RUNX1 gene expression is inhibited by RUNX3

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R-HSA-8951926
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Reaction [omitted]
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Homo sapiens
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Transcription of the RUNX1 gene is repressed by binding of RUNX3 to Runx response elements in the distal (P1) promoter of RUNX1. Expression of RUNX3 is therefore mutually exclusive with expression of RUNX1 in human B cells (Spender et al. 2005).

Literature References
PubMed ID Title Journal Year
15688019 Transcriptional cross-regulation of RUNX1 by RUNX3 in human B cells

Spender, LC, Whiteman, HJ, Karstegl, CE, Farrell, PJ

Oncogene 2005
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