JAK1 binds IFNLR1

Stable Identifier
R-HSA-8987120
Type
Reaction [binding]
Species
Homo sapiens
Compartment
Synonyms
JAK1 binds IL28RA
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Tyrosine protein kinase JAK1 (JAK1) binds Interferon lambda receptor 1 (IFNLR1).
The Box1 of IFNLR1 binds to the F2 subdomain of the JAK1 FERM, in a cleft formed by helices F2 alpha2, F2 alpha3, and F2 alpha4 (Ferrao et al. 2017).

Literature References
PubMed ID Title Journal Year
28458652 The Janus Kinase (JAK) FERM and SH2 Domains: Bringing Specificity to JAK-Receptor Interactions

Ferrao, R, Lupardus, PJ

Front Endocrinol (Lausanne) 2017
Participants
Participant Of
Orthologous Events
Authored
Reviewed
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