RUNX1 binds the SOCS3 gene

Stable Identifier
R-HSA-8955748
Type
Reaction [binding]
Species
Homo sapiens
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Based on studies in mouse keratinocytes, RUNX1, presumably in complex with CBFB, binds the SOCS3 gene (Scheitz et al. 2012). By sequence similarity, at least one Runx binding element is conserved between human and mouse SOCS3 gene loci.

Literature References
PubMed ID Title Journal Year
23034403 Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer

Scheitz, CJ, Lee, TS, McDermitt, DJ, Tumbar, T

EMBO J. 2012
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