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GH1 [endosome lumen]
Stable Identifier
R-HSA-8942972
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome lumen
Synonyms
Growth Hormone, Somatotropin, SOMA_HUMAN, Growth hormone 1
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Prolactin receptor signaling (Homo sapiens)
Prolactin receptor is internalized (Homo sapiens)
PRLR ligands:p-S349- PRLR:JAK2 dimer [endosome lumen] (Homo sapiens)
Prolactin receptor ligands [endosome lumen] (Homo sapiens)
Growth Hormone [endosome lumen] (Homo sapiens)
GH1 [endosome lumen] (Homo sapiens)
General
Growth hormone is typically used to refer to the endogenous hormone - somatotropin is reserved for synthetic hormone produced by recombinant technology.
External Reference Information
External Reference
UniProt:P01241 GH1
Gene Names
GH1
Chain
signal peptide:1-26, chain:27-217
Reference Genes
BioGPS Gene:2688 GH1
COSMIC (genes):GH1 GH1
CTD Gene:2688 GH1
dbSNP Gene:2688 GH1
ENSEMBL:ENSG00000259384 GH1
ENSEMBL_homo_sapiens_GENE:ENSG00000259384.7 GH1
HGNC:4261 GH1
KEGG Gene (Homo sapiens):2688 GH1
Monarch:2688 GH1
NCBI Gene:2688 GH1
OMIM:139250 GH1
UCSC:P01241 GH1
Reference Transcript
RefSeq:NM_022559.3 GH1
RefSeq:NM_022560.3 GH1
RefSeq:NM_000515.4 GH1
Other Identifiers
11715337_s_at
11715987_a_at
11726973_x_at
1332_f_at
16847711
205840_3p_x_at
205840_PM_x_at
205840_x_at
206885_3p_x_at
206885_PM_x_at
206885_x_at
206886_3p_x_at
206886_PM_x_at
206886_x_at
208068_3p_x_at
208068_PM_x_at
208068_x_at
208069_3p_x_at
208069_PM_x_at
208069_x_at
211151_3p_x_at
211151_PM_x_at
211151_x_at
2688
3766466
3766469
3766473
3766478
3766479
3766487
3766496
3766513
3766514
3766515
3766516
3766517
3766518
3766519
3766520
3766522
3766523
3766525
3766526
3766528
8017505
8180304
A_23_P207194
GE906903
GO:0005125
GO:0005131
GO:0005148
GO:0005179
GO:0005515
GO:0005576
GO:0005615
GO:0005768
GO:0007165
GO:0007259
GO:0008083
GO:0010536
GO:0010828
GO:0019221
GO:0023052
GO:0030312
GO:0031012
GO:0031410
GO:0031667
GO:0031904
GO:0031982
GO:0032355
GO:0036211
GO:0040018
GO:0042531
GO:0043226
GO:0043406
GO:0043568
GO:0045927
GO:0046427
GO:0046872
GO:0048018
GO:0048513
GO:0048856
GO:0051897
GO:0055085
GO:0060396
GO:0062023
GO:0070195
GO:0070977
GO:0098772
HMNXSV003046399
ILMN_2328874
J00148_cds2_f_at
TC17002854.hg
g12408683_3p_s_at
g12408684_3p_s_at
g12408686_3p_s_at
g12408688_3p_s_at
g12408690_3p_s_at
g12408691_3p_s_at
g12408693_3p_s_at
g12408695_3p_s_at
g12545371_3p_s_at
g12545373_3p_s_at
g12545375_3p_s_at
g12545377_3p_s_at
g12545380_3p_s_at
g13027811_3p_s_at
g13027811_3p_x_at
g13027813_3p_s_at
g13027813_3p_x_at
g13027815_3p_s_at
g13027815_3p_x_at
g13027817_3p_s_at
g13027817_3p_x_at
g13027819_3p_s_at
g13543525_3p_s_at
g2459881_3p_s_at
g9963798_3p_s_at
g9963798_3p_x_at
Participates
as a member of
Growth Hormone [endosome lumen] (Homo sapiens)
Other forms of this molecule
GH1 [extracellular region]
Inferred To
CSH1 [endosome lumen]
(Canis familiaris)
CSH1 [endosome lumen]
(Gallus gallus)
CSH1 [endosome lumen]
(Mus musculus)
CSH1 [endosome lumen]
(Rattus norvegicus)
CSH1 [endosome lumen]
(Sus scrofa)
Homologues of CSH1 [endosome lumen]
(Sus scrofa)
Cross References
RefSeq
NP_072053.1
,
NP_000506.2
,
NP_072054.1
OpenTargets
ENSG00000259384
HPA
ENSG00000259384-GH1
GeneCards
P01241
Ensembl
ENST00000323322
,
ENSG00000259384
,
ENST00000351388
,
ENSP00000408486
,
ENST00000458650
,
ENSP00000343791
,
ENSP00000312673
PRO
P01241
Pharos - Targets
P01241
Orphanet
16121
PDB
3HHR
,
1HUW
,
6QIO
,
1HWG
,
1A22
,
1HGU
,
1BP3
,
1AXI
,
1HWH
,
1KF9
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P10912 GHR
7
p-Y332,Y487,Y627-GHR(19-638) [plasma membrane]
(R-HSA-1169226)
GHR(257-638) [plasma membrane]
(R-HSA-1168803)
p-5Y-GHR(19-638) [plasma membrane]
(R-HSA-1168904)
GHR(19-638) [endosome lumen]
(R-HSA-1169263)
GHR(19-256) [extracellular region]
(R-HSA-1168821)
GHR(19-638) [plasma membrane]
(R-HSA-982779)
GHR activated [plasma membrane]
(R-HSA-1168385)
0.73
4
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