
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Summation

As inferred from the mouse homolog, the PERM1 gene is transcribed to yield mRNA, the mRNA is translated to yield protein. The PERM1 gene is expressed selectively in muscle where it is activated by PPARGC1A via the estrogen receptor ESRRA, which binds regulatory regions of the PERM1 gene. PERM1 selectively regulates mitochondrial biogenesis and oxidative function.

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