Reactome | TF [endoplasmic reticulum lumen]

TF [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-8956763

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

Serotransferrin, TRFE_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P02787 TF

Gene Names

TF, PRO1400

Chain

signal peptide:1-19, chain:20-698

Reference Genes

COSMIC (genes):TF TF

dbSNP Gene:7018 TF

ENSEMBL:ENSG00000091513 TF

Participates

as a member of

FAM20C substrates [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

apoTF [clathrin-coated endocytic vesicle membrane]

TF [secretory granule lumen]

apoTF [extracellular region]

apoTF [endosome membrane]

p-TF [endoplasmic reticulum lumen]

Inferred To

TF [endoplasmic reticulum lumen] (Bos taurus)

TF [endoplasmic reticulum lumen] (Drosophila melanogaster)

TF [endoplasmic reticulum lumen] (Gallus gallus)

TF [endoplasmic reticulum lumen] (Mus musculus)

TF [endoplasmic reticulum lumen] (Rattus norvegicus)

TF [endoplasmic reticulum lumen] (Sus scrofa)

TF [endoplasmic reticulum lumen] (Xenopus tropicalis)

Interactors (36)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P02786 TFRC	5	TFRC(1-760) [endosome membrane] (R-HSA-8961829) TFRC(1-760) [plasma membrane] (R-HSA-917983) TFRC(1-760) [cytoplasmic vesicle membrane] (R-HSA-434196) TFRC(1-760) [Golgi membrane] (R-HSA-434330) TFRC(1-760) [clathrin-coated endocytic vesicle membrane] (R-HSA-8869124)	0.852	7
UniProt:A5K736 A5K736			0.733	9
UniProt:Q9K0U9 TBPA			0.632	4
UniProt:Q09057 TBPB1			0.618	3
UniProt:Q9K0V0 TBPB			0.558	2
UniProt:Q9BXS9-3 SLC26A6			0.556	3
UniProt:Q96KR6 F210B			0.556	3
UniProt:O15173 PGRMC2	4	PGRMC2 [nuclear envelope] (R-HSA-9707674) PGRMC2 [nucleoplasm] (R-HSA-9707859) PGRMC2 [endoplasmic reticulum membrane] (R-HSA-9714349) PGRMC2 [endosome membrane] (R-HSA-9715090)	0.556	3
UniProt:O43315 AQP9	1	AQP9 [plasma membrane] (R-HSA-431761)	0.556	3
UniProt:A8MZ59 LEUTX	1	LEUTX [nucleoplasm] (R-HSA-9817277)	0.556	3
UniProt:O15529 GPR42			0.556	3
UniProt:Q8NBJ4 GOLM1	2	p-GOLM1 [endoplasmic reticulum lumen] (R-HSA-8956938) GOLM1 [endoplasmic reticulum lumen] (R-HSA-8956710)	0.556	3
UniProt:Q9Y282 ERGI3			0.556	3
UniProt:Q8TED1 GPX8	1	GPX8 [endoplasmic reticulum lumen] (R-HSA-3341303)	0.556	3
UniProt:P08034 GJB1	2	GJB1 [endoplasmic reticulum membrane] (R-HSA-190656) GJB1 [endoplasmic reticulum-Golgi intermediate compartment] (R-HSA-190636)	0.556	3
UniProt:Q99523 SORT1	2	SORT1 [Golgi membrane] (R-HSA-434332) SORT1 [cytoplasmic vesicle membrane] (R-HSA-434221)	0.556	3
UniProt:Q4KMG9 TM52B			0.556	3
UniProt:O00501 CLDN5	2	CLDN5 [cell junction] (R-HSA-421264) CLDN5 [plasma membrane] (R-HSA-419991)	0.556	3
UniProt:Q96TC7 RMD3			0.556	3
UniProt:Q7Z7G2 CPLX4			0.556	3
UniProt:Q9GZR5 ELOVL4	1	ELOVL4 [endoplasmic reticulum membrane] (R-HSA-548705)	0.556	3
UniProt:Q8N9I0 SYT2	3	SYT2 [synaptic vesicle membrane] (R-HSA-194786) SYT2 [plasma membrane] (R-HSA-168795) SYT2 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869116)	0.556	3
UniProt:O43278-2 SPINT1			0.556	3
UniProt:Q3KNW5 SLC10A6	1	SLC10A6 [plasma membrane] (R-HSA-433091)	0.556	3
UniProt:Q7Z5P4 HSD17B13	1	HSD17B13 [cytosol] (R-HSA-8862029)	0.556	3
UniProt:P05091 ALDH2	1	ALDH2 [mitochondrial matrix] (R-HSA-71718)	0.527	2
UniProt:Q9BSW7 SYT17			0.527	2
UniProt:Q8N412 STPG2			0.527	2
UniProt:P60033 CD81	1	CD81 [plasma membrane] (R-HSA-197933)	0.527	6
UniProt:P35219 CAH8			0.527	2
UniProt:Q9H788 SH24A			0.527	2
UniProt:Q9H8H2 DDX31			0.527	2
UniProt:O15232 MATN3	3	MATN3 [extracellular region] (R-HSA-2426297) p-MATN3 [endoplasmic reticulum lumen] (R-HSA-8957026) MATN3 [endoplasmic reticulum lumen] (R-HSA-8956719)	0.527	2
UniProt:Q16659 MAPK6	6	p-3S,T MAPK6 [nucleoplasm] (R-HSA-5692665) MAPK6 [nucleoplasm] (R-HSA-5692686) p-S189 MAPK6 [nucleoplasm] (R-HSA-5687015) p-S189 MAPK6 [cytosol] (R-HSA-5687019) MAPK6 [cytosol] (R-HSA-5686979) ub-MAPK6 [cytosol] (R-HSA-5687000)	0.527	2
UniProt:Q9NQZ2 UTP3	1	UTP3 [nucleoplasm] (R-HSA-6790637)	0.527	2
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-ESR1 [cytosol] (R-HSA-9632177) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.462	2

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