VD3 dissociates from GC

Stable Identifier
R-HSA-8963851
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
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VD3 dissociates from GC
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Vitamin D3 (VD3) is transported to the liver bound to a plasma protein called vitamin D binding protein (GC aka DBP) (Verboven et al. 2002). Before uptake by the liver, VD3 must dissociate from GC.
Literature References
PubMed ID Title Journal Year
11799400 A structural basis for the unique binding features of the human vitamin D-binding protein

De Maeyer, M, Bouillon, R, De Ranter, C, Van Baelen, H, Rabijns, A, Verboven, C

Nat Struct Biol 2002
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Orthologous Events
VD3 dissociates from GC (Bos taurus)
VD3 dissociates from GC (Canis familiaris)
VD3 dissociates from GC (Gallus gallus)
VD3 dissociates from GC (Mus musculus)
VD3 dissociates from GC (Rattus norvegicus)
VD3 dissociates from GC (Sus scrofa)
VD3 dissociates from GC (Xenopus tropicalis)
Authored
Jassal, B  (2017-02-13)
Reviewed
D'Eustachio, P  (2017-06-14)
Created
Jassal, B  (2017-02-13)
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