Polyubiquitinated RUNX3 translocates to the cytosol

Stable Identifier
R-HSA-8952399
Type
Reaction [omitted]
Species
Homo sapiens
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Polyubiquitination of RUNX3 by MDM2 promotes translocation of RUNX3 from the nucleus to the cytosol (Chi et al. 2009).

Literature References
PubMed ID Title Journal Year
19808967 Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination

Chi, XZ, Kim, J, Lee, YH, Lee, JW, Lee, KS, Wee, H, Kim, WJ, Park, WY, Oh, BC, Stein, GS, Ito, Y, van Wijnen, AJ, Bae, SC

Cancer Res. 2009
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