VD3 translocates from ER membrane to extracellular region

Stable Identifier
R-HSA-8963872
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Vitamin D metabolites such as VD3 are lipophilic and must be transported in the circulation bound to plasma proteins. VD3 translocates to the extracellular region where it binds GC, a vitamin D binding protein (Verboven et al. 2002).
Literature References
PubMed ID Title Journal Year
11799400 A structural basis for the unique binding features of the human vitamin D-binding protein

De Maeyer, M, Bouillon, R, De Ranter, C, Van Baelen, H, Rabijns, A, Verboven, C

Nat Struct Biol 2002
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