Release of mature NEDD8

Stable Identifier
R-HSA-8951644
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

After C-terminal processing by UCHL3 or SENP8, mature NEDD8 is released (Wada et al, 1998; Wu et al, 2003).

Literature References
PubMed ID Title Journal Year
12759363 DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1

Wu, K, Yamoah, K, Dolios, G, Gan-Erdene, T, Tan, P, Chen, A, Lee, CG, Wei, N, Wilkinson, KD, Wang, R, Pan, ZQ

J. Biol. Chem. 2003
9790970 Cleavage of the C-terminus of NEDD8 by UCH-L3

Wada, H, Kito, K, Caskey, LS, Yeh, ET, Kamitani, T

Biochem. Biophys. Res. Commun. 1998
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