p-Y701-STAT1 and p-Y705-STAT3 dissociate from IL27:IL27 receptor

Stable Identifier
R-HSA-8950441
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Signal transducer and activator of transcription 1-alpha/beta (STAT1) and Signal transducer and activator of transcription 3 (STAT3) dissociate from the receptor complex after activation.
This is a BlackBox event since the exact mechanism of this dissociation is unknown.
Literature References
PubMed ID Title Journal Year
18389480 IL-12, IL-23, and IL-27 enhance human beta-defensin-2 production in human keratinocytes

Kanda, N, Watanabe, S

Eur. J. Immunol. 2008
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