RUNX2 binds RB1

Stable Identifier
R-HSA-8985460
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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RUNX2 forms a complex with the tumor suppressor RB1. The C-terminus and B-pocket of RB1 are needed for the interaction (Thomas et al. 2001).

Literature References
PubMed ID Title Journal Year
11545733 The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation

Thomas, DM, Carty, SA, Piscopo, DM, Lee, JS, Wang, WF, Forrester, WC, Hinds, PW

Mol. Cell 2001
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