Reactome | E2F6 [nucleoplasm]

E2F6 [nucleoplasm]

Stable Identifier

R-HSA-8953089

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcription factor E2F6, E2F6_HUMAN, E2F-6

Locations in the PathwayBrowser for interactor UniProt:Q06587 RING1

Expand all

External Reference Information

External Reference

UniProt:O75461 E2F6

Gene Names

E2F6

Chain

chain:1-281

Reference Genes

BioGPS Gene:1876 E2F6

COSMIC (genes):E2F6 E2F6

CTD Gene:1876 E2F6

dbSNP Gene:1876 E2F6

ENSEMBL:ENSG00000169016 E2F6

HGNC:3120 E2F6

KEGG:hsa:1876 E2F6

Monarch:1876 E2F6

NCBI Gene:1876 E2F6

OMIM:602944 E2F6

UCSC:O75461 E2F6

Reference Transcript

Other Identifiers

11729233_a_at

11729234_at

11729235_s_at

11746243_x_at

11753235_s_at

16894539

1876

203957_PM_at

203957_at

2540583

2540584

2540585

2540586

2540587

2540590

2540591

2540592

2540593

2540594

2540595

2540596

2540597

2540598

2540599

2540601

2540602

2540603

35984_at

3936663

3936664

3936665

3936666

3936667

3936668

3938015

3938016

3938017

3938018

3938019

3938020

3953959

3953960

3953961

3953962

3953963

50412_at

8050336

A_23_P170774

A_32_P12610

A_32_P230720

A_32_P27271

A_33_P3416301

GE81093

GO:0000122

GO:0000785

GO:0000977

GO:0000978

GO:0000981

GO:0001227

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005667

GO:0006355

GO:0006357

GO:0043226

GO:0043565

GO:0046983

GO:0071339

GO:0090575

GO:0140110

HMNXSV003021766

HMNXSV003050171

ILMN_1656196

ILMN_2309608

PH_hs_0031768

TC02001579.hg

TC02004051.hg

g12669917_3p_at

Participates

as an input of

as a component of

Other forms of this molecule

p-S12-E2F6 [nucleoplasm]

Inferred To

E2F6 [nucleoplasm] (Bos taurus)

E2F6 [nucleoplasm] (Canis familiaris)

E2F6 [nucleoplasm] (Gallus gallus)

E2F6 [nucleoplasm] (Sus scrofa)

Ghost homologue of E2F6 [nucleoplasm] (Caenorhabditis elegans)

E2F [nucleoplasm] (Dictyostelium discoideum)

e2f6 [nucleoplasm] (Xenopus tropicalis)

E2f1 [nucleoplasm] (Drosophila melanogaster)

E2f6 [nucleoplasm] (Mus musculus)

E2f6 [nucleoplasm] (Rattus norvegicus)

Cross References

ENSEMBL

ENSP00000438864, ENSP00000370936, ENST00000381525, ENSP00000302159, ENST00000307236, ENSP00000446315, ENST00000546212, ENST00000542100

OpenTargets

ENSG00000169016

HPA

ENSG00000169016-E2F6

PRO

O75461

Pharos - Targets

O75461

GlyGen

O75461

Interactors (31)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14186 TFDP1	1	TFDP1 [nucleoplasm] (R-HSA-68652)	0.953	24
UniProt:Q14188 TFDP2	1	TFDP2 [nucleoplasm] (R-HSA-1362225)	0.907	11
UniProt:Q8N488 RYBP	1	RYBP [nucleoplasm] (R-HSA-8937975)	0.738	5
UniProt:Q14188-5 TFDP2			0.735	11
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.725	5
UniProt:Q99496 RNF2	1	RNF2 [nucleoplasm] (R-HSA-389119)	0.725	5
UniProt:P61244 MAX	1	MAX [nucleoplasm] (R-HSA-3006627)	0.708	6
UniProt:Q8N668 COMMD1	2	COMMD1 [nucleoplasm] (R-HSA-8955094) COMMD1 [cytosol] (R-HSA-8955110)	0.643	4
UniProt:Q969R5 L3MBTL2	2	L3MBTL2 [nucleoplasm] (R-HSA-6804477) polySUMO2-K675,K700-L3MBTL2 [nucleoplasm] (R-HSA-6804480)	0.643	6
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.643	4
UniProt:Q9BYE7 PCGF6	1	PCGF6 [nucleoplasm] (R-HSA-8953572)	0.643	5
UniProt:Q9H0A8 COMMD4	2	COMMD4 [nucleoplasm] (R-HSA-8955106) COMMD4 [cytosol] (R-HSA-8955111)	0.643	4
UniProt:Q8IY57 YAF2	1	YAF2 [nucleoplasm] (R-HSA-8937973)	0.643	6
UniProt:Q8IWI9 MGA	1	MGA [nucleoplasm] (R-HSA-8953093)	0.643	4
UniProt:Q9NX08 COMMD8	2	COMMD8 [nucleoplasm] (R-HSA-8955102) COMMD8 [cytosol] (R-HSA-8955107)	0.643	4
UniProt:Q13185 CBX3	1	CBX3 [nucleoplasm] (R-HSA-427386)	0.643	4
UniProt:Q9Y242 TCF19			0.623	3
UniProt:P41229 KDM5C	1	KDM5C [nucleoplasm] (R-HSA-4754186)	0.597	3
UniProt:P60409 KRTAP10-7	1	KRTAP10-7 [cytosol] (R-HSA-6810279)	0.556	3
UniProt:P83916 CBX1	1	CBX1 [nucleoplasm] (R-HSA-9653629)	0.527	3
UniProt:Q08188 TGM3			0.527	2
UniProt:Q7Z4G1 COMMD6	2	COMMD6 [nucleoplasm] (R-HSA-8955097) COMMD6 [cytosol] (R-HSA-8955098)	0.527	3
UniProt:Q9NWX5 ASB6	1	ASB6 [cytosol] (R-HSA-975412)	0.527	2
UniProt:Q8N344 MIER2			0.527	2
UniProt:P17980 PSMC3	5	PSMC3 [cytosol] (R-HSA-68774) PSMC3 [nucleoplasm] (R-HSA-174313) PSMC3 [secretory granule lumen] (R-HSA-6800917) PSMC3 [extracellular region] (R-HSA-6806496) PSMC3 [ficolin-1-rich granule lumen] (R-HSA-6800429)	0.527	2
UniProt:Q92769 HDAC2	2	HDAC2 [nucleoplasm] (R-HSA-205135) monoSUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958)	0.527	2
UniProt:Q9Y2G2 CARD8	1	CARD8 [cytosol] (R-HSA-6805447)	0.527	2
UniProt:Q06587 RING1	1	RING1 [nucleoplasm] (R-HSA-389113)	0.527	3
UniProt:Q8WVV4 POF1B			0.527	2
UniProt:P47929 LGALS7	1	LGALS7 [cytosol] (R-HSA-9861116)	0.527	2
UniProt:Q92569 PIK3R3	2	PIK3R3 [cytosol] (R-HSA-205223) K63polyUb-PIK3R3 [cytosol] (R-HSA-3080574)	0.488	2

Cite Us!