Reactome | GRB2 [cytosol]

GRB2 [cytosol]

Stable Identifier

R-HSA-8983328

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

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Locations in the PathwayBrowser for interactor UniProt:P50570

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External Reference Information

External Reference

UniProt:P62993 GRB2

Gene Names

GRB2, ASH

Chain

chain:1-217

Reference Genes

BioGPS Gene:2885 GRB2

COSMIC (genes):GRB2 GRB2

CTD Gene:2885 GRB2

dbSNP Gene:2885 GRB2

ENSEMBL:ENSG00000177885 GRB2

HGNC:4566 GRB2

KEGG Gene (Homo sapiens):2885 GRB2

Monarch:2885 GRB2

NCBI Gene:2885 GRB2

OMIM:108355 GRB2

UCSC:P62993 GRB2

Reference Transcript

Other Identifiers

0007050215

11718334_a_at

11741435_s_at

1565_s_at

16848807

215075_s_at

223049_at

2885

33855_at

3770746

3770747

3770748

3770749

3770750

3770751

3770752

3770753

3770754

3770755

3770756

3770757

3770758

3770761

3770772

3770773

3770774

3770777

3770778

46217_at

8018364

A_23_P77847

A_24_P39654

A_24_P407717

GE78983

GE83126

GO:0000003

GO:0000165

GO:0000902

GO:0001784

GO:0002376

GO:0003674

GO:0003723

GO:0005154

GO:0005168

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005768

GO:0005794

GO:0005829

GO:0005886

GO:0005911

GO:0006464

GO:0006810

GO:0006950

GO:0007010

GO:0007155

GO:0007165

GO:0007173

GO:0007265

GO:0007411

GO:0007568

GO:0008150

GO:0008180

GO:0008286

GO:0008543

GO:0009790

GO:0012506

GO:0016020

GO:0016032

GO:0016192

GO:0017124

GO:0019221

GO:0019899

GO:0019901

GO:0019903

GO:0019904

GO:0022607

GO:0030154

GO:0030674

GO:0030838

GO:0031295

GO:0031410

GO:0031532

GO:0031623

GO:0032991

GO:0035635

GO:0035723

GO:0038095

GO:0038096

GO:0038128

GO:0040011

GO:0042059

GO:0042770

GO:0042802

GO:0043226

GO:0043408

GO:0043560

GO:0044403

GO:0044877

GO:0046579

GO:0046875

GO:0048011

GO:0048646

GO:0048856

GO:0048870

GO:0050900

GO:0051219

GO:0051897

GO:0060670

GO:0061024

GO:0065003

GO:0070062

GO:0070436

GO:0071479

GO:2000379

HMNXSV003047633

Hs.296381.1.A1_3p_a_at

ILMN_1742521

ILMN_1748797

M96995_s_at

PH_hs_0024870

TC17001877.hg

g12005510_3p_at

Participates

as a component of

as an input of

Inferred To

Grb2 [cytosol] (Mus musculus)

Grb2 [cytosol] (Rattus norvegicus)

GRB2 [cytosol] (Bos taurus)

GRB2 [cytosol] (Canis familiaris)

GRB2 [cytosol] (Gallus gallus)

GRB2 [cytosol] (Sus scrofa)

grb2b [cytosol] (Danio rerio)

Cross References

RefSeq

NP_002077.1, NP_987102.1

OpenTargets

ENSG00000177885

HPA

ENSG00000177885-GRB2

GeneCards

P62993

ZINC - Substances

GRB2_HUMAN

ZINC target

P62993

Ensembl

ENSG00000177885, ENSP00000339007, ENSP00000317360, ENSP00000496913, ENST00000392564, ENSP00000376345, ENST00000392563, ENSP00000376346, ENST00000392562, ENST00000648046, ENSP00000376347, ENST00000316804, ENST00000316615

PRO

P62993

ZINC - Predictions - Purchasable

GRB2_HUMAN

HMDB Protein

HMDBP11487

PDB

1JYQ, 6WM1, 1ZFP, 3IN8, 3WA4, 4P9Z, 1GFC, 6ICH, 6SDF, 3IMD, 1JYR, 3N7Y, 2VWF, 3MXC, 6ICG, 1FYR, 2VVK, 2AOB, 1TZE, 3S8N, 1CJ1, 1QG1, 3N8M, 1FHS, 5CDW, 2H46, 1IO6, 1BMB, 1GHU, 3C7I, 2H5K, 1GRI, 3MXY, 2AOA, 3S8L, 3S8O, 1GCQ, 6VK2, 1X0N, 3IN7, 4P9V, 2W0Z, 1BM2, 3OV1, 3N84, 6WO2, 3KFJ, 1GFD, 1AZE, 3IMJ, 2HUW, 1JYU, 3OVE

Interactors (253)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P00533 EGFR	59	p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR M766_A767insASV [plasma membrane] (R-HSA-1996343) p-6Y-EGFR D770_N771insNPH [plasma membrane] (R-HSA-1996342) p-6Y-EGFR V738_K739insKIPVAI [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541) p-6Y-EGFR A289V [plasma membrane] (R-HSA-1996334) p-6Y-EGFR T263P [plasma membrane] (R-HSA-1996336) p-6Y-EGFR G598V [plasma membrane] (R-HSA-1996339) p-6Y-EGFR R108K [plasma membrane] (R-HSA-1996338) p-6Y-EGFR A289T [plasma membrane] (R-HSA-1996341) p-6Y-EGFR G719C [plasma membrane] (R-HSA-1177530) p-6Y-EGFR A289D [plasma membrane] (R-HSA-1996340) p-6Y-EGFR G719A [plasma membrane] (R-HSA-1177528) EGFR L858R;T790M [plasma membrane] (R-HSA-1181386) EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1181399) EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996322) EGFR V738_K739insKIPVAI [plasma membrane] (R-HSA-1996325) EGFR M766_A767insASV [plasma membrane] (R-HSA-1996326) EGFR D770_N771insNPH [plasma membrane] (R-HSA-1996317) EGFR L858R [plasma membrane] (R-HSA-1173212) EGFR G719S [plasma membrane] (R-HSA-1169418) EGFR E746_A750del [plasma membrane] (R-HSA-1181211) EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228010) EGFR A289V [plasma membrane] (R-HSA-1996321) EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228012) EGFR L747_T751del [plasma membrane] (R-HSA-1228015) EGFR A289D [plasma membrane] (R-HSA-1996327) EGFR L861Q [plasma membrane] (R-HSA-1177542) EGFR R108K [plasma membrane] (R-HSA-1996330) EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228034) EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228031) EGFR G719A [plasma membrane] (R-HSA-1177532) EGFR A289T [plasma membrane] (R-HSA-1996306) EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228025) EGFR G719C [plasma membrane] (R-HSA-1177531) EGFR T263P [plasma membrane] (R-HSA-1996315) EGFR G598V [plasma membrane] (R-HSA-1996314) EGFR L747_S752del [plasma membrane] (R-HSA-1228016) EGFR [endosome membrane] (R-HSA-9611160) p-4Y-EGFR [plasma membrane] (R-HSA-180287) p-Y992,Y1045,Y1068,Y1086,Y1173-EGFR [plasma membrane] (R-HSA-8864019) p-Y1086,Y1101-EGFR [plasma membrane] (R-HSA-179868) EGFR [plasma membrane] (R-HSA-179837) p-6Y-EGFR [plasma membrane] (R-HSA-179803)	0.981	56
UniProt:P29353 SHC1	5	p-Y427-SHC1 [cytosol] (R-HSA-74684) SHC1 [cytosol] (R-HSA-74680) p-Y349,Y350-SHC1 [cytosol] (R-HSA-180276) p-Y-SHC1 [cytosol] (R-HSA-162568) p-Y349,Y350,Y427-SHC1 [cytosol] (R-HSA-912321)	0.974	31
UniProt:Q07889 SOS1	3	SOS1 [plasma membrane] (R-HSA-983559) p-4S-SOS1 [cytosol] (R-HSA-109821) SOS1 [cytosol] (R-HSA-64847)	0.97	27
UniProt:P22681 CBL	39	CBL R420Q [cytosol] (R-HSA-9706186) CBL R420G [cytosol] (R-HSA-9706203) CBL Y371H [cytosol] (R-HSA-9706680) CBL H398Y [cytosol] (R-HSA-9706639) CBL P417A [cytosol] (R-HSA-9706636) CBL S376F [cytosol] (R-HSA-9706643) CBL del366-409 [cytosol] (R-HSA-9706179) CBL del366-477 [cytosol] (R-HSA-9706176) CBL R499L [cytosol] (R-HSA-9706678) CBL L380P [cytosol] (R-HSA-9706630) CBL L287R [cytosol] (R-HSA-9706693) CBL L380R [cytosol] (R-HSA-9706635) CBL G375P [cytosol] (R-HSA-9706219) CBL P417L [cytosol] (R-HSA-9706634) CBL H398Q [cytosol] (R-HSA-9706633) CBL P417R [cytosol] (R-HSA-9706632) CBL R499* [cytosol] (R-HSA-9706670) CBL H398R [cytosol] (R-HSA-9706638) CBL H398P [cytosol] (R-HSA-9706637) CBL G375fs16 [cytosol] (R-HSA-9706211) CBL R420 [cytosol] (R-HSA-9706208) CBL H398D [cytosol] (R-HSA-9706631) CBL Y371C [cytosol] (R-HSA-9706694) CBL G375S [cytosol] (R-HSA-9706214) CBL Y371D [cytosol] (R-HSA-9706687) CBL Y371S [cytosol] (R-HSA-9706674) CBL P417S [cytosol] (R-HSA-9706642) CBL H398N [cytosol] (R-HSA-9706641) CBL R420P [cytosol] (R-HSA-9706193) CBL Y371N [cytosol] (R-HSA-9706679) CBL R499Q [cytosol] (R-HSA-9706677) CBL R420L [cytosol] (R-HSA-9706197) CBL P417H [cytosol] (R-HSA-9706644) p-Y371-CBL [cytosol] (R-HSA-182940) p-Y371-CBL [plasma membrane] (R-HSA-182923) PolyUb,p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-8848826) p-Y700,Y731,Y774-CBL [cytosol] (R-HSA-912656) p-Y-CBL [cytosol] (R-HSA-8875457) CBL [cytosol] (R-HSA-112199)	0.961	18
UniProt:Q13191 CBLB	1	CBLB [cytosol] (R-HSA-976009)	0.96	26
UniProt:Q9UQC2 GAB2	5	p-Y452,Y476,Y584-GAB2 [cytosol] (R-HSA-2685615) p-Y-GAB2 [cytosol] (R-HSA-912529) GAB2 [cytosol] (R-HSA-508239) p-5Y-GAB2 [cytosol] (R-HSA-8855574) p-Y643-GAB2 [cytosol] (R-HSA-9677149)	0.95	15
UniProt:Q07890 SOS2	1	SOS2 [cytosol] (R-HSA-167221)	0.933	11
UniProt:Q9UJM3 ERRFI			0.928	16
UniProt:O00401 WASL	4	p-Y256-WASL [cytosol] (R-HSA-2197672) N-WASP [cytosol] (R-HSA-201873) WASL [plasma membrane] (R-HSA-203010) WASL [endocytic vesicle membrane] (R-HSA-535012)	0.928	11
UniProt:P18433 PTPRA	1	PTPRA [plasma membrane] (R-HSA-388755)	0.921	13
UniProt:P11274 BCR	4	BCR-FGFR1 fusion [cytosol] (R-HSA-1604524) BCR [cytosol] (R-HSA-195200) pY177-BCR-p-FGFR1 fusion [cytosol] (R-HSA-1839041) BCR-p-FGFR1 fusion [cytosol] (R-HSA-1838979)	0.921	11
UniProt:O95630 STAMBP	1	STAMBP [cytosol] (R-HSA-5693063)	0.92	9
UniProt:Q13094 LCP2	2	LCP2 [cytosol] (R-HSA-202306) p-Y113,128,145-LCP2 [cytosol] (R-HSA-202175)	0.918	18
UniProt:P50570 DNM2	5	DNM2 [cytosol] (R-HSA-2213180) DNM2 [Golgi membrane] (R-HSA-2980842) DNM2 [plasma membrane] (R-HSA-2984201) DNM2 [endocytic vesicle membrane] (R-HSA-2029000) DNM2 [lysosomal membrane] (R-HSA-2980840)	0.918	9
UniProt:Q9H706 GARE1			0.905	11
UniProt:Q13480 GAB1	4	p-5Y-GAB1 [cytosol] (R-HSA-180344) GAB1 [cytosol] (R-HSA-179795) p-Y627,Y659-GAB1 [cytosol] (R-HSA-180496) p-Y-GAB1 [cytosol] (R-HSA-8855306)	0.898	12
UniProt:Q9ULH1 ASAP1	1	ASAP1 [cytosol] (R-HSA-5620905)	0.894	10
UniProt:Q06124 PTPN11	4	PTPN11 [nucleoplasm] (R-HSA-8937745) p-Y546-PTPN11 [cytosol] (R-HSA-1369081) p-Y546,Y584-PTPN11 [cytosol] (R-HSA-162573) PTPN11 [cytosol] (R-HSA-162563)	0.893	10
UniProt:P04626 ERBB2	117	ERBB2 G309A [plasma membrane] (R-HSA-9665349) ERBB2 G309E [plasma membrane] (R-HSA-9665342) ERBB2 S310F [plasma membrane] (R-HSA-9665350) ERBB2 S310Y [plasma membrane] (R-HSA-9665344) p-6Y-ERBB2 G309A [plasma membrane] (R-HSA-9665381) p-6Y-ERBB2 G309E [plasma membrane] (R-HSA-9665382) p-6Y-ERBB2 S310F [plasma membrane] (R-HSA-9665379) p-6Y-ERBB2 S310Y [plasma membrane] (R-HSA-9665385) p-Y-ERBB2 L755P [plasma membrane] (R-HSA-9654268) p-Y-ERBB2 I767M [plasma membrane] (R-HSA-9654303) p-Y-ERBB2 A775_G776insYVMA [plasma membrane] (R-HSA-9665656) p-Y-ERBB2 T798I [plasma membrane] (R-HSA-9654618) p-Y-ERBB2 T862A [plasma membrane] (R-HSA-9654695) p-Y-ERBB2 T798M [plasma membrane] (R-HSA-9654615) p-Y-ERBB2 H878Y [plasma membrane] (R-HSA-9654833) p-Y-ERBB2 V777L [plasma membrane] (R-HSA-9654401) p-Y-ERBB2 L755S [plasma membrane] (R-HSA-9654194) p-Y-ERBB2 V777E [plasma membrane] (R-HSA-9654397) p-Y-ERBB2 V777M [plasma membrane] (R-HSA-9654398) p-Y-ERBB2 L755M [plasma membrane] (R-HSA-9654191) p-Y-ERBB2 A771_Y772insYVMA [plasma membrane] (R-HSA-9665652) p-Y-ERBB2 L755W [plasma membrane] (R-HSA-9654193) p-Y-ERBB2 T733I [plasma membrane] (R-HSA-9654610) p-Y-ERBB2 H878R [plasma membrane] (R-HSA-9654835) p-Y-ERBB2 L869R [plasma membrane] (R-HSA-9654730) p-Y-ERBB2 G776S [plasma membrane] (R-HSA-9664608) p-Y-ERBB2 L869Q [plasma membrane] (R-HSA-9654732) p-Y-ERBB2 G776L [plasma membrane] (R-HSA-9664600) p-Y-ERBB2 G776V [plasma membrane] (R-HSA-9664602) p-Y-ERBB2 G776C [plasma membrane] (R-HSA-9664611) ERBB2 D769Y [plasma membrane] (R-HSA-9646620) ERBB2 L755P [plasma membrane] (R-HSA-9646494) ERBB2 V842I [plasma membrane] (R-HSA-9646703) ERBB2 H878Y [plasma membrane] (R-HSA-9646824) ERBB2 T798M [plasma membrane] (R-HSA-9646825) ERBB2 D769H [plasma membrane] (R-HSA-9646617) ERBB2 T862A [plasma membrane] (R-HSA-9649434) ERBB2 A775_G776insYVMA [plasma membrane] (R-HSA-9665621) ERBB2 L755S [plasma membrane] (R-HSA-9646423) ERBB2 I767M [plasma membrane] (R-HSA-9646737) ERBB2 V777L [plasma membrane] (R-HSA-9646579) ERBB2 D769N [plasma membrane] (R-HSA-9646636) ERBB2 T733I [plasma membrane] (R-HSA-9646765) ERBB2 V777M [plasma membrane] (R-HSA-9646591) ERBB2 V777E [plasma membrane] (R-HSA-9646586) ERBB2 L755W [plasma membrane] (R-HSA-9646516) ERBB2 L755M [plasma membrane] (R-HSA-9646517) ERBB2 A771_Y772insYVMA [plasma membrane] (R-HSA-9665622) ERBB2 H878R [plasma membrane] (R-HSA-9646822) ERBB2 V842E [plasma membrane] (R-HSA-9646710) ERBB2 T798I [plasma membrane] (R-HSA-9646823) ERBB2 R896C [plasma membrane] (R-HSA-9646714) ERBB2 P780_Y781insGSP [plasma membrane] (R-HSA-9646667) ERBB2 R896H [plasma membrane] (R-HSA-9646728) ERBB2 G778_P780insGSP [plasma membrane] (R-HSA-9665625) ERBB2 G776S [plasma membrane] (R-HSA-9664463) ERBB2 L869R [plasma membrane] (R-HSA-9646827) ERBB2 L869Q [plasma membrane] (R-HSA-9646828) ERBB2 G776C [plasma membrane] (R-HSA-9664457) ERBB2 G776L [plasma membrane] (R-HSA-9664454) ERBB2 G776V [plasma membrane] (R-HSA-9664450) p-6Y-ERBB2 V777L [plasma membrane] (R-HSA-9647214) p-6Y-ERBB2 H878Y [plasma membrane] (R-HSA-9647215) ERBB2 L755_T759del [plasma membrane] (R-HSA-9663599) p-6Y-ERBB2 R896C [plasma membrane] (R-HSA-9647208) p-6Y-ERBB2 V842I [plasma membrane] (R-HSA-9647209) p-6Y-ERBB2 I767M [plasma membrane] (R-HSA-9647211) p-6Y-ERBB2 T862A [plasma membrane] (R-HSA-9654692) p-6Y-ERBB2 D769H [plasma membrane] (R-HSA-9647200) p-6Y-ERBB2 T798I [plasma membrane] (R-HSA-9647202) p-6Y-ERBB2 L755P [plasma membrane] (R-HSA-9647196) p-6Y-ERBB2 P780_Y781insGSP [plasma membrane] (R-HSA-9647198) p-6Y-ERBB2 L755S [plasma membrane] (R-HSA-9647216) p-6Y-ERBB2 A775_G776insYVMA [plasma membrane] (R-HSA-9665650) p-6Y-ERBB2 T798M [plasma membrane] (R-HSA-9647218) p-6Y-ERBB2 A771_Y772insYVMA [plasma membrane] (R-HSA-9665644) p-6Y-ERBB2 D769Y [plasma membrane] (R-HSA-9647199) p-6Y-ERBB2 V777E [plasma membrane] (R-HSA-9647210) p-6Y-ERBB2 T733I [plasma membrane] (R-HSA-9647195) p-6Y-ERBB2 L755M [plasma membrane] (R-HSA-9647204) p-6Y-ERBB2 V777M [plasma membrane] (R-HSA-9647205) p-6Y-ERBB2 V842E [plasma membrane] (R-HSA-9647206) p-6Y-ERBB2 D769N [plasma membrane] (R-HSA-9647207) p-6Y-ERBB2 R896H [plasma membrane] (R-HSA-9647217) p-6Y-ERBB2 L755W [plasma membrane] (R-HSA-9647201) p-6Y-ERBB2 G778_P780insGSP [plasma membrane] (R-HSA-9665634) p-6Y-ERBB2 H878R [plasma membrane] (R-HSA-9647203) p-6Y-ERBB2 E693K [plasma membrane] (R-HSA-9665871) p-6Y-ERBB2 R677L [plasma membrane] (R-HSA-9665864) p-6Y-ERBB2 Q709L [plasma membrane] (R-HSA-9665865) p-6Y-ERBB2 G660D [plasma membrane] (R-HSA-9665866) p-6Y-ERBB2 G660R [plasma membrane] (R-HSA-9665878) p-6Y-ERBB2 V659K [plasma membrane] (R-HSA-9665863) p-6Y-ERBB2 V659E [plasma membrane] (R-HSA-9665874) ERBB2 R678Q [plasma membrane] (R-HSA-9665756) ERBB2 S653C [plasma membrane] (R-HSA-9665754) ERBB2 R677L [plasma membrane] (R-HSA-9665759) ERBB2 G660R [plasma membrane] (R-HSA-9665768) ERBB2 V659E [plasma membrane] (R-HSA-9665752) ERBB2 G660D [plasma membrane] (R-HSA-9665753) ERBB2 V659K [plasma membrane] (R-HSA-9665769) ERBB2 Q709L [plasma membrane] (R-HSA-9665770) ERBB2 E693K [plasma membrane] (R-HSA-9665761) p-6Y-ERBB2 R678Q [plasma membrane] (R-HSA-9665876) p-6Y-ERBB2 S653C [plasma membrane] (R-HSA-9665875) p-Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 [plasma membrane] (R-HSA-8863841) p-Y877,Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 [plasma membrane] (R-HSA-8863836) p-Y1023,Y1139,Y1221,Y1222-ERBB2 [plasma membrane] (R-HSA-8864084) p-Y877,Y1023,Y1139,Y1221,Y1222-ERBB2 [plasma membrane] (R-HSA-8864090) p-Y877-ERBB2 [plasma membrane] (R-HSA-1810438) ERBB2 [plasma membrane] (R-HSA-372889) p-6Y-ERBB2 [plasma membrane] (R-HSA-1963569) p-6Y,Y1112-ERBB2 [plasma membrane] (R-HSA-8864081) p-Y-ERBB2 [plasma membrane] (R-HSA-1678589) p-Y,Y877-ERBB2 [plasma membrane] (R-HSA-1810446) p-7Y,Y1112-ERBB2 [plasma membrane] (R-HSA-8864079) p-7Y-ERBB2 [plasma membrane] (R-HSA-1248698)	0.873	6
UniProt:Q07666 KHDRBS1	3	p-Y435,Y440,Y443-KHDRBS1 [cytosol] (R-HSA-8848995) p-Y435,Y440,Y443-KHDRBS1 [nucleoplasm] (R-HSA-8848970) KHDRBS1 [nucleoplasm] (R-HSA-8848941)	0.868	8
UniProt:P27986 PIK3R1	15	PIK3R1 K379E [plasma membrane] (R-HSA-8944148) PIK3R1 G376R [plasma membrane] (R-HSA-2399717) PIK3R1 Y463_L466del [plasma membrane] (R-HSA-2399546) PIK3R1 H450_E451del [plasma membrane] (R-HSA-2399545) PIK3R1 R574_T576del [plasma membrane] (R-HSA-2399544) PIK3R1 D560Y [plasma membrane] (R-HSA-2399421) PIK3R1 N564D [plasma membrane] (R-HSA-2399427) PIK3R1 K459del [plasma membrane] (R-HSA-2399554) PIK3R1 N564K [plasma membrane] (R-HSA-2399431) PIK3R1 D560H [plasma membrane] (R-HSA-2399432) PIK3R1 R574I [plasma membrane] (R-HSA-2399536) PIK3R1 R574T [plasma membrane] (R-HSA-2399540) K63polyUb-PIK3R1 [cytosol] (R-HSA-3080572) PIK3R1 [plasma membrane] (R-HSA-198365) PIK3R1 [cytosol] (R-HSA-74789)	0.863	6
UniProt:P61978 HNRNPK	2	HNRNPK [nucleoplasm] (R-HSA-71945) SUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532)	0.848	10
UniProt:Q9UKW4 VAV3	2	p-Y173-VAV3 [cytosol] (R-HSA-442287) VAV3 [cytosol] (R-HSA-430152)	0.848	8
UniProt:Q05193 DNM1	3	DNM1 [cytosol] (R-HSA-2213182) DNM1 [lysosomal membrane] (R-HSA-196150) DNM1 [plasma membrane] (R-HSA-177488)	0.829	7
UniProt:Q9Y4K4 M4K5			0.818	5
UniProt:P35235 Ptpn11	5	Ptpn11 [cytosol] (R-MMU-210002) p-Y546,Y584-Shp2 [cytosol] (R-MMU-443116) Ptpn11 [nucleoplasm] (R-MMU-8937745) phospho-Ptpn11 [cytosol] (R-MMU-162573) Ptpn11 [cytosol] (R-MMU-162563)	0.809	7
UniProt:Q8TF74 WIPF2	1	WIPF2 [cytosol] (R-HSA-2197666)	0.804	6
UniProt:Q9UKT9 IKZF3			0.795	8
UniProt:Q9H3S7 PTPN23	1	PTPN23 [nucleoplasm] (R-HSA-9008924)	0.786	7
UniProt:Q12774 ARHGEF5	1	ARHGEF5 [cytosol] (R-HSA-8873909)	0.768	7
UniProt:Q14185 DOCK1	1	DOCK1 [cytosol] (R-HSA-372654)	0.752	5
UniProt:O43516 WIPF1	1	WIPF1 [cytosol] (R-HSA-201874)	0.745	4
UniProt:O00750 PIK3C2B	1	PIK3C2B [cytosol] (R-HSA-1604619)	0.744	5
UniProt:P10721 KIT	111	KIT T417-D419delinsY [plasma membrane] (R-HSA-9680110) KIT C443Y [plasma membrane] (R-HSA-9680045) KIT S476I [plasma membrane] (R-HSA-9680090) KIT K509I [plasma membrane] (R-HSA-9680177) KIT D419A [plasma membrane] (R-HSA-9680051) KIT D419del [plasma membrane] (R-HSA-9680079) KIT S501_A502dup [plasma membrane] (R-HSA-9680105) KIT D419G [plasma membrane] (R-HSA-9680057) KIT N505_F508dup [plasma membrane] (R-HSA-9680085) KIT C443S [plasma membrane] (R-HSA-9680038) KIT D419N [plasma membrane] (R-HSA-9680071) KIT S476N [plasma membrane] (R-HSA-9680097) KIT D419H [plasma membrane] (R-HSA-9680066) KIT V560_L576del [plasma membrane] (R-HSA-9670336) KIT Y823N [plasma membrane] (R-HSA-9669591) KIT Y823C [plasma membrane] (R-HSA-9669585) p6Y-KIT Y823D [plasma membrane] (R-HSA-9669628) p7Y-KIT D816V [plasma membrane] (R-HSA-9669612) p7Y-KIT K642E [plasma membrane] (R-HSA-9669596) p7Y-KIT N822K [plasma membrane] (R-HSA-9669617) p7Y-KIT N822D [plasma membrane] (R-HSA-9669613) p7Y-KIT N822S [plasma membrane] (R-HSA-9669614) p-7Y KIT V654E [plasma membrane] (R-HSA-9669615) p7Y-KIT N822I [plasma membrane] (R-HSA-9669608) p7Y-KIT D816N [plasma membrane] (R-HSA-9669611) p7Y-KIT A829P [plasma membrane] (R-HSA-9669605) p7Y-KIT D816H [plasma membrane] (R-HSA-9669606) p6Y-KIT Y823C [plasma membrane] (R-HSA-9669607) p7Y-KIT K642Q [plasma membrane] (R-HSA-9669601) p6Y-KIT Y823N [plasma membrane] (R-HSA-9669597) p7Y-KIT D816A [plasma membrane] (R-HSA-9669629) p7Y-KIT N822H [plasma membrane] (R-HSA-9669598) p7Y-KIT D816F [plasma membrane] (R-HSA-9671513) p-7Y KIT V654A [plasma membrane] (R-HSA-9669593) p7Y-KIT N822T [plasma membrane] (R-HSA-9669622) p7Y-KIT D816E [plasma membrane] (R-HSA-9671510) p7Y-KIT D816Y [plasma membrane] (R-HSA-9669623) p7Y-KIT N822Y [plasma membrane] (R-HSA-9669619) p7Y-KIT V559D [plasma membrane] (R-HSA-9669620) p7Y-KIT K550I P551_V555del [plasma membrane] (R-HSA-9669602) p-7Y KIT W557_K558del [plasma membrane] (R-HSA-9670352) p-5Y KIT V560_L576del [plasma membrane] (R-HSA-9670348) p7Y-KIT L576P [plasma membrane] (R-HSA-9669616) p7Y-KIT V559_V560del [plasma membrane] (R-HSA-9669618) p7Y-KIT P551_V555del [plasma membrane] (R-HSA-9669621) p7Y-KIT V560G [plasma membrane] (R-HSA-9669610) p7Y-KIT K550_K558del [plasma membrane] (R-HSA-9669624) p7Y-KIT V560E [plasma membrane] (R-HSA-9669603) p7Y-KIT V560D [plasma membrane] (R-HSA-9669626) p7Y-KIT V559A [plasma membrane] (R-HSA-9669625) p7Y-KIT V559I [plasma membrane] (R-HSA-9669609) p7Y-KIT W557R [plasma membrane] (R-HSA-9669627) p7Y-KIT V559G [plasma membrane] (R-HSA-9669600) p7Y-KIT W557G [plasma membrane] (R-HSA-9669604) p7Y-KIT K509I [plasma membrane] (R-HSA-9680180) p7Y-KIT A502_Y503dup [plasma membrane] (R-HSA-9680120) p7Y-KIT S476I [plasma membrane] (R-HSA-9680156) p7Y-KIT C443Y [plasma membrane] (R-HSA-9680138) p7Y-KIT D419A [plasma membrane] (R-HSA-9680129) p7Y-KIT T417-D419delinsY [plasma membrane] (R-HSA-9680165) p7Y-KIT D419H [plasma membrane] (R-HSA-9680132) p7Y-KIT S501_A502dup [plasma membrane] (R-HSA-9680161) p7Y-KIT D419del [plasma membrane] (R-HSA-9680127) p7Y-KIT N505_F508dup [plasma membrane] (R-HSA-9680159) p7Y-KIT D419N [plasma membrane] (R-HSA-9680134) p7Y-KIT C443S [plasma membrane] (R-HSA-9680137) p7Y-KIT S476N [plasma membrane] (R-HSA-9680158) p7Y-KIT D419G [plasma membrane] (R-HSA-9680130) KIT A829P [plasma membrane] (R-HSA-9669426) KIT N822D [plasma membrane] (R-HSA-9669447) KIT V654E [plasma membrane] (R-HSA-9669576) KIT W557R [plasma membrane] (R-HSA-9669581) KIT W557G [plasma membrane] (R-HSA-9669578) KIT V559A [plasma membrane] (R-HSA-9669547) KIT K550I P551_V555del [plasma membrane] (R-HSA-9669444) KIT L576P [plasma membrane] (R-HSA-9669446) KIT V559_V560del [plasma membrane] (R-HSA-9669561) KIT P551_V555del [plasma membrane] (R-HSA-9669433) KIT V559I [plasma membrane] (R-HSA-9669557) KIT K550_K558del [plasma membrane] (R-HSA-9669461) KIT V559G [plasma membrane] (R-HSA-9669554) KIT V559D [plasma membrane] (R-HSA-9669551) KIT W557_K558del [plasma membrane] (R-HSA-9670343) KIT Y823D [plasma membrane] (R-HSA-9669587) KIT D816V [plasma membrane] (R-HSA-9669452) KIT N822Y [plasma membrane] (R-HSA-9669454) KIT T670I [plasma membrane] (R-HSA-9669545) KIT D820E [plasma membrane] (R-HSA-9669449) KIT V654A [plasma membrane] (R-HSA-9669572) KIT D816H [plasma membrane] (R-HSA-9669445) KIT K642E [plasma membrane] (R-HSA-9669443) KIT V560D [plasma membrane] (R-HSA-9669564) KIT N822H [plasma membrane] (R-HSA-9669437) KIT A502_Y503dup [plasma membrane] (R-HSA-9680030) KIT N822K [plasma membrane] (R-HSA-9669464) KIT D816Y [plasma membrane] (R-HSA-9669435) KIT D820A [plasma membrane] (R-HSA-9669460) KIT N822T [plasma membrane] (R-HSA-9669463) KIT D816F [plasma membrane] (R-HSA-9669457) KIT K642Q [plasma membrane] (R-HSA-9669468) KIT D816E [plasma membrane] (R-HSA-9669436) KIT N822I [plasma membrane] (R-HSA-9669453) KIT V560E [plasma membrane] (R-HSA-9669566) KIT N822S [plasma membrane] (R-HSA-9669466) KIT D816N [plasma membrane] (R-HSA-9669451) KIT D816A [plasma membrane] (R-HSA-9669428) KIT V560G [plasma membrane] (R-HSA-9669569) p-8Y-KIT [plasma membrane] (R-HSA-1472116) p-S741,S746-KIT [plasma membrane] (R-HSA-1433492) KIT [plasma membrane] (R-HSA-197662) p-7Y-KIT [plasma membrane] (R-HSA-205207)	0.743	6
UniProt:Q8WV28 BLNK	2	p-5Y-BLNK [plasma membrane] (R-HSA-983579) BLNK [cytosol] (R-HSA-912750)	0.743	5
UniProt:P42336 PIK3CA	25	PIK3CA H1047R [cytosol] (R-HSA-1500716) PIK3CA H1047L [cytosol] (R-HSA-1500714) PIK3CA M1043I [cytosol] (R-HSA-1500719) PIK3CA M1043T [cytosol] (R-HSA-2395934) PIK3CA M1043V [cytosol] (R-HSA-2395932) PIK3CA H1047Y [cytosol] (R-HSA-1500720) PIK3CA E542K [cytosol] (R-HSA-1500701) PIK3CA Q546K [cytosol] (R-HSA-1500705) PIK3CA E545A [cytosol] (R-HSA-2362355) PIK3CA E545K [cytosol] (R-HSA-1500706) PIK3CA E545Q [cytosol] (R-HSA-2362362) PIK3CA Q546E [cytosol] (R-HSA-2362383) PIK3CA E545V [cytosol] (R-HSA-2362365) PIK3CA E542V [cytosol] (R-HSA-2328074) PIK3CA Q546L [cytosol] (R-HSA-2362375) PIK3CA E545G [cytosol] (R-HSA-1500709) PIK3CA Q546H [cytosol] (R-HSA-2362374) PIK3CA Q546R [cytosol] (R-HSA-2362373) PIK3CA Q546P [cytosol] (R-HSA-1500695) PIK3CA E542Q [cytosol] (R-HSA-2328003) PIK3CA R38H [cytosol] (R-HSA-1500718) PIK3CA R38S [cytosol] (R-HSA-2395947) PIK3CA R38G [cytosol] (R-HSA-2395950) PIK3CA R38C [cytosol] (R-HSA-1500691) PIK3CA [cytosol] (R-HSA-74787)	0.742	5
UniProt:P62993 GRB2	1	GRB2 [cytosol] (R-HSA-8983328)	0.738	5
UniProt:Q6ZUJ8 PIK3AP1	1	p-4Y-PIK3AP1 [plasma membrane] (R-HSA-984814)	0.738	5
UniProt:P35570 Irs1	7	p-Y-Irs1 [cytosol] (R-RNO-112362) Irs1 [cytosol] (R-RNO-1168867) phospho-Irs1 [plasma membrane] (R-RNO-2445090) Irs1 [plasma membrane] (R-RNO-2425392) Irs1 [cytosol] (R-RNO-74769) phospho-Irs1 [cytosol] (R-RNO-74772) phospho-Irs1 [plasma membrane] (R-RNO-198366)	0.737	5
UniProt:Q8N1K5 THMS1			0.737	10
UniProt:Q92918 M4K1			0.72	8
UniProt:B7ZLH0 B7ZLH0			0.718	6
UniProt:Q13444 ADAM15	1	ADAM15 [plasma membrane] (R-HSA-708329)	0.713	4
UniProt:O43561 LAT	3	LAT [plasma membrane] (R-HSA-202322) p-5Y-LAT [plasma membrane] (R-HSA-202364) p-Y200,Y220-LAT [plasma membrane] (R-HSA-434829)	0.708	7
UniProt:Q62245 Sos1	4	Sos1 [plasma membrane] (R-MMU-983559) phospho-Sos1 [cytosol] (R-MMU-109821) Sos1 [cytosol] (R-MMU-443318) Sos1 [cytosol] (R-MMU-64847)	0.704	4
UniProt:Q08209 PPP3CA	2	PPP3CA [cytosol] (R-HSA-201771) PPP3CA [nucleoplasm] (R-HSA-2685599)	0.678	3
UniProt:P21860 ERBB3			0.678	5
UniProt:O43150 ASAP2			0.678	3
UniProt:Q9H204 MED28	1	MED28 [nucleoplasm] (R-HSA-6804546)	0.676	3
UniProt:Q16643 DBN1	1	DBN1 [cytosol] (R-HSA-9714666)	0.674	4
UniProt:P11137 MTAP2			0.672	7
UniProt:O60636 TSN2			0.672	6
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.666	4
UniProt:Q92569 PIK3R3	2	K63polyUb-PIK3R3 [cytosol] (R-HSA-3080574) PIK3R3 [cytosol] (R-HSA-205223)	0.666	4
UniProt:Q9H788 SH24A			0.666	4
UniProt:Q0VD86 INCA1			0.666	4
UniProt:Q9Y2W2 WBP11	1	WBP11 [nucleoplasm] (R-HSA-8867887)	0.666	4
UniProt:Q8IUW3 SPA2L			0.666	4
UniProt:O14744 PRMT5	3	p-Y297,304,307-PRMT5 [nucleoplasm] (R-HSA-5211300) PRMT5 [cytosol] (R-HSA-191876) PRMT5 [nucleoplasm] (R-HSA-5205609)	0.666	4
UniProt:P15498 VAV1	5	p-Y174-VAV1 [cytosol] (R-HSA-437946) VAV1 [plasma membrane] (R-HSA-1045153) VAV1 [cytosol] (R-HSA-195066) p-Y142,Y160,Y174-VAV1 [plasma membrane] (R-HSA-389323) p-Y-VAV1 [cytosol] (R-HSA-9029087)	0.665	3
UniProt:P98078	3	Dab2 [lysosomal membrane] (R-MMU-2980807) Dab2 [cytosol] (R-MMU-8862456) Dab2 [plasma membrane] (R-MMU-2980808)	0.662	4
UniProt:P11021 HSPA5	6	HSPA5 [endoplasmic reticulum lumen] (R-HSA-387190) HSPA5 [extracellular region] (R-HSA-351322) HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [cytosol] (R-HSA-5252115) HSPA5 [nucleoplasm] (R-HSA-5252042) HSPA5 [integral component of lumenal side of endoplasmic reticulum membrane] (R-HSA-985498)	0.659	4
UniProt:Q8N1I0 DOCK4	1	DOCK4 [cytosol] (R-HSA-1012995)	0.659	4
UniProt:Q05397 PTK2	11	p-5Y-PTK2 [cytosol] (R-HSA-5218711) pY-PTK2 [cytosol] (R-HSA-9632393) p-5Y,S732-PTK2 [cytosol] (R-HSA-5229006) p-6Y,S732-PTK2 [cytosol] (R-HSA-5218694) p-Y194,Y397,Y576,Y577-PTK2 [cytosol] (R-HSA-8874613) p-Y194,Y397-PTK2 [cytosol] (R-HSA-8874600) PTK2(773-1052) [cytosol] (R-HSA-202829) PTK2(1-772) [cytosol] (R-HSA-202827) PTK2 [cytosol] (R-HSA-201621) p-Y397-PTK2 [cytosol] (R-HSA-354068) p-6Y-PTK2 [cytosol] (R-HSA-354128)	0.659	4
UniProt:O00459 PIK3R2	2	PIK3R2 [cytosol] (R-HSA-74791) K63polyUb-PIK3R2 [cytosol] (R-HSA-3080554)	0.659	4
UniProt:Q9Y5K6 CD2AP	1	CD2AP [cytosol] (R-HSA-373620)	0.659	3
UniProt:Q9Y2X7 GIT1	2	GIT1 [cytosol] (R-HSA-430326) p-Y383-GIT1 [cytosol] (R-HSA-3928463)	0.659	4
UniProt:P35579 MYH9	1	MYH9 [cytosol] (R-HSA-419173)	0.659	3
UniProt:Q07912 ACK1			0.658	4
UniProt:Q13905 RAPGEF1	3	RAPGEF1 [cytosol] (R-HSA-913472) RAPGEF1 [cytosol] (R-HSA-3008672) RAPGEF1 [endosome] (R-HSA-3008667)	0.658	3
UniProt:P27958 Genome polyprotein	1	POLG [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HCV-8854138)	0.656	3
UniProt:P21802 FGFR2	35	FGFR2 [plasma membrane] (R-HSA-2023840) FGFR2 IIIa TM [extracellular region] (R-HSA-8851703) FGFR2(22-767)-CCDC6(102-474) fusion [plasma membrane] (R-HSA-8853137) FGFR2(2-822)-CIT(927-2027) fusion [plasma membrane] (R-HSA-8853154) FGFR2(22-768)-BICC1(80-974) fusion [plasma membrane] (R-HSA-8853123) FGFR2(22-767)-AHCYL1(108-530) fusion [plasma membrane] (R-HSA-8853158) FGFR2(22-767)-OFD1(38-1012) fusion [plasma membrane] (R-HSA-8853150) FGFR2(22-767)-CASP7(1-303) fusion [plasma membrane] (R-HSA-8853153) FGFR2(22-767)-AFF3(292-1226) fusion [plasma membrane] (R-HSA-8853139) FGFR2(22-767)-CCAR(51-923) fusion [plasma membrane] (R-HSA-8853159) FGFR2 N549H [plasma membrane] (R-HSA-2033296) FGFR2 N549K [plasma membrane] (R-HSA-1637910) FGFR2 K660N [plasma membrane] (R-HSA-1637905) FGFR2 K660M [plasma membrane] (R-HSA-1637902) FGFR2 K660E [plasma membrane] (R-HSA-1637900) FGFR2 S267P [plasma membrane] (R-HSA-1637920) FGFR2 L764fs4 [plasma membrane] (R-HSA-1637908) FGFR2 W290C [plasma membrane] (R-HSA-1637929) p-6Y FGFR2(22-767)-CCDC6(102-474) fusion [plasma membrane] (R-HSA-8853134) p-6Y FGFR2(22-768)-BICC1(80-974) fusion [plasma membrane] (R-HSA-8853146) p-6Y FGFR2(2-822)-CIT(927-2027) fusion [plasma membrane] (R-HSA-8853132) p-6Y FGFR2(22-767)-AHCYL1(108-530) fusion [plasma membrane] (R-HSA-8853121) p-6Y FGFR2(22-767)-OFD1(38-1012) fusion [plasma membrane] (R-HSA-8853136) p-6Y FGFR2(22-767)-AFF3(292-1226) fusion [plasma membrane] (R-HSA-8853130) p-6Y FGFR2(22-767)-CASP7(1-303) fusion [plasma membrane] (R-HSA-8853133) p-6Y FGFR2 (22-767)-CCAR(51-923) fusion [plasma membrane] (R-HSA-8853141) p-8Y-FGFR2 K660N [plasma membrane] (R-HSA-2033301) p-8Y-FGFR2 N549H [plasma membrane] (R-HSA-2033304) p-8Y-FGFR2 N549K [plasma membrane] (R-HSA-2033306) p-8Y-FGFR2 [plasma membrane] (R-HSA-2029874) p-8Y-FGFR2 S267P [plasma membrane] (R-HSA-2029879) p-8Y-FGFR2 W290C [plasma membrane] (R-HSA-2029875) phosphorylated FGFR2 L764fs4 [plasma membrane] (R-HSA-2071957) p-8Y-FGFR2 K660E [plasma membrane] (R-HSA-2033298) p-8Y-FGFR2 K660M [plasma membrane] (R-HSA-2033300)	0.655	5
UniProt:P29350 PTPN6	5	PTPN6 [extracellular region] (R-HSA-6806315) PTPN6 [tertiary granule lumen] (R-HSA-6800952) PTPN6 [specific granule lumen] (R-HSA-6799641) PTPN6 [nucleoplasm] (R-HSA-9008911) PTPN6 [cytosol] (R-HSA-197938)	0.646	3
UniProt:Q96P48 ARAP1	2	ARAP1 [cytosol] (R-HSA-3211582) p-Y231-ARAP1 [cytosol] (R-HSA-8848869)	0.643	4
UniProt:A6NGB9 WIPF3	1	WIPF3 [cytosol] (R-HSA-2197670)	0.643	4
UniProt:Q38SD2 LRRK1			0.643	3
UniProt:Q96JJ3 ELMO2	1	ELMO2 [cytosol] (R-HSA-372642)	0.643	4
UniProt:Q14247 CTTN	2	p-S113-CTTN [cytosol] (R-HSA-442842) CTTN [cytosol] (R-HSA-201894)	0.643	3
UniProt:P18031 PTPN1	1	PTPN1 [cytosol] (R-HSA-210625)	0.642	4
UniProt:Q8N1K5-1 THEMIS			0.639	10
UniProt:O14939 PLD2	2	PLD2 [endoplasmic reticulum membrane] (R-HSA-1498791) PLD2 [plasma membrane] (R-HSA-2029075)	0.635	4
UniProt:Q15027 ACAP1			0.635	3
UniProt:P06400 RB1	394	RB1 C706F [nucleoplasm] (R-HSA-9659812) RB1 R661W [nucleoplasm] (R-HSA-9659801) RB1 N480del [nucleoplasm] (R-HSA-9659792) RB1 C706Y [nucleoplasm] (R-HSA-9659821) RB1 R661Q [nucleoplasm] (R-HSA-9659807) RB1 I703_E737del [nucleoplasm] (R-HSA-9661065) RB1 R830_G887del [cytosol] (R-HSA-9661059) RB1 K791* [cytosol] (R-HSA-9662284) RB1 Q176* [cytosol] (R-HSA-9661774) RB1 S114* [cytosol] (R-HSA-9661775) RB1 K765* [cytosol] (R-HSA-9662281) RB1 W99* [cytosol] (R-HSA-9661769) RB1 S149* [cytosol] (R-HSA-9661770) RB1 E166* [cytosol] (R-HSA-9661767) RB1 G100* [cytosol] (R-HSA-9661763) RB1 E125* [cytosol] (R-HSA-9661784) RB1 Q121* [cytosol] (R-HSA-9661780) RB1 E184* [cytosol] (R-HSA-9661781) RB1 E137* [cytosol] (R-HSA-9661782) RB1 K745* [cytosol] (R-HSA-9662288) RB1 E209* [cytosol] (R-HSA-9661776) RB1 S618* [cytosol] (R-HSA-9662240) RB1 S463* [cytosol] (R-HSA-9662241) RB1 K720* [cytosol] (R-HSA-9662269) RB1 K429* [cytosol] (R-HSA-9662270) RB1 K652* [cytosol] (R-HSA-9662271) RB1 K715* [cytosol] (R-HSA-9662264) RB1 K615* [cytosol] (R-HSA-9662266) RB1 K412* [cytosol] (R-HSA-9662261) RB1 S567* [cytosol] (R-HSA-9662218) RB1 S807* [cytosol] (R-HSA-9662212) RB1 R467* [cytosol] (R-HSA-9662213) RB1 S834* [cytosol] (R-HSA-9662210) RB1 S576* [cytosol] (R-HSA-9662237) RB1 S758* [cytosol] (R-HSA-9662232) RB1 R7Pfs24 [cytosol] (R-HSA-9686292) RB1 S443 [cytosol] (R-HSA-9662230) RB1 S648* [cytosol] (R-HSA-9662224) RB1 S391* [cytosol] (R-HSA-9662225) RB1 S829* [cytosol] (R-HSA-9662226) RB1 D32Tfs33 [cytosol] (R-HSA-9688044) RB1 Y651Ifs7 [cytosol] (R-HSA-9688045) RB1 K143Mfs19 [cytosol] (R-HSA-9688046) RB1 V754Sfs4 [cytosol] (R-HSA-9688047) RB1 L44Rfs4 [cytosol] (R-HSA-9688040) RB1 E97Gfs13 [cytosol] (R-HSA-9688041) RB1 I679* [cytosol] (R-HSA-9688042) RB1 W195* [cytosol] (R-HSA-9689579) RB1 G100Efs11 [cytosol] (R-HSA-9688043) RB1 S648Tfs4 [cytosol] (R-HSA-9688036) RB1 H281Qfs6 [cytosol] (R-HSA-9688037) RB1 Q384 [cytosol] (R-HSA-9661925) RB1 S182Yfs2 [cytosol] (R-HSA-9688038) RB1 L343Sfs3 [cytosol] (R-HSA-9688039) RB1 L337Wfs12 [cytosol] (R-HSA-9688032) RB1 S318 [cytosol] (R-HSA-9688033) RB1 N627Mfs16 [cytosol] (R-HSA-9688034) RB1 N290Kfs20 [cytosol] (R-HSA-9688035) RB1 F299Lfs4 [cytosol] (R-HSA-9688060) RB1 Q637 [cytosol] (R-HSA-9662460) RB1 L76* [cytosol] (R-HSA-9688061) RB1 Q762* [cytosol] (R-HSA-9662461) RB1 Y655Lfs4 [cytosol] (R-HSA-9688062) RB1 N480Kfs13 [cytosol] (R-HSA-9688063) RB1 Q444* [cytosol] (R-HSA-9662463) RB1 T77Lfs34 [cytosol] (R-HSA-9688056) RB1 E747Gfs3 [cytosol] (R-HSA-9688057) RB1 M825* [cytosol] (R-HSA-9688058) RB1 L649Ffs11 [cytosol] (R-HSA-9688059) RB1 N472Ifs6 [cytosol] (R-HSA-9688052) RB1 Y813Kfs12 [cytosol] (R-HSA-9688053) RB1 I324Mfs17 [cytosol] (R-HSA-9688054) RB1 M460Ifs3 [cytosol] (R-HSA-9688055) RB1 Y655Ifs3 [cytosol] (R-HSA-9688048) RB1 L769Cfs41 [cytosol] (R-HSA-9688049) RB1 P28Lfs37 [cytosol] (R-HSA-9688050) RB1 E677Dfs19 [cytosol] (R-HSA-9688051) RB1 P370Lfs10 [cytosol] (R-HSA-9688012) RB1 N593Tfs11 [cytosol] (R-HSA-9688013) RB1 K329 [cytosol] (R-HSA-9661901) RB1 S249Ffs22 [cytosol] (R-HSA-9688014) RB1 K240 [cytosol] (R-HSA-9661902) RB1 L199Ffs4 [cytosol] (R-HSA-9688015) RB1 P253Gfs5 [cytosol] (R-HSA-9688008) RB1 K289* [cytosol] (R-HSA-9661896) RB1 S360Pfs2 [cytosol] (R-HSA-9688009) RB1 E323Kfs9 [cytosol] (R-HSA-9688010) RB1 L326* [cytosol] (R-HSA-9688011) RB1 P808Kfs12 [cytosol] (R-HSA-9688004) RB1 D584Nfs2 [cytosol] (R-HSA-9688005) RB1 N406Kfs4 [cytosol] (R-HSA-9688006) RB1 K417Wfs23 [cytosol] (R-HSA-9688007) RB1 L797Ffs18 [cytosol] (R-HSA-9688000) RB1 Q266Hfs2 [cytosol] (R-HSA-9688001) RB1 R255* [cytosol] (R-HSA-9661889) RB1 K4* [cytosol] (R-HSA-9661377) RB1 P641Afs12 [cytosol] (R-HSA-9688002) RB1 V450Sfs13 [cytosol] (R-HSA-9688003) RB1 K524Rfs28 [cytosol] (R-HSA-9688028) RB1 E280 [cytosol] (R-HSA-9661916) RB1 M825Ifs13 [cytosol] (R-HSA-9688029) RB1 M761Nfs21 [cytosol] (R-HSA-9688030) RB1 A11Rfs20 [cytosol] (R-HSA-9688031) RB1 E275 [cytosol] (R-HSA-9661919) RB1 A635Gfs6 [cytosol] (R-HSA-9688024) RB1 Q266 [cytosol] (R-HSA-9661912) RB1 I66Yfs11 [cytosol] (R-HSA-9688025) RB1 Q257 [cytosol] (R-HSA-9661913) RB1 P39Rfs26 [cytosol] (R-HSA-9688026) RB1 T664Nfs4 [cytosol] (R-HSA-9688027) RB1 Y771Lfs24 [cytosol] (R-HSA-9688020) RB1 R320Dfs12 [cytosol] (R-HSA-9688021) RB1 E282* [cytosol] (R-HSA-9661909) RB1 L277Pfs9 [cytosol] (R-HSA-9688022) RB1 I124 [cytosol] (R-HSA-9688023) RB1 N803Tfs7 [cytosol] (R-HSA-9688016) RB1 M386Ifs11 [cytosol] (R-HSA-9688017) RB1 E72Vfs34 [cytosol] (R-HSA-9688018) RB1 R150Kfs7 [cytosol] (R-HSA-9688019) RB1 L743* [cytosol] (R-HSA-9687980) RB1 R7Efs58 [cytosol] (R-HSA-9687981) RB1 T140Nfs6 [cytosol] (R-HSA-9687982) RB1 D479Efs16 [cytosol] (R-HSA-9687983) RB1 L199 [cytosol] (R-HSA-9661871) RB1 G801* [cytosol] (R-HSA-9662377) RB1 S215* [cytosol] (R-HSA-9661866) RB1 G435* [cytosol] (R-HSA-9662368) RB1 G581* [cytosol] (R-HSA-9662369) RB1 L134* [cytosol] (R-HSA-9687996) RB1 Y529Lfs26 [cytosol] (R-HSA-9687997) RB1 S816Qfs10 [cytosol] (R-HSA-9687998) RB1 E693Nfs3 [cytosol] (R-HSA-9687999) RB1 D346Rfs4 [cytosol] (R-HSA-9687992) RB1 Q35* [cytosol] (R-HSA-9661368) RB1 I806Lfs10 [cytosol] (R-HSA-9687993) RB1 E54 [cytosol] (R-HSA-9661369) RB1 L199Yfs2 [cytosol] (R-HSA-9687994) RB1 E48 [cytosol] (R-HSA-9661370) RB1 N854* [cytosol] (R-HSA-9687995) RB1 W75* [cytosol] (R-HSA-9661371) RB1 L389Ffs3 [cytosol] (R-HSA-9687988) RB1 S230 [cytosol] (R-HSA-9661876) RB1 H483Sfs10 [cytosol] (R-HSA-9687989) RB1 S842 [cytosol] (R-HSA-9687990) RB1 W78* [cytosol] (R-HSA-9661366) RB1 G449Efs8 [cytosol] (R-HSA-9687991) RB1 K63 [cytosol] (R-HSA-9661367) RB1 K537Nfs14 [cytosol] (R-HSA-9687984) RB1 L206 [cytosol] (R-HSA-9661872) RB1 K63Rfs38 [cytosol] (R-HSA-9687985) RB1 P732Lfs12 [cytosol] (R-HSA-9687986) RB1 L158* [cytosol] (R-HSA-9661874) RB1 A562Hfs49 [cytosol] (R-HSA-9687987) RB1 E72 [cytosol] (R-HSA-9661363) RB1 G540Afs3 [cytosol] (R-HSA-9688172) RB1 N328Ifs4 [cytosol] (R-HSA-9688173) RB1 E843* [cytosol] (R-HSA-9662573) RB1 L385* [cytosol] (R-HSA-9688174) RB1 E464* [cytosol] (R-HSA-9662574) RB1 N123Tfs2 [cytosol] (R-HSA-9688175) RB1 E112Dfs6 [cytosol] (R-HSA-9688168) RB1 E748* [cytosol] (R-HSA-9662568) RB1 M148Ifs8 [cytosol] (R-HSA-9688169) RB1 R661 [cytosol] (R-HSA-9688170) RB1 Y453* [cytosol] (R-HSA-9688164) RB1 K95* [cytosol] (R-HSA-9661540) RB1 M484Vfs8 [cytosol] (R-HSA-9688165) RB1 E533 [cytosol] (R-HSA-9662565) RB1 G86* [cytosol] (R-HSA-9661541) RB1 V654Sfs14 [cytosol] (R-HSA-9688166) RB1 E747 [cytosol] (R-HSA-9662566) RB1 E79* [cytosol] (R-HSA-9661542) RB1 C553Wfs53 [cytosol] (R-HSA-9688167) RB1 E677 [cytosol] (R-HSA-9662567) RB1 K96* [cytosol] (R-HSA-9661543) RB1 C102Yfs7 [cytosol] (R-HSA-9688160) RB1 E737 [cytosol] (R-HSA-9662560) RB1 E97* [cytosol] (R-HSA-9661536) RB1 R579Qfs29 [cytosol] (R-HSA-9688161) RB1 A525Pfs7 [cytosol] (R-HSA-9688162) RB1 L542Kfs11 [cytosol] (R-HSA-9688163) RB1 F482Sfs10 [cytosol] (R-HSA-9688188) RB1 L797* [cytosol] (R-HSA-9688189) RB1 P250Afs16 [cytosol] (R-HSA-9688190) RB1 S194Ffs7 [cytosol] (R-HSA-9688191) RB1 N623Qfs15 [cytosol] (R-HSA-9688184) RB1 T9Rfs56 [cytosol] (R-HSA-9688185) RB1 Y813Qfs10 [cytosol] (R-HSA-9688187) RB1 I768Cfs23 [cytosol] (R-HSA-9688180) RB1 L477Mfs17 [cytosol] (R-HSA-9688181) RB1 E675 [cytosol] (R-HSA-9662581) RB1 V654Cfs4 [cytosol] (R-HSA-9688182) RB1 F650Lfs5 [cytosol] (R-HSA-9688183) RB1 P39Sfs10 [cytosol] (R-HSA-9688176) RB1 H281Sfs2 [cytosol] (R-HSA-9688177) RB1 E551* [cytosol] (R-HSA-9662577) RB1 C61Vfs4 [cytosol] (R-HSA-9688178) RB1 D145Ifs8 [cytosol] (R-HSA-9688179) RB1 M148Hfs9 [cytosol] (R-HSA-9688140) RB1 E837 [cytosol] (R-HSA-9662540) RB1 L158Mfs19 [cytosol] (R-HSA-9688141) RB1 L832Ffs5 [cytosol] (R-HSA-9688142) RB1 E440* [cytosol] (R-HSA-9662542) RB1 D224Afs40 [cytosol] (R-HSA-9688136) RB1 P822Qfs4 [cytosol] (R-HSA-9688137) RB1 M148Vfs8 [cytosol] (R-HSA-9688138) RB1 L670Cfs7 [cytosol] (R-HSA-9688139) RB1 E465* [cytosol] (R-HSA-9662532) RB1 S414Kfs14 [cytosol] (R-HSA-9688133) RB1 K548Nfs3 [cytosol] (R-HSA-9688134) RB1 L135Tfs5 [cytosol] (R-HSA-9688135) RB1 Q207Tfs5 [cytosol] (R-HSA-9688128) RB1 Q384Tfs11 [cytosol] (R-HSA-9688129) RB1 L797Ffs14 [cytosol] (R-HSA-9688130) RB1 P232Rfs4 [cytosol] (R-HSA-9688131) RB1 T497Hfs22 [cytosol] (R-HSA-9688156) RB1 E817* [cytosol] (R-HSA-9662556) RB1 N367* [cytosol] (R-HSA-9688157) RB1 L809Rfs17 [cytosol] (R-HSA-9688158) RB1 E693 [cytosol] (R-HSA-9662558) RB1 K80* [cytosol] (R-HSA-9661534) RB1 W99Lfs11 [cytosol] (R-HSA-9688159) RB1 A15Pfs3 [cytosol] (R-HSA-9688152) RB1 Y239Lfs25 [cytosol] (R-HSA-9688153) RB1 D571Lfs41 [cytosol] (R-HSA-9688154) RB1 N186Ifs6 [cytosol] (R-HSA-9688155) RB1 E837Dfs12 [cytosol] (R-HSA-9688148) RB1 E672* [cytosol] (R-HSA-9662548) RB1 H483Yfs9 [cytosol] (R-HSA-9688149) RB1 R775Gfs35 [cytosol] (R-HSA-9688150) RB1 E580* [cytosol] (R-HSA-9662550) RB1 G617Rfs36 [cytosol] (R-HSA-9688151) RB1 E492 [cytosol] (R-HSA-9662551) RB1 A333Ffs13 [cytosol] (R-HSA-9688144) RB1 L564Sfs47 [cytosol] (R-HSA-9688145) RB1 D156Vfs19 [cytosol] (R-HSA-9688147) RB1 C438Vfs19 [cytosol] (R-HSA-9688108) RB1 C278* [cytosol] (R-HSA-9688109) RB1 E209Vfs3 [cytosol] (R-HSA-9688110) RB1 T116Lfs8 [cytosol] (R-HSA-9688111) RB1 R698Afs22 [cytosol] (R-HSA-9688104) RB1 V419 [cytosol] (R-HSA-9688105) RB1 I415Nfs13 [cytosol] (R-HSA-9688106) RB1 Y173Ffs11 [cytosol] (R-HSA-9688107) RB1 N133Tfs3 [cytosol] (R-HSA-9688100) RB1 M695Rfs10 [cytosol] (R-HSA-9688101) RB1 R418Sfs9 [cytosol] (R-HSA-9688102) RB1 Q689 [cytosol] (R-HSA-9662502) RB1 A74Efs4 [cytosol] (R-HSA-9688103) RB1 W99Yfs5 [cytosol] (R-HSA-9688096) RB1 G442Dfs15 [cytosol] (R-HSA-9688097) RB1 N258Efs11 [cytosol] (R-HSA-9688098) RB1 S182Ifs3 [cytosol] (R-HSA-9688099) RB1 Q436 [cytosol] (R-HSA-9662499) RB1 Q395Pfs11 [cytosol] (R-HSA-9688124) RB1 Y606Lfs47 [cytosol] (R-HSA-9688125) RB1 E539* [cytosol] (R-HSA-9662525) RB1 L317* [cytosol] (R-HSA-9688126) RB1 F104Lfs7 [cytosol] (R-HSA-9688127) RB1 E691 [cytosol] (R-HSA-9662527) RB1 D340Yfs5 [cytosol] (R-HSA-9688120) RB1 K740Tfs10 [cytosol] (R-HSA-9688121) RB1 H483Ifs12 [cytosol] (R-HSA-9688122) RB1 R611Lfs43 [cytosol] (R-HSA-9688123) RB1 V291Ifs9 [cytosol] (R-HSA-9688116) RB1 N133 [cytosol] (R-HSA-9688117) RB1 R334* [cytosol] (R-HSA-9688118) RB1 D697Qfs23 [cytosol] (R-HSA-9688119) RB1 L647Ffs5 [cytosol] (R-HSA-9688112) RB1 I723Nfs28 [cytosol] (R-HSA-9688113) RB1 L486Ifs6 [cytosol] (R-HSA-9688114) RB1 S565* [cytosol] (R-HSA-9688115) RB1 Y529Tfs3 [cytosol] (R-HSA-9688076) RB1 Q631 [cytosol] (R-HSA-9662476) RB1 S318Nfs13 [cytosol] (R-HSA-9688077) RB1 D856Efs17 [cytosol] (R-HSA-9688078) RB1 P595Lfs16 [cytosol] (R-HSA-9688079) RB1 P777Lfs33 [cytosol] (R-HSA-9688072) RB1 G310Dfs22 [cytosol] (R-HSA-9688073) RB1 P250Sfs20 [cytosol] (R-HSA-9688074) RB1 Q850* [cytosol] (R-HSA-9662474) RB1 I124Rfs6 [cytosol] (R-HSA-9688075) RB1 Q702 [cytosol] (R-HSA-9662475) RB1 E748Dfs6 [cytosol] (R-HSA-9688068) RB1 Q736 [cytosol] (R-HSA-9662468) RB1 R798Qfs4 [cytosol] (R-HSA-9688069) RB1 S588Ffs6 [cytosol] (R-HSA-9688070) RB1 K574* [cytosol] (R-HSA-9688071) RB1 D156Mfs19 [cytosol] (R-HSA-9688064) RB1 Y771Cfs23 [cytosol] (R-HSA-9688065) RB1 I66Dfs44 [cytosol] (R-HSA-9688066) RB1 Q685 [cytosol] (R-HSA-9662466) RB1 E125Kfs11 [cytosol] (R-HSA-9688067) RB1 Y655Lfs13 [cytosol] (R-HSA-9688092) RB1 R828Kfs10 [cytosol] (R-HSA-9688093) RB1 Y659Ifs4 [cytosol] (R-HSA-9688094) RB1 Q846* [cytosol] (R-HSA-9662494) RB1 E97Nfs14 [cytosol] (R-HSA-9688095) RB1 Q770 [cytosol] (R-HSA-9662495) RB1 C666* [cytosol] (R-HSA-9688088) RB1 Q471* [cytosol] (R-HSA-9662488) RB1 R71Efs39 [cytosol] (R-HSA-9688089) RB1 Q504 [cytosol] (R-HSA-9662489) RB1 R798Tfs17 [cytosol] (R-HSA-9688090) RB1 Q639 [cytosol] (R-HSA-9662490) RB1 N328* [cytosol] (R-HSA-9688091) RB1 S576Rfs34 [cytosol] (R-HSA-9688084) RB1 T726Nfs25 [cytosol] (R-HSA-9688085) RB1 Q597* [cytosol] (R-HSA-9662485) RB1 I532Nfs57 [cytosol] (R-HSA-9688086) RB1 K577Rfs34 [cytosol] (R-HSA-9688087) RB1 R73Sfs36 [cytosol] (R-HSA-9688080) RB1 E413Kfs4 [cytosol] (R-HSA-9688081) RB1 K844Sfs5 [cytosol] (R-HSA-9688082) RB1 A17Pfs3 [cytosol] (R-HSA-9688083) RB1 Q395* [cytosol] (R-HSA-9660655) RB1 L523* [cytosol] (R-HSA-9662176) RB1 R251* [cytosol] (R-HSA-9660640) RB1 L389* [cytosol] (R-HSA-9662178) RB1 Q217* [cytosol] (R-HSA-9660668) RB1 Q344* [cytosol] (R-HSA-9660669) RB1 S634* [cytosol] (R-HSA-9662207) RB1 S565* [cytosol] (R-HSA-9662200) RB1 S397* [cytosol] (R-HSA-9662202) RB1 S838* [cytosol] (R-HSA-9662203) RB1 R556* [cytosol] (R-HSA-9660661) RB1 R787* [cytosol] (R-HSA-9660656) RB1 G304* [cytosol] (R-HSA-9662152) RB1 W516* [cytosol] (R-HSA-9662660) RB1 W681* [cytosol] (R-HSA-9662661) RB1 E322* [cytosol] (R-HSA-9662149) RB1 W563* [cytosol] (R-HSA-9662656) RB1 L550* [cytosol] (R-HSA-9662173) RB1 R552* [cytosol] (R-HSA-9660637) RB1 L512* [cytosol] (R-HSA-9662168) RB1 R455* [cytosol] (R-HSA-9660632) RB1 R763* [cytosol] (R-HSA-9662681) RB1 L779* [cytosol] (R-HSA-9662169) RB1 R445* [cytosol] (R-HSA-9660633) RB1 R544* [cytosol] (R-HSA-9662677) RB1 R320* [cytosol] (R-HSA-9660630) RB1 L832* [cytosol] (R-HSA-9662167) RB1 Y498* [cytosol] (R-HSA-9662634) RB1 Y446* [cytosol] (R-HSA-9662628) RB1 Y655* [cytosol] (R-HSA-9662629) RB1 E323* [cytosol] (R-HSA-9662142) RB1 E364* [cytosol] (R-HSA-9662143) RB1 C489* [cytosol] (R-HSA-9662649) RB1 G310* [cytosol] (R-HSA-9662137) RB1 L335* [cytosol] (R-HSA-9662139) RB1 E313* [cytosol] (R-HSA-9662133) RB1 E315* [cytosol] (R-HSA-9662131) RB1 D479Vfs14 [cytosol] (R-HSA-9688204) RB1 C489Lfs5 [cytosol] (R-HSA-9688205) RB1 Y454* [cytosol] (R-HSA-9662605) RB1 E137Rfs3 [cytosol] (R-HSA-9688206) RB1 L676Ffs16 [cytosol] (R-HSA-9688207) RB1 Y728* [cytosol] (R-HSA-9662607) RB1 I799Ffs11 [cytosol] (R-HSA-9688200) RB1 D346Vfs17 [cytosol] (R-HSA-9688201) RB1 F514Pfs8 [cytosol] (R-HSA-9688202) RB1 N593Sfs5 [cytosol] (R-HSA-9688203) RB1 T58Yfs52 [cytosol] (R-HSA-9688196) RB1 N522Ifs2 [cytosol] (R-HSA-9688197) RB1 C553Vfs58 [cytosol] (R-HSA-9688198) RB1 P609Cfs43 [cytosol] (R-HSA-9688199) RB1 N269* [cytosol] (R-HSA-9688192) RB1 E287Rfs2 [cytosol] (R-HSA-9688193) RB1 E492Lfs4 [cytosol] (R-HSA-9688194) RB1 Q383Nfs3 [cytosol] (R-HSA-9688195) RB1 Y606 [cytosol] (R-HSA-9662617) RB1 Y756* [cytosol] (R-HSA-9662619) RB1 Y790* [cytosol] (R-HSA-9662612) RB1 T502Nfs17 [cytosol] (R-HSA-9688208) RB1 Y709 [cytosol] (R-HSA-9662608) RB1 Y749* [cytosol] (R-HSA-9662611) RB1 T738_R775del [nucleoplasm] (R-HSA-9661042) hyperphosphorylated RB1 [nucleoplasm] (R-HSA-188389) RB1 [cytosol] (R-HSA-9660621) p-S249-RB1 [nucleoplasm] (R-HSA-9687343) p-S230-RB1 [nucleoplasm] (R-HSA-9687336) p-T356-RB1 [nucleoplasm] (R-HSA-9687339) p-T826-RB1 [nucleoplasm] (R-HSA-9687334) p-S252-RB1 [nucleoplasm] (R-HSA-9687335) p-S807-RB1 [nucleoplasm] (R-HSA-9687356) p-T821-RB1 [nucleoplasm] (R-HSA-9687357) p-S795-RB1 [nucleoplasm] (R-HSA-69226) p-S612-RB1 [nucleoplasm] (R-HSA-9687352) p-S780-RB1 [nucleoplasm] (R-HSA-9687353) p-S811-RB1 [nucleoplasm] (R-HSA-9687354) RB1 [nucleoplasm] (R-HSA-68642) p-S788-RB1 [nucleoplasm] (R-HSA-9687347) p-S608-RB1 [nucleoplasm] (R-HSA-9687351) p-T373-RB1 [nucleoplasm] (R-HSA-9687355)	0.61	4
UniProt:Q8NFH8-2 REPS2			0.602	8
UniProt:O14672 ADAM10	6	ADAM10 [plasma membrane] (R-HSA-157237) ADAM10(215-824) [plasma membrane] (R-HSA-179885) ADAM10 [endoplasmic reticulum lumen] (R-HSA-8956768) p-ADAM10 [endoplasmic reticulum lumen] (R-HSA-8956999) ADAM10 [tertiary granule membrane] (R-HSA-6800992) ADAM10 [specific granule membrane] (R-HSA-6799566)	0.602	5
UniProt:O15357 INPPL1	1	INPPL1 [cytosol] (R-HSA-913354)	0.597	4
UniProt:P34152 Ptk2	13	p-Y428-FAK1 [cytosol] (R-MMU-3928397) phospho-Ptk2 [cytosol] (R-MMU-9632393) phospho-Ptk2 [cytosol] (R-MMU-354128) phospho-Ptk2 [cytosol] (R-MMU-354068) Ptk2 [cytosol] (R-MMU-201621) Ptk2 [cytosol] (R-MMU-202827) Ptk2 [cytosol] (R-MMU-202829) phospho-Ptk2 [cytosol] (R-MMU-8874600) phospho-Ptk2 [cytosol] (R-MMU-8874613) phospho-Ptk2 [cytosol] (R-MMU-5218694) phospho-Ptk2 [cytosol] (R-MMU-5229006) phospho-Ptk2 [cytosol] (R-MMU-5218711) Fak1 [cytosol] (R-MMU-3928448)	0.597	3
UniProt:Q9ESJ4	1	Nckipsd [cytosol] (R-MMU-2197671)	0.593	8
UniProt:Q5SQ64 LY6G6F	2	LY6G6F [plasma membrane] (R-HSA-8862974) LY6G6F [platelet alpha granule membrane] (R-HSA-8862968)	0.591	3
UniProt:O43597 SPRY2	8	p-Y55-SPRY2 [cytosol] (R-HSA-182950) p-S111,S120-SPRY2 [cytosol] (R-HSA-1295590) SPRY2 [plasma membrane] (R-HSA-182924) SPRY2 [cytosol] (R-HSA-182949) p-S112,S115-SPRY2 [cytosol] (R-HSA-1295619) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-934555) p-S112,S121-SPRY2 [plasma membrane] (R-HSA-934595) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-1295629)	0.591	3
UniProt:O92972 POLG			0.589	2
UniProt:Q15427 SF3B4	1	SF3B4 [nucleoplasm] (R-HSA-71975)	0.573	2
UniProt:Q15303 ERBB4			0.573	7
UniProt:O14490 DLGAP1	1	DLGAP1 [plasma membrane] (R-HSA-6794239)	0.573	3
UniProt:Q9BYB0 SHANK3	1	SHANK3 [cytosol] (R-HSA-6794277)	0.573	2
UniProt:Q8IVH8 M4K3			0.573	2
UniProt:O15056 SYNJ2	1	SYNJ2 [cytosol] (R-HSA-1806193)	0.573	2
UniProt:P98082 DAB2	3	DAB2 [lysosomal membrane] (R-HSA-2980807) DAB2 [cytosol] (R-HSA-8862456) DAB2 [plasma membrane] (R-HSA-2980808)	0.573	2
UniProt:P55072 VCP	8	VCP [endoplasmic reticulum membrane] (R-HSA-8943105) Me3K315-VCP [cytosol] (R-HSA-8932209) VCP [nucleoplasm] (R-HSA-5643745) VCP [ficolin-1-rich granule lumen] (R-HSA-6800425) VCP [azurophil granule lumen] (R-HSA-6800438) VCP [extracellular region] (R-HSA-6806191) VCP [secretory granule lumen] (R-HSA-6801039) VCP [cytosol] (R-HSA-1181251)	0.57	3
UniProt:Q8TE12 LMX1A			0.57	3
UniProt:Q5BJH2-2 TMEM128			0.57	3
UniProt:Q9NPB6-2 PARD6A			0.57	3
UniProt:Q8WXH5 SOCS4	1	SOCS4 [cytosol] (R-HSA-8936109)	0.57	3
UniProt:Q07869 PPARA	2	PPARA [nucleoplasm] (R-HSA-400186) SUMO1-K185-PPARA [nucleoplasm] (R-HSA-4341099)	0.57	3
UniProt:P14868 DARS1	1	DARS [cytosol] (R-HSA-379605)	0.564	2
UniProt:Q15109 AGER	1	AGER [plasma membrane] (R-HSA-197639)	0.564	2
UniProt:P21333 FLNA	3	p-S2152-FLNA [cytosol] (R-HSA-5669246) FLNA [extracellular region] (R-HSA-350712) FLNA [cytosol] (R-HSA-210019)	0.564	2
UniProt:O75369 FLNB	1	FLNB [cytosol] (R-HSA-354163)	0.564	2
UniProt:P19174 PLCG1	6	PLCG1 [plasma membrane] (R-HSA-167682) p-4Y-PLCG1 [plasma membrane] (R-HSA-167679) PLCG1 [cytosol] (R-HSA-202320) p-Y771,Y783,Y1254-PLCG1 [cytosol] (R-HSA-202357) p-Y771,Y783-PLCG1 [plasma membrane] (R-HSA-1169084) p-Y-PLCG1 [cytosol] (R-HSA-9029082)	0.564	2
UniProt:Q9H0X6 RN208			0.556	3
UniProt:Q9BWF3-2 RBM4			0.556	3
UniProt:Q9NRF2-2 SH2B1	1	SH2B1-2 [cytosol] (R-HSA-1675482)	0.556	3
UniProt:Q7Z783 Q7Z783			0.556	3
UniProt:Q13829 TNFAIP1	1	TNFAIP1 [cytosol] (R-HSA-9696531)	0.556	3
UniProt:Q14693 LPIN1	3	p-S106-LPIN1 [nucleoplasm] (R-HSA-4419936) LPIN1 [nuclear envelope] (R-HSA-4419927) LPIN1 [endoplasmic reticulum membrane] (R-HSA-549157)	0.556	3
UniProt:Q6P1W5 CA094			0.556	3
UniProt:Q9P2A4 ABI3			0.556	3
UniProt:Q13352 ITGB3BP	2	ITGB3BP [nucleoplasm] (R-HSA-606325) ITGB3BP [cytosol] (R-HSA-3006405)	0.556	3
UniProt:Q9NQC1-2 JADE2			0.556	3
UniProt:Q9UI10 EIF2B4	1	EIF2B4 [cytosol] (R-HSA-72521)	0.556	3
UniProt:A5D8V6 VPS37C	1	VPS37C [endosome membrane] (R-HSA-184438)	0.556	3
UniProt:Q15428 SF3A2	1	SF3A2 [nucleoplasm] (R-HSA-71964)	0.556	3
UniProt:Q9BRK4 LZTS2			0.556	3
UniProt:P52566 ARHGDIB	1	ARHGDIB [cytosol] (R-HSA-195081)	0.556	3
UniProt:Q14457 BECN1	3	BECN1 [cytosol] (R-HSA-1632841) K63polyUb-BECN1 [cytosol] (R-HSA-6782989) p-S15-BECN1 [cytosol] (R-HSA-5682391)	0.556	3
UniProt:Q04864 REL	2	REL [nucleoplasm] (R-HSA-1168585) REL [cytosol] (R-HSA-1168579)	0.556	3
UniProt:Q9BUN5-3 CCDC28B			0.556	3
UniProt:Q12929 EPS8	1	EPS8 [cytosol] (R-HSA-9662382)	0.556	3
UniProt:Q86UU5 GGN			0.556	3
UniProt:Q9BYN7 ZN341			0.556	3
UniProt:Q3LI72 KRTAP19-5	1	KRTAP19-5 [cytosol] (R-HSA-6810300)	0.556	3
UniProt:Q6DHY5 TBC3G			0.556	3
UniProt:Q96RU7 TRIB3	3	TRIB3 [cytosol] (R-HSA-162411) TRIB3 [plasma membrane] (R-HSA-199447) TRIB3 [nucleoplasm] (R-HSA-9635877)	0.556	3
UniProt:P25791 LMO2	1	LMO2 [nucleoplasm] (R-HSA-8956513)	0.556	3
UniProt:Q8NFB2 T185A			0.556	3
UniProt:Q8IX15-3 HOMEZ			0.556	3
UniProt:Q6XD76 ASCL4			0.556	3
UniProt:P42681 TXK	3	TXK [cytosol] (R-HSA-3448733) p-Y91,Y420-TXK [cytosol] (R-HSA-3448740) p-Y420-TXK [cytosol] (R-HSA-3448734)	0.556	3
UniProt:O95994 AGR2			0.556	5
UniProt:A0JLT2-2 MED19			0.556	3
UniProt:Q92558 WASF1	3	p-Y151,S,T-WASF1 [cytosol] (R-HSA-5672390) WASF1 [cytosol] (R-HSA-200965) p-Y151-WASF1 [cytosol] (R-HSA-2029058)	0.556	3
UniProt:Q7L190 DPPA4	1	DPPA4 [nucleoplasm] (R-HSA-452999)	0.556	3
UniProt:Q6ZU52 K0408			0.556	3
UniProt:Q8N4B1-4 PHETA1			0.556	3
UniProt:Q03989 ARI5A			0.556	3
UniProt:P27986-2 PIK3R1			0.556	3
UniProt:Q6UY14-3 ADAMTSL4			0.556	3
UniProt:Q6ZNG0 ZNF620	1	ZNF620 [nucleoplasm] (R-HSA-2127603)	0.556	3
UniProt:Q9Y330 ZBT12			0.556	5
UniProt:Q6IQ23-2 PLEKHA7			0.556	3
UniProt:Q8N9I9 DTX3			0.556	3
UniProt:Q86SG2 ANR23			0.556	3
UniProt:Q9BRR9 ARHGAP9	3	ARHGAP9 [extracellular region] (R-HSA-6806529) ARHGAP9 [cytosol] (R-HSA-2976572) ARHGAP9 [secretory granule lumen] (R-HSA-6804973)	0.556	3
UniProt:Q9HB07 MYG1			0.556	3
UniProt:Q9BRT8 CBWD1			0.556	3
UniProt:Q9GZT8 NIF3L			0.556	3
UniProt:Q96D03 DDT4L			0.556	3
UniProt:A8MW99 MEI4			0.556	3
UniProt:B1AHC3 B1AHC3			0.556	3
UniProt:Q8N684-3 CPSF7			0.556	3
IntAct:EBI-22412087 CCSB ORF ID			0.556	3
UniProt:Q06418 TYRO3			0.556	3
IntAct:EBI-10220116 163154			0.556	3
IntAct:EBI-10178797 4005			0.556	3
UniProt:Q9UNY5 ZN232			0.556	3
UniProt:Q6S9Z5 ZN474			0.556	3
UniProt:P62324 BTG1	1	BTG1 [nucleoplasm] (R-HSA-9620886)	0.556	3
UniProt:Q96PV4 PNMA5			0.556	3
UniProt:O14512 SOCS7			0.556	3
UniProt:Q13625-3 TP53BP2			0.556	3
UniProt:Q13322-4 GRB10			0.556	3
UniProt:Q5JST6 EFHC2			0.556	3
UniProt:O15156 ZBT7B			0.556	3
UniProt:Q15907 RAB11B	3	GGC-RAB11B [cytosol] (R-HSA-8873766) RAB11B [recycling endosome membrane] (R-HSA-8854762) RAB11B [cytosol] (R-HSA-8873671)	0.556	3
UniProt:Q08117 TLE5	1	AES [nucleoplasm] (R-HSA-4648963)	0.556	3
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.556	3
UniProt:Q9UIH9 KLF15	1	KLF15 [nucleoplasm] (R-HSA-8878735)	0.556	3
UniProt:Q92841 DDX17	2	SUMO1-K50-DDX17 [nucleoplasm] (R-HSA-3900104) DDX17 [nucleoplasm] (R-HSA-3900090)	0.556	3
UniProt:P48634 PRC2A			0.553	2
UniProt:Q09472 EP300	5	Foxo4-S-S-EP300 [nucleoplasm] (R-HSA-9617720) SUMO1-K1020,1024-EP300 [nucleoplasm] (R-HSA-3899306) FOXO4-S-S-EP300 [nucleoplasm] (R-HSA-9617691) p-S,T-EP300 [nucleoplasm] (R-HSA-8878072) EP300 [nucleoplasm] (R-HSA-381325)	0.553	2
UniProt:Q8WUM4 PDCD6IP	1	PDCD6IP [cytosol] (R-HSA-917717)	0.553	2
UniProt:Q06187 BTK	6	p-Y223,Y551-BTK [cytosol] (R-HSA-2424454) Active BTK [cytosol] (R-HSA-8964323) p-Y551-BTK [cytosol] (R-HSA-2685603) p-Y551-BTK [plasma membrane] (R-HSA-9606165) p-Y223,Y551-BTK [plasma membrane] (R-HSA-984807) BTK [cytosol] (R-HSA-197948)	0.547	2
UniProt:Q5JSH3 WDR44			0.547	2
UniProt:Q01082 SPTBN1	3	SPTBN1(2-159)-p-6Y FLT3(570-993) fusion [cytosol] (R-HSA-9703317) SPTBN1(2-159)-FLT3(570-993) fusion [cytosol] (R-HSA-9703316) SPTBN1 [cytosol] (R-HSA-420048)	0.547	2
UniProt:P05787 KRT8	1	KRT8 [cytosol] (R-HSA-446043)	0.547	3
UniProt:Q92734 TFG	1	TFG [cytosol] (R-HSA-5688159)	0.547	2
UniProt:O75083 WDR1	2	WDR1 [cytosol] (R-HSA-350699) WDR1 [extracellular region] (R-HSA-350752)	0.547	2
UniProt:P19338 NCL	1	NCL [nucleoplasm] (R-HSA-6791213)	0.547	2
UniProt:O43295 SRGAP3	1	SRGAP3 [cytosol] (R-HSA-428463)	0.544	2
UniProt:Q9Y2R2 PTPN22	1	PTPN22 [cytosol] (R-HSA-8852205)	0.544	2
UniProt:Q9UQ16 DNM3	2	DNM3 [plasma membrane] (R-HSA-443610) DNM3 [cytosol] (R-HSA-2213188)	0.527	3
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.527	3
UniProt:P14618 PKM	3	PKM [extracellular region] (R-HSA-6806491) PKM [ficolin-1-rich granule lumen] (R-HSA-6801387) PKM [secretory granule lumen] (R-HSA-6801401)	0.527	2
UniProt:Q9UQ16-2 DNM3			0.527	2
UniProt:Q99816 TSG101	1	TSG101 [endosome membrane] (R-HSA-2980549)	0.527	3
UniProt:P05141 SLC25A5	1	SLC25A5 [mitochondrial inner membrane] (R-HSA-49743)	0.527	3
UniProt:Q9H7D0 DOCK5	1	DOCK5 [cytosol] (R-HSA-1012991)	0.527	3
UniProt:P27708 CAD	1	CAD [cytosol] (R-HSA-73452)	0.527	3
UniProt:Q9H9H4 VPS37B	1	VPS37B [endosome membrane] (R-HSA-184293)	0.527	3
UniProt:P42338 PIK3CB	1	PIK3CB [cytosol] (R-HSA-74788)	0.527	2
UniProt:Q9H792 PEAK1	1	PEAK1 [cytosol] (R-HSA-9715162)	0.527	2
UniProt:P12236 SLC25A6	2	SLC25A6 [mitochondrial inner membrane] (R-HSA-49745) SLC25A6 [mitochondrial intermembrane space] (R-HSA-1955374)	0.527	2
UniProt:O43426 SYNJ1	1	SYNJ1 [cytosol] (R-HSA-1604634)	0.527	2
UniProt:Q93079 H2BC9	9	Ub-HIST1H2BH [nucleoplasm] (R-HSA-6782558) HIST1H2BH [extracellular region] (R-HSA-977580) AcK-HIST1H2BH [nucleoplasm] (R-HSA-4549241) AcK16-HIST1H2BH [nucleoplasm] (R-HSA-4568682) AcK6-HIST1H2BH [nucleoplasm] (R-HSA-4568718) AcK21-HIST1H2BH [nucleoplasm] (R-HSA-4568657) AcK13-HIST1H2BH [nucleoplasm] (R-HSA-4568705) Ub-121-HIST1H2BH [nucleoplasm] (R-HSA-3364021) HIST1H2BH [nucleoplasm] (R-HSA-181915)	0.527	2
UniProt:Q75VX8 GARE2			0.527	2
UniProt:P22626 HNRNPA2B1	2	HNRNPA2B1 [extracellular exosome] (R-HSA-8950304) HNRNPA2B1 [nucleoplasm] (R-HSA-71929)	0.527	2
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.527	3
UniProt:Q8TF42 UBS3B			0.527	3
UniProt:Q00325 MPCP			0.527	2
UniProt:Q96RF0-2 SNX18			0.527	2
UniProt:Q13480-2 GAB1			0.527	2
UniProt:Q9H939 PPIP2			0.527	2
UniProt:P62805 H4C1	19	SUMO3-HIST1H4 [nucleoplasm] (R-HSA-4570531) HIST1H4A [extracellular region] (R-HSA-977569) SUMO1-HIST1H4 [nucleoplasm] (R-HSA-4570518) 4xAcK-HIST1H4A [nucleoplasm] (R-HSA-427390) AcK5,12-HIST1H4A [nucleoplasm] (R-HSA-212078) AcK17-HIST1H4 [nucleoplasm] (R-HSA-427469) AcK13-HIST1H4 [nucleoplasm] (R-HSA-4568744) AcK6-HIST1H4 [nucleoplasm] (R-HSA-4568748) AcK17-HIST1H4 [nucleoplasm] (R-HSA-4568749) AcK9-HIST1H4 [nucleoplasm] (R-HSA-4568758) Me2aR4-HIST1H4 [nucleoplasm] (R-HSA-5229015) Me2sR4-HIST1H4 [nucleoplasm] (R-HSA-4754243) MeR4-HIST1H4 [nucleoplasm] (R-HSA-4754240) Me3K21-HIST1H4 [nucleoplasm] (R-HSA-5651656) MeK21-HIST1H4 [nucleoplasm] (R-HSA-5423110) AcK-HIST1H4 [nucleoplasm] (R-HSA-3451124) MeK-HIST1H4A [nucleoplasm] (R-HSA-2172676) HIST1H4 [nucleoplasm] (R-HSA-181902) Me2K21-HIST1H4 [nucleoplasm] (R-HSA-5651652)	0.527	2
UniProt:P04792 HSPB1	3	p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) HSPB1 [cytosol] (R-HSA-450563) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.527	3
UniProt:P07355 ANXA2	4	ANXA2 [external side of plasma membrane] (R-HSA-5336164) ANXA2 [cytosol] (R-HSA-5263667) ANXA2 [extracellular region] (R-HSA-6806242) ANXA2 [azurophil granule lumen] (R-HSA-6798766)	0.527	2
UniProt:P62937 PPIA	5	PPIA [ficolin-1-rich granule lumen] (R-HSA-6801391) PPIA [extracellular exosome] (R-HSA-6801538) PPIA [secretory granule lumen] (R-HSA-6801400) PPIA [extracellular region] (R-HSA-173646) PPIA [cytosol] (R-HSA-173123)	0.527	2
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.527	3
UniProt:Q9Y230 RUVBL2	1	RUVBL2 [nucleoplasm] (R-HSA-418321)	0.527	2
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.527	3
UniProt:P19105 MYL12A	2	MYL12A [cytosol] (R-HSA-390735) p-S19-MYL12A [cytosol] (R-HSA-390749)	0.527	2
UniProt:Q9Y265 RUVBL1	1	RUVBL1 [nucleoplasm] (R-HSA-418323)	0.527	2
UniProt:P11142 HSPA8	10	HSPA8 [nucleoplasm] (R-HSA-5082380) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [cytosol] (R-HSA-264476)	0.527	3
UniProt:P13639 EEF2	10	EEF2 [extracellular region] (R-HSA-6806499) EEF2 [secretory granule lumen] (R-HSA-6801504) EEF2 [ficolin-1-rich granule lumen] (R-HSA-6801513) aminocarboxypropyl EEF2 [cytosol] (R-HSA-5358478) Me-diphthine EEF2 [cytosol] (R-HSA-5367025) nascent EEF2 [cytosol] (R-HSA-5358472) diphthine EEF2 [cytosol] (R-HSA-5358501)