Reactome | PLPP6 [plasma membrane]

PLPP6 [plasma membrane]

Stable Identifier

R-HSA-8952144

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Phospholipid phosphatase 6, PLPP6_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q8TBP5 F174A

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External Reference Information

External Reference

UniProt:Q8IY26 PLPP6

Gene Names

PLPP6, PPAPDC2

Chain

chain:1-295

Reference Genes

BioGPS Gene:403313 PLPP6

CTD Gene:403313 PLPP6

dbSNP Gene:403313 PLPP6

ENSEMBL:ENSG00000205808 PLPP6

HGNC:23682 PLPP6

KEGG Gene (Homo sapiens):403313 PLPP6

Monarch:403313 PLPP6

NCBI Gene:403313 PLPP6

OMIM:611666 PLPP6

UCSC:Q8IY26 PLPP6

Reference Transcript

RefSeq:NM_203453.3 PLPP6

Other Identifiers

0001740647

11743337_at

11751580_a_at

17083277

18096

227385_at

3160728

3160729

3160730

3160731

3160733

3160734

403313

44523_at

51170_at

8154151

A_24_P40907

AAH38108

AK074672

AK128369

AL136231

BAG54667

BC038108

CCDS34981

ENSG00000205808

ENSP00000371307

ENST00000381883

ENST00000381883.3

EntrezGene:403313

EntrezGene:PLPP6

GE88289

GO:0003674

GO:0005575

GO:0005623

GO:0005886

GO:0006629

GO:0006695

GO:0008150

GO:0009058

GO:0016020

GO:0016021

GO:0016787

GO:0016791

GO:0042577

GO:0044281

GO:0046839

HGNC:23682

HPA018096

Hs.29669.0.A1_3p_at

ILMN_1802628

IPR000326

IPR036938

MIM:611666

NM_203453

NP_982278

PF01569

PH_hs_0002565

PLPP6

PLPP6-201

SM00014

TC09000030.hg

UPI00000529F4

Inferred To

PLPP6 [plasma membrane] (Bos taurus)

PLPP6 [plasma membrane] (Caenorhabditis elegans)

PLPP6 [plasma membrane] (Canis familiaris)

PLPP6 [plasma membrane] (Danio rerio)

PLPP6 [plasma membrane] (Dictyostelium discoideum)

PLPP6 [plasma membrane] (Drosophila melanogaster)

PLPP6 [plasma membrane] (Gallus gallus)

PLPP6 [plasma membrane] (Mus musculus)

PLPP6 [plasma membrane] (Rattus norvegicus)

PLPP6 [plasma membrane] (Sus scrofa)

PLPP6 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_982278.3

OpenTargets

ENSG00000205808

GeneCards

Q8IY26

PRO

Q8IY26

HMDB Protein

HMDBP07321

Interactors (46)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H2X3 CLC4M			0.488	2
UniProt:Q96HJ5 MS4A3	2	MS4A3 [specific granule membrane] (R-HSA-6799514) MS4A3 [plasma membrane] (R-HSA-6806321)	0.488	2
UniProt:Q96LL3 CP092			0.488	2
UniProt:Q8TBG9 SYNPR			0.488	2
UniProt:Q96KR7 PHAR3			0.488	2
UniProt:Q5T700 LRAD1			0.488	2
UniProt:P11912 CD79A	2	CD79A [plasma membrane] (R-HSA-197154) p-Y188,Y199-CD79A [plasma membrane] (R-HSA-983539)	0.488	2
UniProt:Q96KR6 F210B			0.488	2
UniProt:Q14802-3 FXYD3			0.488	2
UniProt:Q8TBE3 FNDC9			0.488	2
UniProt:O95484 CLDN9	2	CLDN9 [cell junction] (R-HSA-421271) CLDN9 [plasma membrane] (R-HSA-420016)	0.488	2
UniProt:P15941-11 MUC1			0.488	2
UniProt:Q6UX15-2 Q6UX152			0.488	2
UniProt:Q8TBP5 F174A			0.488	2
UniProt:O94778 AQP8	2	AQP8 [mitochondrial inner membrane] (R-HSA-3779402) AQP8 [plasma membrane] (R-HSA-431756)	0.488	2
UniProt:Q13651 IL10RA	3	p-Y496-IL10RA [plasma membrane] (R-HSA-6784793) IL10RA [plasma membrane] (R-HSA-449841) p-Y446-IL10RA [plasma membrane] (R-HSA-6784810)	0.488	2
UniProt:Q13113 PDZ1I			0.488	2
UniProt:Q16623 STX1A	6	STX1A [plasma membrane] (R-HSA-6794231) STX1A [plasma membrane] (R-HSA-449128) STX1A(?-288) [plasma membrane] (R-HSA-5246518) STX1A(1-?) [cytosol] (R-HSA-3065964) STX1A [cytosol] (R-HSA-9609866) STX1A [endoplasmic reticulum membrane] (R-HSA-9609878)	0.488	2
UniProt:P21964 COMT	2	COMT [cytosol] (R-HSA-175974) COMT [plasma membrane] (R-HSA-379386)	0.488	2
UniProt:Q8N4V1 MMGT1	1	MMGT1 [Golgi membrane] (R-HSA-5216137)	0.488	2
UniProt:Q68D85 NCR3LG1	1	NCR3LG1 [plasma membrane] (R-HSA-5683240)	0.488	2
UniProt:Q15125 EBP	1	EBP [endoplasmic reticulum membrane] (R-HSA-195697)	0.488	2
UniProt:Q14627 IL13RA2	1	IL13RA2 [extracellular region] (R-HSA-449666)	0.488	2
UniProt:P16234-2 PDGFRA			0.488	2
UniProt:Q96K19-5 RNF170			0.488	2
UniProt:P15151 PVR	1	PVR [plasma membrane] (R-HSA-420600)	0.488	2
UniProt:Q13520 AQP6	1	AQP6 [transport vesicle membrane] (R-HSA-431741)	0.488	2
UniProt:Q9NS71 GKN1			0.488	2
UniProt:Q5JX71 F209A			0.488	2
UniProt:Q96FX9 Q96FX9			0.488	2
UniProt:Q9BY50 SEC11C	1	SEC11C [endoplasmic reticulum membrane] (R-HSA-265065)	0.488	2
UniProt:Q5T7V8 GORAB			0.488	2
UniProt:Q9BVX2 T106C			0.488	2
UniProt:O95377 GJB5	1	GJB5 [endoplasmic reticulum membrane] (R-HSA-190643)	0.488	2
UniProt:Q7KYR7-4 Q7KYR74			0.488	2
UniProt:Q99942 RNF5	1	RNF5 [endoplasmic reticulum membrane] (R-HSA-975990)	0.488	2
UniProt:Q8TED1 GPX8	1	GPX8 [endoplasmic reticulum lumen] (R-HSA-3341303)	0.488	2
UniProt:Q96BA8 CREB3L1	7	CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.488	2
UniProt:Q8N205-2 SYNE4			0.488	2
IntAct:EBI-11954883 TMIE			0.488	2
UniProt:Q8TBB6 S7A14			0.488	2
UniProt:Q8N6L0 KASH5			0.488	2
UniProt:Q9Y680 FKBP7			0.488	2
UniProt:A0A024R644 A0A024R644			0.488	2
UniProt:Q9UBN6 TNFRSF10D	1	TNFRSF10D [plasma membrane] (R-HSA-5633374)	0.488	2
UniProt:Q8WWF3 SSMM1			0.488	2