RUNX2 binds RB1

Stable Identifier
R-HSA-8985460
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RUNX2 binds RB1
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RUNX2 forms a complex with the tumor suppressor RB1. The C-terminus and B-pocket of RB1 are needed for the interaction (Thomas et al. 2001).
Literature References
PubMed ID Title Journal Year
11545733 The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation

Thomas, DM, Wang, WF, Carty, SA, Forrester, WC, Lee, JS, Hinds, PW, Piscopo, DM

Mol. Cell 2001
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Runx2 binds RB1 (Homo sapiens)
Authored
Orlic-Milacic, M  (2017-04-17)
Reviewed
Ducy, P  (2017-08-04)
Created
Orlic-Milacic, M  (2017-04-17)
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