Reactome | PEX12 [peroxisomal membrane]

PEX12 [peroxisomal membrane]

Stable Identifier

R-HSA-8953911

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

peroxisomal membrane

Synonyms

Peroxisome assembly protein 12, PEX12_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O00623 PEX12

Gene Names

PEX12, PAF3

Chain

chain:1-359

Reference Genes

BioGPS Gene:5193 PEX12

COSMIC (genes):PEX12 PEX12

CTD Gene:5193 PEX12

dbSNP Gene:5193 PEX12

ENSEMBL:ENSG00000108733 PEX12

HGNC:8854 PEX12

Monarch:5193 PEX12

NCBI Gene:5193 PEX12

OMIM:601758 PEX12

UCSC:O00623 PEX12

Reference Transcript

RefSeq:NM_000286.2 PEX12

Other Identifiers

11722830_at

16843462

205094_PM_at

205094_at

35157_at

3753691

3753692

3753693

3753694

3753695

3753696

3753697

3753698

3753699

3753700

3753701

3753702

3753704

5193

8014264

A_24_P416411

GE59561

GO:0000209

GO:0003824

GO:0004842

GO:0005215

GO:0005515

GO:0005777

GO:0005778

GO:0005829

GO:0006513

GO:0006515

GO:0006625

GO:0006886

GO:0007031

GO:0008270

GO:0008320

GO:0015031

GO:0016020

GO:0016558

GO:0016562

GO:0016567

GO:0016740

GO:0030163

GO:0034614

GO:0043161

GO:0043226

GO:0044721

GO:0046872

GO:0055085

GO:0098772

GO:0140096

GO:1990429

GO:1990757

HMNXSV003044965

ILMN_1664448

PH_hs_0002280

TC17001374.hg

U91521_at

g4505720_3p_at

Participates

as a member of

Class I Peroxisomal Membrane Proteins [peroxisomal membrane] (Homo sapiens)

as a component of

PEX2:PEX10:PEX12 [peroxisomal membrane] (Homo sapiens)

Other forms of this molecule

PEX12 [cytosol]

Inferred To

PEX12 [peroxisomal membrane] (Bos taurus)

PEX12 [peroxisomal membrane] (Caenorhabditis elegans)

PEX12 [peroxisomal membrane] (Canis familiaris)

PEX12 [peroxisomal membrane] (Dictyostelium discoideum)

PEX12 [peroxisomal membrane] (Drosophila melanogaster)

PEX12 [peroxisomal membrane] (Gallus gallus)

PEX12 [peroxisomal membrane] (Mus musculus)

PEX12 [peroxisomal membrane] (Rattus norvegicus)

PEX12 [peroxisomal membrane] (Saccharomyces cerevisiae)

PEX12 [peroxisomal membrane] (Schizosaccharomyces pombe)

PEX12 [peroxisomal membrane] (Sus scrofa)

pex12 [peroxisomal membrane] (Xenopus tropicalis)

Cross References

ENSEMBL

ENSP00000225873, ENST00000225873

OpenTargets

ENSG00000108733

HPA

ENSG00000108733-PEX12

PRO

O00623

Pharos - Targets

O00623

Orphanet

PEX12

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P50542 PEX5	4	p-PEX5 [peroxisomal membrane] (R-HSA-9665182) Ub-p-PEX5 [peroxisomal membrane] (R-HSA-9665183) PEX5 [peroxisomal membrane] (R-HSA-9665164) PEX5 [cytosol] (R-HSA-9033132)	0.683	4
UniProt:P49638 TTPA	1	TTPA [cytosol] (R-HSA-2980979)	0.556	3
UniProt:Q15848 ADIPOQ	1	ADIPOQ [extracellular region] (R-HSA-1183052)	0.556	3
UniProt:P17152 TMEM11	1	TMEM11 [mitochondrial inner membrane] (R-HSA-8949578)	0.556	3
UniProt:Q8WVV5 BTN2A2	1	BTN2A2 [plasma membrane] (R-HSA-8851047)	0.556	3
UniProt:Q12982 BNIP2	1	BNIP2 [cytosol] (R-HSA-200792)	0.556	3
UniProt:Q7L5A8 FA2H	1	FA2H [endoplasmic reticulum membrane] (R-HSA-5693771)	0.556	3
UniProt:P29033 GJB2	3	GJB2 [endoplasmic reticulum-Golgi intermediate compartment] (R-HSA-190614) GJB2 [endoplasmic reticulum membrane] (R-HSA-1629779) GJB2 [plasma membrane] (R-HSA-53211)	0.556	3
UniProt:P40855 PEX19	1	PEX19 [cytosol] (R-HSA-3009036)	0.527	2

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