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p-STAT5B [nucleoplasm]
Stable Identifier
R-HSA-8982834
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-2 family signaling (Homo sapiens)
Interleukin-15 signaling (Homo sapiens)
p-Y-STAT3:p-STAT5 translocates to the nucleus (Homo sapiens)
p-Y-STAT3:p-STAT5A,p-STAT5B [nucleoplasm] (Homo sapiens)
p-STAT5A, p-STAT5B [nucleoplasm] (Homo sapiens)
p-STAT5B [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51692 STAT5B
Gene Names
STAT5B
Chain
chain:1-787
Reference Genes
BioGPS Gene:6777 STAT5B
COSMIC (genes):STAT5B STAT5B
CTD Gene:6777 STAT5B
dbSNP Gene:6777 STAT5B
ENSEMBL:ENSG00000173757 STAT5B
HGNC:11367 STAT5B
KEGG Gene (Homo sapiens):6777 STAT5B
Monarch:6777 STAT5B
NCBI Gene:6777 STAT5B
OMIM:604260 STAT5B
UCSC:P51692 STAT5B
Reference Transcript
RefSeq:NM_012448.3 STAT5B
Other Identifiers
0001660746
11720228_at
11720229_a_at
16845096
205026_at
212549_at
212550_at
33869_at
3721664
3721670
3721671
3721672
3721673
3721680
3721687
3757771
3757772
3757773
3757774
3757775
3757776
3757777
3757778
3757780
3757781
3757782
3757785
3757786
3757787
3757789
3757791
3757793
3757795
3757796
3757798
3757799
3757800
3757801
3757803
3757805
3757807
3757808
3757811
3757812
3757824
472_at
473_g_at
6777
8015590
A_23_P100788
A_33_P3380867
GE56366
GE61443
GO:0000003
GO:0000228
GO:0000278
GO:0000790
GO:0000978
GO:0000981
GO:0001228
GO:0001553
GO:0001779
GO:0002376
GO:0003674
GO:0003677
GO:0003682
GO:0003700
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006355
GO:0006357
GO:0006629
GO:0006790
GO:0006810
GO:0006950
GO:0006952
GO:0007049
GO:0007155
GO:0007165
GO:0007259
GO:0007548
GO:0007565
GO:0007595
GO:0008134
GO:0008150
GO:0008219
GO:0008283
GO:0008284
GO:0009058
GO:0019218
GO:0019221
GO:0019530
GO:0019915
GO:0030154
GO:0030155
GO:0030856
GO:0032355
GO:0032743
GO:0032819
GO:0032825
GO:0032870
GO:0033077
GO:0034641
GO:0035259
GO:0035723
GO:0038110
GO:0038111
GO:0038113
GO:0040007
GO:0040011
GO:0040014
GO:0040018
GO:0042104
GO:0042127
GO:0042448
GO:0042592
GO:0043029
GO:0043066
GO:0043226
GO:0043434
GO:0044281
GO:0045579
GO:0045588
GO:0045621
GO:0045647
GO:0045648
GO:0045931
GO:0045944
GO:0045954
GO:0046543
GO:0046544
GO:0046983
GO:0048541
GO:0048856
GO:0048870
GO:0050729
GO:0060397
GO:0070669
GO:0070670
GO:0070672
GO:0071363
GO:0071364
GO:0097531
Hs.24064.0.A1_3p_at
Hs.24064.0.A2_3p_at
ILMN_1684034
ILMN_1777783
PH_hs_0025369
TC17001529.hg
U47686_s_at
U48730_at
g6912687_3p_at
Participant Of
hasMember
p-STAT5A, p-STAT5B [nucleoplasm]
Other forms of this molecule
p-STAT5B [cytosol]
p-Y699-STAT5B [nucleoplasm]
p-Y699-STAT5B [cytosol]
STAT5B [cytosol]
Inferred To
phospho-Stat5b [nucleoplasm] (Mus musculus)
phospho-Stat5b [nucleoplasm] (Rattus norvegicus)
phospho-Stat92E [nucleoplasm] (Drosophila melanogaster)
phospho-STAT5B [nucleoplasm] (Canis familiaris)
phospho-stat5a [nucleoplasm] (Danio rerio)
phospho-p-STAT5B [nucleoplasm] (Gallus gallus)
phospho-sta-1 [nucleoplasm] (Caenorhabditis elegans)
phospho-dstD [nucleoplasm] (Dictyostelium discoideum)
Modified Residues
Name
O4'-phospho-L-tyrosine at 649
Coordinate
649
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_036580.2
OpenTargets
ENSG00000173757
HPA
ENSG00000173757-STAT5B
ZINC - Substances
STA5B_HUMAN
GeneCards
P51692
Ensembl
ENSG00000173757
,
ENSP00000293328
,
ENST00000293328
ZINC target
P51692
PRO
P51692
ZINC - Predictions - Purchasable
STA5B_HUMAN
Orphanet
15564
PDB
6MBZ
,
6MBW
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P00519 ABL1
5
p-Y226,Y393-ABL1 [nucleoplasm]
(R-HSA-8985251)
ABL1 [cytosol]
(R-HSA-375987)
p-S456-ABL1 [nucleoplasm]
(R-HSA-5686576)
ABL1 [nucleoplasm]
(R-HSA-5686579)
p-Y226,Y393-ABL1 [cytosol]
(R-HSA-8942610)
0.558
2
UniProt:P38936 CDKN1A
5
p-Y77-CDKN1A [cytosol]
(R-HSA-8942601)
p-T145-CDKN1A [cytosol]
(R-HSA-198614)
CDKN1A [cytosol]
(R-HSA-182512)
p-S130-CDKN1A [nucleoplasm]
(R-HSA-187857)
CDKN1A [nucleoplasm]
(R-HSA-182585)
0.556
3
UniProt:Q71SY5 MED25
1
MED25 [nucleoplasm]
(R-HSA-212414)
0.556
3
UniProt:O75604 USP2
2
USP2 [cytosol]
(R-HSA-5212661)
USP2 [nucleoplasm]
(R-HSA-5689946)
0.556
3
UniProt:Q09028 RBBP4
1
RBBP4 [nucleoplasm]
(R-HSA-212223)
0.556
3
UniProt:P19320 VCAM1
1
VCAM1 [plasma membrane]
(R-HSA-197834)
0.527
4
UniProt:Q9UGK3 STAP2
2
STAP2 [cytosol]
(R-HSA-8848028)
p-Y250-STAP2 [plasma membrane]
(R-HSA-8848079)
0.524
10
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