Reactome | UBXN7 [cytosol]

UBXN7 [cytosol]

Stable Identifier

R-HSA-8956071

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

UBX domain-containing protein 7, UBXN7_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O94888 WIPF1

Gene Names

WIPF1, UBXN7, KIAA0794, UBXD7

Chain

initiator methionine:, chain:2-489

Reference Genes

BioGPS Gene:26043 WIPF1

COSMIC (genes):WIPF1 WIPF1

CTD Gene:26043 WIPF1

dbSNP Gene:26043 WIPF1

ENSEMBL:ENSG00000163960 WIPF1

ENSEMBL_homo_sapiens_GENE:ENSG00000163960.12 WIPF1

HGNC:29119 WIPF1

KEGG Gene (Homo sapiens):26043 WIPF1

Monarch:26043 WIPF1

NCBI Gene:26043 WIPF1

OMIM:616379 WIPF1

UCSC:O94888 WIPF1

Reference Transcript

RefSeq:NM_015562.1 WIPF1

Other Identifiers

11755885_a_at

11755910_a_at

11756796_a_at

16963338

16963340

212840_PM_at

212840_at

217100_PM_s_at

217100_s_at

26043

2712837

2712838

2712845

2712847

2712849

2712851

2712852

2712853

2712855

2712857

2712859

2712860

2712861

2712862

2712863

2712864

2712865

2712866

2712869

2712870

2712871

2712872

2712875

2712876

2712882

2712884

2712890

41691_at

68851_at

8093110

8093112

A_23_P358221

A_32_P222515

A_33_P3262292

GE53494

GO:0005515

GO:0005634

GO:0005654

GO:0005783

GO:0005829

GO:0030163

GO:0031625

GO:0034098

GO:0043130

GO:0043161

GO:0043226

GO:0061629

HMNXSV003006614

Hs.127287.0.S1_3p_at

Hs.127287.1.S1_3p_a_at

ILMN_1743594

PH_hs_0007300

TC03002158.hg

TC03002159.hg

Participates

as an input of

as a component of

Other forms of this molecule

ub-UBXN7 [cytosol]

Inferred To

ubxn7 [cytosol] (Danio rerio)

Dmel\CG8892 [cytosol] (Drosophila melanogaster)

UBX5 [cytosol] (Saccharomyces cerevisiae)

ubx2 [cytosol] (Schizosaccharomyces pombe)

Ghost homologue of UBXN7 [cytosol] (Caenorhabditis elegans)

Ghost homologue of UBXN7 [cytosol] (Canis familiaris)

Ghost homologue of UBXN7 [cytosol] (Xenopus tropicalis)

ubxd7 [cytosol] (Dictyostelium discoideum)

UBXN7 [cytosol] (Bos taurus)

UBXN7 [cytosol] (Gallus gallus)

UBXN7 [cytosol] (Plasmodium falciparum)

UBXN7 [cytosol] (Sus scrofa)

Ubxn7 [cytosol] (Mus musculus)

AABR07034438.1 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_056377.1

OpenTargets

ENSG00000115935

GeneCards

O94888

HPA

ENSG00000163960-UBXN7

Ensembl

ENSG00000163960, ENST00000296328, ENSP00000296328

PRO

O94888

Pharos - Targets

O94888

PDB

1WJ4, 2DLX, 5X3P, 5X4L, 2DAL

Interactors (32)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P55072 VCP	8	Me3K315-VCP [cytosol] (R-HSA-8932209) VCP [endoplasmic reticulum membrane] (R-HSA-8943105) VCP [nucleoplasm] (R-HSA-5643745) VCP [secretory granule lumen] (R-HSA-6801039) VCP [ficolin-1-rich granule lumen] (R-HSA-6800425) VCP [extracellular region] (R-HSA-6806191) VCP [azurophil granule lumen] (R-HSA-6800438) VCP [cytosol] (R-HSA-1181251)	0.821	19
UniProt:Q13617 CUL2	3	G76-NEDD8-K689-CUL2 [cytosol] (R-HSA-8952511) CUL2 [nucleoplasm] (R-HSA-1234126) CUL2 [cytosol] (R-HSA-416982)	0.708	20
UniProt:Q13618 CUL3	3	G76-NEDD8-K712-CUL3 [cytosol] (R-HSA-8952516) CUL3 [nucleoplasm] (R-HSA-5635033) CUL3 [cytosol] (R-HSA-975979)	0.623	6
UniProt:Q13619 CUL4A	2	CUL4A [nucleoplasm] (R-HSA-976006) G76-NEDD8-K705-CUL4A [nucleoplasm] (R-HSA-8952514)	0.623	7
IntAct:EBI-4399559 UBIQ			0.591	5
UniProt:Q13620 CUL4B	2	CUL4B [nucleoplasm] (R-HSA-975973) G76-NEDD8-K859-CUL4B [nucleoplasm] (R-HSA-8952522)	0.564	3
UniProt:Q13616 CUL1	3	G76-NEDD8-K720-CUL1 [cytosol] (R-HSA-8952519) CUL1 [nucleoplasm] (R-HSA-187551) CUL1 [cytosol] (R-HSA-174230)	0.564	8
UniProt:Q02548 PAX5	1	PAX5 [nucleoplasm] (R-HSA-158583)	0.556	3
UniProt:Q9UHD9 UBQLN2	1	UBQLN2 [cytosol] (R-HSA-8866007)	0.556	3
UniProt:Q8ND25 ZNRF1	1	ZNRF1 [cytosol] (R-HSA-8850903)	0.556	5
UniProt:P26367 PAX6	1	PAX6 [nucleoplasm] (R-HSA-3009044)	0.556	3
UniProt:Q9HCM9-2 TRIM39			0.556	3
UniProt:Q9BZR9 TRIM8	1	TRIM8 [cytosol] (R-HSA-5624332)	0.556	3
UniProt:Q15038 DAZP2			0.556	3
UniProt:Q6UXS0 CL19A			0.556	3
UniProt:Q9UMX0 UBQLN1	1	UBQLN1 [cytosol] (R-HSA-8866006)	0.556	3
UniProt:Q13952-2 NFYC			0.556	3
UniProt:Q04864-2 REL			0.556	3
UniProt:Q9Y4K3 TRAF6	8	K48polyUb-TRAF6 [cytosol] (R-HSA-6783233) PolyUb-TRAF6 [cytosol] (R-HSA-6782845) TRAF6 [endosome membrane] (R-HSA-450272) K63polyUb-TRAF6 [endosome membrane] (R-HSA-450227) TRAF6 [cytosol] (R-HSA-166366) K63polyUb-TRAF6 [cytosol] (R-HSA-2685681) K63polyUb-TRAF6 [plasma membrane] (R-HSA-936980) TRAF6 [plasma membrane] (R-HSA-936955)	0.556	3
UniProt:O43186 CRX			0.556	3
UniProt:A8MQ03 CRTP1			0.556	3
UniProt:Q9BVG3 TRIM62	1	TRIM62 [cytosol] (R-HSA-5624340)	0.556	3
UniProt:P50221 MEOX1			0.556	3
UniProt:Q92567-2 FAM168A			0.556	3
UniProt:Q96MN5 TEAN2			0.527	2
UniProt:Q9H093 NUAK2			0.527	2
UniProt:Q9BQ90 KLHDC3	1	KLHDC3 [cytosol] (R-HSA-535552)	0.527	2
UniProt:Q9NS56 TOPORS	2	monoSUMO1-K560-TOPORS [nucleoplasm] (R-HSA-4551754) TOPORS [nucleoplasm] (R-HSA-2993791)	0.527	2
UniProt:Q8TAT6 NPLOC4	2	NPLOC4 [nucleoplasm] (R-HSA-5654987) NPLOC4 [cytosol] (R-HSA-9755492)	0.499	5
UniProt:Q16665 HIF1A	7	HN-HIF1A [cytosol] (R-HSA-1234110) 2xHP-HIF1A [nucleoplasm] (R-HSA-1234105) 2xHP-HIF1A [cytosol] (R-HSA-1234131) p-Y565,S797-HIF1A [cytosol] (R-HSA-9634700) p-Y565-HIF1A [cytosol] (R-HSA-8857584) HIF1A [cytosol] (R-HSA-1234102) HIF1A [nucleoplasm] (R-HSA-1234135)	0.499	3
UniProt:Q15843 NEDD8	8	C111-AcM-UBE2M-G76-NEDD8 [nucleoplasm] (R-HSA-8952504) NEDD8 [nucleoplasm] (R-HSA-8955926) C116-AcM-UBE2F-G76-NEDD8 [cytosol] (R-HSA-8951739) NEDD8(77-81) [cytosol] (R-HSA-6782654) NEDD8(1-81) [cytosol] (R-HSA-5690794) C237-UBA3-G76-NEDD8 [cytosol] (R-HSA-8951647) NEDD8 [cytosol] (R-HSA-416969) C111-AcM-UBE2M-G76-NEDD8 [cytosol] (R-HSA-4419895)	0.499	2
UniProt:Q9WTX6	3	Cul1 [cytosol] (R-MMU-8952519) Cul1 [nucleoplasm] (R-MMU-187551) Cul1 [cytosol] (R-MMU-174230)	0.499	3

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