Acetylated RUNX3 binds to BRD2

Stable Identifier
R-HSA-8951977
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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RUNX3 acetylated on lysine residues K94 and K171 binds to BRD2 (bromodomain-containing protein 2). Formation of the RUNX3 complex with BRD2 is stimulated by activated KRAS (Lee et al. 2013).

Literature References
PubMed ID Title Journal Year
24229708 Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma

Lee, YS, Lee, JW, Jang, JW, Chi, XZ, Kim, JH, Li, YH, Kim, MK, Kim, DM, Choi, BS, Kim, EG, Chung, JH, Lee, OJ, Lee, YM, Suh, JW, Chuang, LS, Ito, Y, Bae, SC

Cancer Cell 2013
Participants
Participant Of
This event is regulated
Orthologous Events
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Reviewed
Created